LOCUS       NM_001005198            1566 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 8 subfamily G member 5
            (OR8G5), mRNA.
ACCESSION   NM_001005198 XM_166767
VERSION     NM_001005198.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1566)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP002965.3.
            
            On Jul 24, 2020 this sequence version replaced NM_001005198.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.240419.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2142348
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641992.2/ ENSP00000493127.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-259               AP002965.3         40346-40604
            260-1566            AP002965.3         48888-50194
FEATURES             Location/Qualifiers
     source          1..1566
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q24.2"
     gene            1..1566
                     /gene="OR8G5"
                     /gene_synonym="OR11-298; OR8G5P; OR8G6"
                     /note="olfactory receptor family 8 subfamily G member 5"
                     /db_xref="GeneID:219865"
                     /db_xref="HGNC:HGNC:19622"
     exon            1..259
                     /gene="OR8G5"
                     /gene_synonym="OR11-298; OR8G5P; OR8G6"
                     /inference="alignment:Splign:2.1.0"
     exon            260..1566
                     /gene="OR8G5"
                     /gene_synonym="OR11-298; OR8G5P; OR8G6"
                     /inference="alignment:Splign:2.1.0"
     CDS             274..1209
                     /gene="OR8G5"
                     /gene_synonym="OR11-298; OR8G5P; OR8G6"
                     /note="olfactory receptor, family 8, subfamily G, member
                     6; olfactory receptor, family 8, subfamily G, member 5
                     pseudogene; olfactory receptor OR11-298; olfactory
                     receptor 8G6"
                     /codon_start=1
                     /product="olfactory receptor 8G5"
                     /protein_id="NP_001005198.2"
                     /db_xref="CCDS:CCDS66256.2"
                     /db_xref="GeneID:219865"
                     /db_xref="HGNC:HGNC:19622"
                     /translation="MAAENHSFVTKFILVGLTEKSELQLPLFLVFLGIYVVTVLGNLG
                     MITLIGLSSHLHTPMYCFLSSLSFIDFCHSTVITPKMLVNFVTEKNIISYPECMTQLY
                     FFLVFAIAECHMLAAMAYDGYVAICSPLLYSIIISNKACFSLILVVYVIGLICASAHI
                     GCMFRVQFCKFDVINHYFCDLISILKLSCSSTYINELLILIFSGINILVPSLTILSSY
                     IFIIASILRIRYTEGRSKAFSTCSSHISAVSVFFGSAAFMYLQPSSVSSMDQGKVSSV
                     FYTIVVPMLNPLIYSLRNKDVHVALKKTLGKRTFL"
     regulatory      1532..1537
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR8G5"
                     /gene_synonym="OR11-298; OR8G5P; OR8G6"
                     /note="hexamer: AATAAA"
     polyA_site      1566
                     /gene="OR8G5"
                     /gene_synonym="OR11-298; OR8G5P; OR8G6"
                     /note="major polyA site"
ORIGIN      
        1 aggccactgt aaaaggggag gatgtgtgct agagctagag aaacacaact gaaaagtgac
       61 aactggagat gctgatcagc ggtgcagatt gatttcaaaa gtgagtgaga tgtcttgtgc
      121 tttgcagtct caggactaaa gactacagaa cgctggcttg gtacctatga cttccaacag
      181 cagcattagt gccattctcc aagtcaaaga cagcaagttg caaataaaat ttggaactga
      241 ggtttcaggc aaaagaaaga aactcatcaa agaatggcag cagaaaacca ttcttttgtg
      301 actaagttta ttctggttgg gctaacagag aagtcagagc tacagctgcc cctcttcctc
      361 gtcttcctgg gaatctatgt agtcacagtg ctggggaacc tgggcatgat cacactgatt
      421 gggctcagtt ctcacctgca cacacctatg tactgtttcc tcagcagtct gtccttcatt
      481 gacttctgcc attccactgt cattacccct aagatgctgg tgaactttgt gacagagaag
      541 aacatcatct cctaccctga atgcatgact cagctctact tcttcctcgt ttttgctatt
      601 gcagagtgtc acatgttggc tgcaatggca tatgacggct acgtggccat ctgtagcccc
      661 ttgctgtaca gcatcatcat atccaataag gcttgctttt ctctgatttt agtggtgtat
      721 gtaataggcc tgatttgtgc gtcagctcat ataggctgta tgtttagggt tcaattctgc
      781 aaatttgatg tgatcaacca ttatttctgt gatcttattt ctatcttgaa gctctcctgt
      841 tctagtactt acattaatga gttactgatt ttaatcttta gtggaattaa catccttgtc
      901 cccagcctga ccatcctcag ctcttacatc ttcatcattg ccagcatcct ccgcattcgc
      961 tacactgagg gcaggtccaa agccttcagc acttgcagct cccacatctc ggctgtttct
     1021 gttttctttg ggtctgcagc attcatgtac ctgcagccat catctgtcag ctccatggac
     1081 caggggaaag tgtcctctgt gttttatact attgttgtgc ccatgctgaa ccccctgatc
     1141 tacagcctga ggaataaaga tgtccacgtt gccctgaaga aaacgctagg gaaaagaaca
     1201 ttcttatgaa cagaagtaca atgaaaaaga ttgcattaga tctaagtttt tggctatgat
     1261 attgtatgaa atgatgtctt tcactttagt gcatctgtca acattctttc taatttgggg
     1321 ggattttact gacgttatgt cttatgcaca tggtctattt catgccattt ccctctcatt
     1381 ttttctctca taaggattac gaagacatga tattttctta gaagaaataa taagattgac
     1441 atagtgaaat agtggcataa cctgataatg ccagttacat tcccttcccc cttttctttc
     1501 atgtaattga ttaaaacata ctcctcaaca taataaaaac actatcttct ggtgataaaa
     1561 tactat
//
