LOCUS       NM_001005467            2170 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 8 subfamily B member 3
            (OR8B3), mRNA.
ACCESSION   NM_001005467 XM_372441
VERSION     NM_001005467.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2170)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP001804.5.
            
            On Jul 22, 2020 this sequence version replaced NM_001005467.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641139.1/ ENSP00000493120.1
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-335               AP001804.5         95443-95777         c
            336-2170            AP001804.5         92287-94121         c
FEATURES             Location/Qualifiers
     source          1..2170
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q24.2"
     gene            1..2170
                     /gene="OR8B3"
                     /gene_synonym="OR11-311"
                     /note="olfactory receptor family 8 subfamily B member 3"
                     /db_xref="GeneID:390271"
                     /db_xref="HGNC:HGNC:8472"
     exon            1..335
                     /gene="OR8B3"
                     /gene_synonym="OR11-311"
                     /inference="alignment:Splign:2.1.0"
     exon            336..2170
                     /gene="OR8B3"
                     /gene_synonym="OR11-311"
                     /inference="alignment:Splign:2.1.0"
     CDS             353..1294
                     /gene="OR8B3"
                     /gene_synonym="OR11-311"
                     /note="olfactory receptor OR11-311"
                     /codon_start=1
                     /product="olfactory receptor 8B3"
                     /protein_id="NP_001005467.1"
                     /db_xref="CCDS:CCDS31709.1"
                     /db_xref="GeneID:390271"
                     /db_xref="HGNC:HGNC:8472"
                     /translation="MLARNNSLVTEFILAGLTDHPEFQQPLFFLFLVVYIVTMVGNLG
                     LIILFGLNSHLHTPMYYFLFNLSFIDLCYSSVFTPKMLMNFVSKKNIISYVGCMTQLF
                     FFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSHQVCSMLTFAAYIMGLAGATAHT
                     GCMLRLTFCSANIINHYLCDILPLLQLSCTSTYVNEVVVLIVVGINIMVPSCTILISY
                     VFIVTSILHIKSTQGRSKAFSTCSSHVIALSLFFGSAAFMYIKYSSGSMEQGKVSSVF
                     YTNVVPMLNPLIYSLRNKDVKVALRKALIKIQRRNIF"
ORIGIN      
        1 acttactggg ggatatgtaa tcaggtccaa aagaattgta agccttgagc aaatgccatg
       61 tgctctatga catggtagct ctggtttgaa gtgcagtttt ccaacaaacc ctcttggcaa
      121 atttataaat aatagtttga tctacaccac aaaatgattc ccagaacatt cagattctga
      181 gatctctgct caatgctttt gccagtcaag ggagaagaag attctgtgac tacatctgat
      241 caacatagat accttcacag ccatttcttc ctccagggca gtggaggtga aacacatatc
      301 aatggtcagc actgagttct ctgagtggaa ggaagatttt tgaagacaaa aaatgctggc
      361 tagaaacaac tccttagtga ctgaatttat tcttgctgga ttaacagatc atccagagtt
      421 ccagcaaccc ctctttttcc tgtttctagt ggtctacatt gtcaccatgg taggcaacct
      481 tggcttgatc attcttttcg gtctaaattc tcacctccac acaccaatgt actatttcct
      541 cttcaatctc tccttcattg atctctgtta ctcctctgtt ttcactccca aaatgctaat
      601 gaactttgta tcaaaaaaga atattatctc ctatgttggg tgcatgactc agctgttttt
      661 ctttctcttt tttgtcatct ctgaatgtta catgttgacc tcaatggcat atgatcgcta
      721 tgtggccatc tgtaatccat tgctgtataa ggtcaccatg tcccatcagg tctgttctat
      781 gctcactttt gctgcttaca taatgggatt ggctggagcc acggcccaca ccgggtgcat
      841 gcttagactc accttctgca gtgctaatat catcaaccat tacttgtgtg acatactccc
      901 cctcctccag ctttcctgca ccagcaccta tgtcaacgag gtggttgttc tcattgttgt
      961 gggtattaat atcatggtac ccagttgtac catcctcatt tcttatgttt tcattgtcac
     1021 tagcattctt catatcaaat ccactcaagg aagatcaaaa gccttcagta cttgtagctc
     1081 tcatgtcatt gctctgtctc tgttttttgg gtcagcggca ttcatgtata ttaaatattc
     1141 ttctggatct atggagcagg gaaaagtttc ttctgttttc tacactaatg tggtgcccat
     1201 gctcaatcct ctcatctaca gtttgaggaa caaggatgtc aaagttgcac tgaggaaagc
     1261 tctgattaaa attcagagaa gaaatatatt ctaattagaa gcagtaataa tgtaaaacga
     1321 ttgaagaact ttaaattttt attagtgtgt tccatgaaga gattttgttg tttctacaga
     1381 tggtgttatg tgtgatttaa taaacttgtc ttatcatttc tcttatgaaa tcatcttgtc
     1441 tctttttttg gttttgcatc tctggcactt ctcacaattt tactaaatag gtcatggcat
     1501 ctttgtaaaa ggaacatatg cactgatatt tttcattatc attttatatc cttcctctct
     1561 cctgggctgt tcttaattgg acatatatgg taaatttcat gaattataaa gatgtcaaag
     1621 tcacggcttt ctcacctaaa ctcagaagtg ccaaatatga tagaagcatt cttattttta
     1681 tcaacattgt tacagatata ggcagctgga tttgatgaaa tgtctccatt acaaatggta
     1741 ggtagcttaa agcagaatga gcaccccttg atcttgtcct tttgttctat attgtcacca
     1801 ttttgccttt tattattctg acttttcttg ttccctttga gaatggcaaa atttgtacca
     1861 catgccgttt gcttctgaga acctctatca gtccagtgca tttgatacag cagagaatat
     1921 gtgtgtctcc accttttatt gccaaaggca gcatttacag aggatgatta gagaaataat
     1981 acatgtggac ctcaggattc caataagtgg gtccattgtt tacattataa aactttcatt
     2041 cattgctatc taaaacagca ttgaaaattt tgaaaaaagc gtgtagttcc tactgtaaat
     2101 gttatttttt tactcgttat aggtaaatac tgcacattaa gttagcagaa atattttaca
     2161 caatggttac
//
