LOCUS       NM_001003750             933 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 8 subfamily I member 2
            (OR8I2), mRNA.
ACCESSION   NM_001003750
VERSION     NM_001003750.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 933)
  AUTHORS   Demirkan,A., van Duijn,C.M., Ugocsai,P., Isaacs,A.,
            Pramstaller,P.P., Liebisch,G., Wilson,J.F., Johansson,A., Rudan,I.,
            Aulchenko,Y.S., Kirichenko,A.V., Janssens,A.C., Jansen,R.C.,
            Gnewuch,C., Domingues,F.S., Pattaro,C., Wild,S.H., Jonasson,I.,
            Polasek,O., Zorkoltseva,I.V., Hofman,A., Karssen,L.C.,
            Struchalin,M., Floyd,J., Igl,W., Biloglav,Z., Broer,L., Pfeufer,A.,
            Pichler,I., Campbell,S., Zaboli,G., Kolcic,I., Rivadeneira,F.,
            Huffman,J., Hastie,N.D., Uitterlinden,A., Franke,L., Franklin,C.S.,
            Vitart,V., Nelson,C.P., Preuss,M., Bis,J.C., O'Donnell,C.J.,
            Franceschini,N., Witteman,J.C., Axenovich,T., Oostra,B.A.,
            Meitinger,T., Hicks,A.A., Hayward,C., Wright,A.F., Gyllensten,U.,
            Campbell,H. and Schmitz,G.
  CONSRTM   DIAGRAM Consortium; CARDIoGRAM Consortium; CHARGE Consortium;
            EUROSPAN consortium
  TITLE     Genome-wide association study identifies novel loci associated with
            circulating phospho- and sphingolipid concentrations
  JOURNAL   PLoS Genet 8 (2), e1002490 (2012)
   PUBMED   22359512
REFERENCE   2  (bases 1 to 933)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   3  (bases 1 to 933)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB065656.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC137007.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000302124.8/ ENSP00000303864.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..933
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..933
                     /gene="OR8I2"
                     /gene_synonym="OR11-170"
                     /note="olfactory receptor family 8 subfamily I member 2"
                     /db_xref="GeneID:120586"
                     /db_xref="HGNC:HGNC:15310"
     CDS             1..933
                     /gene="OR8I2"
                     /gene_synonym="OR11-170"
                     /note="olfactory receptor OR11-170"
                     /codon_start=1
                     /product="olfactory receptor 8I2"
                     /protein_id="NP_001003750.1"
                     /db_xref="CCDS:CCDS31517.1"
                     /db_xref="GeneID:120586"
                     /db_xref="HGNC:HGNC:15310"
                     /translation="MAGNNFTEVTVFILSGFANHPELQVSLFLMFLFIYLFTVLGNLG
                     LITLIRMDSQLHTPMYFFLSNLAFIDIFYSSTVTPKALVNFQSNRRSISFVGCFVQMY
                     FFVGLVCCECFLLGSMAYNRYIAICNPLLYSVVMSQKVSNWLGVMPYVIGFTSSLISV
                     WVISSLAFCDSSINHFFCDTTALLALSCVDTFGTEMVSFVLAGFTLLSSLLIITVTYI
                     IIISAILRIQSAAGRQKAFSTCASHLMAVTIFYGSLIFTYLQPDNTSSLTQAQVASVF
                     YTIVIPMLNPLIYSLRNKDVKNALLRVIHRKLFP"
     exon            1..933
                     /gene="OR8I2"
                     /gene_synonym="OR11-170"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggctggca acaatttcac tgaggttacc gtcttcatcc tctctggatt tgcaaatcac
       61 cctgaattac aagtcagtct tttcttgatg tttctcttca tttatctatt cactgttttg
      121 ggaaacctgg gactgatcac gttaatcaga atggattctc agcttcacac ccctatgtac
      181 tttttcctga gcaatttagc atttattgac atattttact cctctactgt aacacctaag
      241 gcattggtga atttccaatc caatcggaga tccatctcct ttgttggctg ctttgttcaa
      301 atgtactttt ttgttggatt ggtgtgttgt gagtgtttcc ttctgggatc aatggcctac
      361 aatcgctaca tagcaatctg caatccctta ctgtattcag tagtcatgtc ccaaaaagtg
      421 tccaactggc tgggagtaat gccatatgtg ataggcttca caagctcgct gatatctgtc
      481 tgggtgataa gcagtttggc gttctgtgat tccagcatca atcatttttt ttgtgacacc
      541 acagctcttt tagcactctc ctgtgtagat acattcggca cagaaatggt gagctttgtc
      601 ttagctggat tcactcttct tagctctctc cttatcatca cagtcactta tatcatcatc
      661 atctcagcca tcctgaggat ccagtcagca gcaggcaggc agaaggcctt ctccacctgc
      721 gcatcccacc tcatggctgt aactatcttt tatgggtctc tgattttcac ctatttgcaa
      781 cctgataaca catcatcgct gacccaggcg caggtggcat ctgtattcta tacgattgtc
      841 attcccatgc tgaatccact catctacagt ctgaggaaca aagatgtgaa aaatgctctt
      901 ctgagagtca tacatagaaa actttttcca tga
//
