LOCUS       NM_001005468            1093 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 8 subfamily B member 2
            (OR8B2), mRNA.
ACCESSION   NM_001005468
VERSION     NM_001005468.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1093)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 1093)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP001804.5.
            
            On Aug 6, 2020 this sequence version replaced NM_001005468.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC018065.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641451.2/ ENSP00000493235.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-126               AP001804.5         81127-81252         c
            127-1093            AP001804.5         79147-80113         c
FEATURES             Location/Qualifiers
     source          1..1093
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q24.2"
     gene            1..1093
                     /gene="OR8B2"
                     /gene_synonym="OR11-309; OR11-310"
                     /note="olfactory receptor family 8 subfamily B member 2"
                     /db_xref="GeneID:26595"
                     /db_xref="HGNC:HGNC:8471"
     exon            1..126
                     /gene="OR8B2"
                     /gene_synonym="OR11-309; OR11-310"
                     /inference="alignment:Splign:2.1.0"
     exon            127..1093
                     /gene="OR8B2"
                     /gene_synonym="OR11-309; OR11-310"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..1085
                     /gene="OR8B2"
                     /gene_synonym="OR11-309; OR11-310"
                     /note="olfactory receptor OR11-309; olfactory receptor
                     OR11-310"
                     /codon_start=1
                     /product="olfactory receptor 8B2"
                     /protein_id="NP_001005468.1"
                     /db_xref="CCDS:CCDS31708.1"
                     /db_xref="GeneID:26595"
                     /db_xref="HGNC:HGNC:8471"
                     /translation="MLARNNSLVTEFILAGLTDHPEFRQPLFFLFLVIYIVTMVGNLG
                     LITLFGLNSHLHTPMYYFLFNLSFIDLCYSSVFTPKMLMNFVSKKNIISNVGCMTRLF
                     FFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSHQVCSMLTFAAYIMGLAGATAHT
                     GCMLRLTFCSANIINHYLCDILPLLQLSCTSTYVNEVVVLIVVGTNITVPSCTILISY
                     VFIVTSILHIKSTQGRSKAFSTCSSHVIALSLFFGSAAFMYIKYSSGSMEQGKVSSVF
                     YTNVVPMLNPLIYSLRNKDVKVALRKALIKIQRRNIF"
ORIGIN      
        1 gggagaagaa gattctttga ctacatgtgg tcaacgtaga taccttcacc accagttcta
       61 cctccagggc agtggaggtg aaacacatat caatggtcag cactgagttc tctgagtgga
      121 aggaagattt ttgaagacaa aaaatgctgg ctagaaacaa ctccttagtg actgaattta
      181 ttcttgctgg attaacagat catccagagt tccggcaacc cctctttttc ctgtttctag
      241 tgatctacat tgtcaccatg gtaggcaacc ttggcttgat cactcttttc ggtctaaatt
      301 ctcacctcca cacaccaatg tactatttcc tcttcaatct ctccttcatt gatctctgtt
      361 actcctctgt tttcactccc aaaatgctaa tgaactttgt gtcaaaaaag aatattatct
      421 ccaatgttgg gtgcatgact cggctgtttt tctttctctt tttcgtcatc tctgaatgtt
      481 acatgttgac ttcaatggca tatgatcgct atgtggccat ctgtaatcca ttgctgtata
      541 aggtcaccat gtcccatcag gtctgttcta tgctcacttt tgctgcttac ataatgggat
      601 tggctggagc cacggcccac accgggtgca tgcttagact caccttctgc agtgctaata
      661 tcatcaacca ttacttgtgt gacatactcc ccctcctcca gctttcctgc accagcacct
      721 atgtcaacga ggtggttgtt ctcattgttg tgggtactaa tatcacggta cccagttgta
      781 ccatcctcat ttcttatgtt ttcattgtca ctagcattct tcatatcaaa tccactcaag
      841 gaagatcaaa agccttcagt acttgtagct ctcatgtcat tgctctgtct ctgttttttg
      901 ggtcagcggc attcatgtat attaaatatt cttctggatc tatggagcag ggaaaagttt
      961 cttctgtttt ctacactaat gtggtgccca tgctcaatcc cctcatctac agtttgagga
     1021 acaaggatgt caaagttgca ctgaggaaag ctctgattaa aattcagagg agaaatatat
     1081 tctaattaga agc
//
