LOCUS       NM_001005199            2927 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 8 subfamily H member 1
            (OR8H1), mRNA.
ACCESSION   NM_001005199 XM_166823
VERSION     NM_001005199.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2927)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC022882.5.
            
            On Aug 5, 2020 this sequence version replaced NM_001005199.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641600.1/ ENSP00000493316.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-304               AC022882.5         102700-103003       c
            305-2927            AC022882.5         99211-101833        c
FEATURES             Location/Qualifiers
     source          1..2927
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..2927
                     /gene="OR8H1"
                     /gene_synonym="OR11-180"
                     /note="olfactory receptor family 8 subfamily H member 1"
                     /db_xref="GeneID:219469"
                     /db_xref="HGNC:HGNC:14824"
     exon            1..304
                     /gene="OR8H1"
                     /gene_synonym="OR11-180"
                     /inference="alignment:Splign:2.1.0"
     exon            305..2927
                     /gene="OR8H1"
                     /gene_synonym="OR11-180"
                     /inference="alignment:Splign:2.1.0"
     CDS             327..1262
                     /gene="OR8H1"
                     /gene_synonym="OR11-180"
                     /note="olfactory receptor OR11-180"
                     /codon_start=1
                     /product="olfactory receptor 8H1"
                     /protein_id="NP_001005199.1"
                     /db_xref="CCDS:CCDS31526.1"
                     /db_xref="GeneID:219469"
                     /db_xref="HGNC:HGNC:14824"
                     /translation="MGRRNNTNVPDFILTGLSDSEEVQMALFILFLLIYLITMLGNVG
                     MILIIRLDLQLHTPMYFFLTHLSFIDLSYSTVITPKTLANLLTSNYISFMGCFAQMFF
                     FVFLGAAECFLLSSMAYDRYVAICSPLRYPVIMSKRLCCALVTGPYVISFINSFVNVV
                     WMSRLHFCDSNVVRHFFCDTSPILALSCMDTYDIEIMIHILAGSTLMVSLITISASYV
                     SILSTILKINSTSGKQKALSTCASHLLGVTIFYGTMIFTYLKPRKSYSLGRDQVASVF
                     YTIVIPMLNPLIYSLRNKEVKNALIRVMQRRQDSR"
     regulatory      2529..2534
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR8H1"
                     /gene_synonym="OR11-180"
                     /note="hexamer: AATAAA"
     polyA_site      2545
                     /gene="OR8H1"
                     /gene_synonym="OR11-180"
                     /note="major polyA site"
ORIGIN      
        1 aataatctac ctatagtcac agagattccc agtgttcttt tgacacacaa cttcctggta
       61 atctttccat ttgaccagga cctaaacgaa atttctaggt tggttttttg acacagaata
      121 aaacaaaatg aatgcacaaa aatgtaaaaa caacttatct caaggaaaac aaatattata
      181 tcggagaaaa ttttatctcc ttaaatggtt ttcatatttt atttataaga aaaattgagg
      241 ttgacaaatt tctagacaga taatatgaga agaaagcttt ttcaccaact ttggctcaga
      301 cacgcagttt aaagcaattg aacatcatgg gtagaagaaa taacacaaat gtgcctgact
      361 tcatccttac gggactgtca gattctgaag aggtccagat ggccctcttt atactatttc
      421 tcctgatata cctaattact atgctgggca atgtggggat gatattgata atccgcctgg
      481 acctccagct tcacactccc atgtattttt tccttactca cttgtcattt attgacctca
      541 gttactcaac tgtcatcaca cctaaaacct tagcgaactt actgacttcc aactatattt
      601 ccttcatggg ctgctttgcc cagatgttct tttttgtctt cttgggagct gctgaatgtt
      661 ttcttctctc atcaatggcc tatgatcgct acgtagctat ctgcagtcct ctacgttacc
      721 cagttattat gtccaaaagg ctgtgttgcg ctcttgtcac tgggccctat gtgattagct
      781 ttatcaactc ctttgtcaat gtggtttgga tgagcagact gcatttctgc gactcaaatg
      841 tagttcgtca ctttttctgc gacacgtctc caattttagc tctgtcctgc atggacacat
      901 acgacattga aatcatgata cacattttag ctggttccac cctgatggtg tcccttatca
      961 caatatctgc atcctatgtg tccattctct ctaccatcct gaaaattaat tccacttcag
     1021 gaaagcagaa agctttgtct acttgtgcct ctcatctctt gggagtcacc atcttttatg
     1081 gaactatgat ttttacttat ttaaaaccaa gaaagtctta ttctttggga agggatcaag
     1141 tggcttctgt tttttatact attgtgattc ccatgctgaa tccactcatt tatagtctta
     1201 gaaacaaaga agttaaaaat gctctcatta gagtcatgca gagaagacag gactccaggt
     1261 aattaaaata gcaggaatgc tgaacattta aactcatctt ttctttcttt tctatttggt
     1321 atgtccttgg tctccctata aaaacaattg aatccttcat gtttgcattt ctgttgtgct
     1381 aacctttgct tgactaaacg tgatcttgaa catttcaagg tgtatgtttt cagaaatcca
     1441 gattgtaatt agaaatcata atatgtgttg gccgggcacg gtggctcatg cctataatcc
     1501 cagcactctg ggaggccgag gtgggtggat cacatgaggt cagaagttca agaccagcct
     1561 agccatgatg aaatgtggtc tgtagtaaaa atacaaaaaa ttagctgggt gtggtggtgc
     1621 atgcctgtaa tcccagctac ttgcggggct gaggtaggag aatcgcttca atctgggagg
     1681 cagaggttgc agtgagccga gatcgtgcca ttggactcca gcctgggcaa caagagcgaa
     1741 actccgtctc aaaacaaaac agaacaaaac aaaacaaaac aaaaaataat aatatgtgtg
     1801 tcatatttac agtctaaata tatgttttta gaagcaactg atgtggaaaa taagaaaata
     1861 tggttgtcct ttaaaattat attacacaaa ttcctatgca tacttcagtt gtaggtaaat
     1921 ttattatgga aaacaacgat ttggggcaca gtgataacag tctcagaagt tatttcattt
     1981 attatatggg gaagaattat aacagagtct ttaggagtac tgttttgaaa taaagttttc
     2041 caagagttag attctaaata tgctacattt tcagctatac aacccagaat atgttaccta
     2101 aaatttaaaa ctctctttcc ttaagtgcac aagataaata ataactccaa atttgatcag
     2161 agagtagctg taaagtattt aaggtgacaa taatcaatgc tgcctattct cattagaaga
     2221 cttgcattcc agcacaatgc cttttgtgaa ggatattcac ttgtgtttta caaattactt
     2281 ttggttaatt taatttacag gcacacaagc aactaaaaag gaaaaaaaaa gataatatca
     2341 gtagttcaca atttggactt taggaaataa aatattttga taaaattaag ttataataaa
     2401 atagcatata ttgttagaga aaatttgaaa aatattataa aatattaagg aaaatagaaa
     2461 ccctcaaaat attgagtttt ggctgttttg cttatggcat agccattctt ttgtttcttt
     2521 atttttctaa taaacttgtt ttcagtttaa gaaaaacaaa tatcgagttt tgtgcatgtt
     2581 cttcgagatc aatagttttg aatatgtgca tgtgtataac atatgtaaac taaatatcac
     2641 tttctgtgta ctgattttca gctttctgta tccatttaca agtttaacat tggataatct
     2701 ctttgtcatt gacaacgcta atataaattt tttcttggta cataggcaaa atcaagactc
     2761 atttcacaat gttttggact tgaaatatta actcaccaca ttaaaaatct acatgcagtg
     2821 atatctcttt tgtgtgttaa acatttgaaa acttgacttc tgtaaagagt caaactgttt
     2881 ctttgttaaa attctgtgtg tttttaaaaa tcattgcctt gctcctg
//
