LOCUS       NM_001002918             936 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 8 subfamily D member 2
            (OR8D2), mRNA.
ACCESSION   NM_001002918 XM_208541
VERSION     NM_001002918.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 936)
  AUTHORS   Olender,T., Waszak,S.M., Viavant,M., Khen,M., Ben-Asher,E.,
            Reyes,A., Nativ,N., Wysocki,C.J., Ge,D. and Lancet,D.
  TITLE     Personal receptor repertoires: olfaction as a model
  JOURNAL   BMC Genomics 13, 414 (2012)
   PUBMED   22908908
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 936)
  AUTHORS   Menashe,I., Aloni,R. and Lancet,D.
  TITLE     A probabilistic classifier for olfactory receptor pseudogenes
  JOURNAL   BMC Bioinformatics 7, 393 (2006)
   PUBMED   16939646
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 936)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   4  (bases 1 to 936)
  AUTHORS   Gaudin,J.C., Breuils,L. and Haertle,T.
  TITLE     New GPCRs from a human lingual cDNA library
  JOURNAL   Chem Senses 26 (9), 1157-1166 (2001)
   PUBMED   11705801
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF162668.1.
            
            On Aug 30, 2004 this sequence version replaced XM_208541.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jun 2015].
            
            Sequence Note: This gene is a segregating pseudogene. This RefSeq
            represents the protein encoded by the reference genome allele,
            which is predicted to be non-functional as an olfactory receptor
            according to the Classifier for Olfactory Receptor Pseudogenes.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AF162668.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000624618.2/ ENSP00000485661.1
            polymorphic pseudogene :: PMID: 22908908
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..936
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q24.2"
     gene            1..936
                     /gene="OR8D2"
                     /gene_synonym="JCG2"
                     /note="olfactory receptor family 8 subfamily D member 2"
                     /db_xref="GeneID:283160"
                     /db_xref="HGNC:HGNC:8482"
     CDS             1..936
                     /gene="OR8D2"
                     /gene_synonym="JCG2"
                     /note="olfactory receptor-like protein JCG2; olfactory
                     receptor OR11-303"
                     /codon_start=1
                     /product="olfactory receptor 8D2"
                     /protein_id="NP_001002918.1"
                     /db_xref="GeneID:283160"
                     /db_xref="HGNC:HGNC:8482"
                     /translation="MATSNHSSGAEFILAGLTQRPELQLPLFLLFLGIYVVTVVGNLG
                     MIFLIALSSQLYPPVYYFLSHLSFIDLCYSSVITPKMLVNFVPEENIISFLECITQLY
                     FFLIFVIAEGYLLTAMEYDRYVAICRPLLYNIVMSHRVCSIMMAVVYSLGFLWATVHT
                     TRMSVLSFCRSHTVSHYFCDILPLLTLSCSSTHINEILLFIIGGVNTLATTLAVLISY
                     AFIFSSILGIHSTEGQSKAFGTCSSHLLAVGIFFGSITFMYFKPPSSTTMEKEKVSSV
                     FYITIIPMLNPLIYSLRNKDVKNALKKMTRGRQSS"
     exon            1..936
                     /gene="OR8D2"
                     /gene_synonym="JCG2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggctactt caaaccattc ttcaggggct gagtttatcc tggcaggctt gacacaacgc
       61 ccagaacttc aactgccact cttcctcctg ttccttggaa tatatgtggt cacagtggtg
      121 gggaacctgg gcatgatctt cttaattgct ctcagttctc aactttaccc tccagtgtat
      181 tattttctca gtcatttgtc tttcattgat ctctgctact cctctgtcat tacccctaag
      241 atgctggtga actttgttcc agaggagaac attatctcct ttctggaatg cattactcaa
      301 ctttatttct tccttatttt tgtaattgca gaaggctacc ttctgacagc catggaatat
      361 gaccgttatg ttgctatctg tcgcccactg ctttacaata ttgtcatgtc ccacagggtc
      421 tgttccataa tgatggctgt ggtatactca ctgggttttc tgtgggccac agtccatact
      481 acccgcatgt cagtgttgtc attctgtagg tctcatacgg tcagtcatta tttttgtgat
      541 attctcccct tattgactct gtcttgctcc agcacccaca tcaatgagat tctgctgttc
      601 attattggag gagttaatac cttagcaact acactggcgg tccttatctc ttatgctttc
      661 attttctcta gtatccttgg tattcattcc actgaggggc aatccaaagc ctttggcact
      721 tgtagctccc atctcttggc tgtgggcatc ttttttgggt ctataacatt catgtatttc
      781 aagccccctt ccagcactac tatggaaaaa gagaaggtgt cttctgtgtt ctacatcaca
      841 ataatcccca tgctgaatcc tctaatctat agcctgagga acaaggatgt gaaaaatgca
      901 ctgaagaaga tgactagggg aaggcagtca tcctga
//
