LOCUS       NM_001079935            1696 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 7 subfamily E member 24
            (OR7E24), transcript variant 1, mRNA.
ACCESSION   NM_001079935 NR_002146
VERSION     NM_001079935.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1696)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1696)
  AUTHORS   Grimwood,J., Gordon,L.A., Olsen,A., Terry,A., Schmutz,J.,
            Lamerdin,J., Hellsten,U., Goodstein,D., Couronne,O.,
            Tran-Gyamfi,M., Aerts,A., Altherr,M., Ashworth,L., Bajorek,E.,
            Black,S., Branscomb,E., Caenepeel,S., Carrano,A., Caoile,C.,
            Chan,Y.M., Christensen,M., Cleland,C.A., Copeland,A., Dalin,E.,
            Dehal,P., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Garcia,C., Georgescu,A.M., Glavina,T., Gomez,M.,
            Gonzales,E., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Ho,I.,
            Huang,W., Israni,S., Jett,J., Kadner,K., Kimball,H., Kobayashi,A.,
            Larionov,V., Leem,S.H., Lopez,F., Lou,Y., Lowry,S., Malfatti,S.,
            Martinez,D., McCready,P., Medina,C., Morgan,J., Nelson,K.,
            Nolan,M., Ovcharenko,I., Pitluck,S., Pollard,M., Popkie,A.P.,
            Predki,P., Quan,G., Ramirez,L., Rash,S., Retterer,J., Rodriguez,A.,
            Rogers,S., Salamov,A., Salazar,A., She,X., Smith,D., Slezak,T.,
            Solovyev,V., Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N.,
            Wagner,M., Wheeler,J., Wu,K., Xie,G., Yang,J., Dubchak,I.,
            Furey,T.S., DeJong,P., Dickson,M., Gordon,D., Eichler,E.E.,
            Pennacchio,L.A., Richardson,P., Stubbs,L., Rokhsar,D.S.,
            Myers,R.M., Rubin,E.M. and Lucas,S.M.
  TITLE     The DNA sequence and biology of human chromosome 19
  JOURNAL   Nature 428 (6982), 529-535 (2004)
   PUBMED   15057824
REFERENCE   3  (bases 1 to 1696)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   4  (bases 1 to 1696)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
REFERENCE   5  (bases 1 to 1696)
  AUTHORS   Goto,T., Salpekar,A. and Monk,M.
  TITLE     Expression of a testis-specific member of the olfactory receptor
            gene family in human primordial germ cells
  JOURNAL   Mol Hum Reprod 7 (6), 553-558 (2001)
   PUBMED   11385110
REFERENCE   6  (bases 1 to 1696)
  AUTHORS   Vanderhaeghen,P., Schurmans,S., Vassart,G. and Parmentier,M.
  TITLE     Molecular cloning and chromosomal mapping of olfactory receptor
            genes expressed in the male germ line: evidence for their wide
            distribution in the human genome
  JOURNAL   Biochem Biophys Res Commun 237 (2), 283-287 (1997)
   PUBMED   9268701
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC006271.2.
            
            On Aug 7, 2020 this sequence version replaced NM_001079935.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC146920.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000456448.3/ ENSP00000387523.1
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1696              AC006271.2         61049-62744
FEATURES             Location/Qualifiers
     source          1..1696
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.2"
     gene            1..1696
                     /gene="OR7E24"
                     /gene_synonym="HSHT2; OR19-8; OR7E24P; OR7E24Q"
                     /note="olfactory receptor family 7 subfamily E member 24"
                     /db_xref="GeneID:26648"
                     /db_xref="HGNC:HGNC:8396"
     exon            1..1696
                     /gene="OR7E24"
                     /gene_synonym="HSHT2; OR19-8; OR7E24P; OR7E24Q"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..1134
                     /gene="OR7E24"
                     /gene_synonym="HSHT2; OR19-8; OR7E24P; OR7E24Q"
                     /note="isoform 1 is encoded by transcript variant 1;
                     olfactory receptor 7E24; olfactory receptor OR19-14"
                     /codon_start=1
                     /product="olfactory receptor 7E24 isoform 1"
                     /protein_id="NP_001073404.1"
                     /db_xref="CCDS:CCDS45955.1"
                     /db_xref="GeneID:26648"
                     /db_xref="HGNC:HGNC:8396"
                     /translation="MSYFPILFFFFLKRCPSYTEPQNLTGVSEFLLLGLSEDPELQPV
                     LAGLFLSMYLVTVLGNLLIILAVSSDSHLHTPMYFFLSNLSLADIGFTSTTVPKMIVD
                     MQTHSRVISYEGCLTQMSFFVLFACMDDMLLSVMAYDRFVAICHPLHYRIIMNPRLCG
                     FLILLSFFISLLDSQLHNLIMLQLTCFKDVDISNFFCDPSQLLHLRCSDTFINEMVIY
                     FMGAIFGCLPISGILFSYYKIVSPILRVPTSDGKYKAFSTCGSHLAVVCLFYGTGLVG
                     YLSSAVLPSPRKSMVASVMYTVVTPMLNPFIYSLRNKDIQSALCRLHGRIIKSHHLHP
                     FCYMG"
ORIGIN      
        1 tgggtttgtc acaactgaga actattgctg agggtgtata atcctatgtg aaaacttaat
       61 ttcttaattg cttgtatcca aaatatagac acagtgctag atgctggttt acttatgtcc
      121 tattttccaa ttctcttttt ttttttcctc aaaaggtgtc cgagctacac agagccacag
      181 aatctcacag gtgtctcaga attcctcctc ctgggactct cagaggatcc agaactgcag
      241 ccggtcctcg ctgggctgtt cctgtccatg tacctggtca cggtgctggg gaacctgctc
      301 atcatcctgg ctgtcagctc tgactcccac ctccacaccc ccatgtactt cttcctctcc
      361 aacctgtcct tggctgacat cggtttcacc tccaccacgg tccccaagat gattgtggac
      421 atgcaaactc acagcagagt catctcctat gaaggctgcc tgactcagat gtcttttttt
      481 gtcctttttg catgtatgga tgacatgctc ctgagtgtga tggcctatga ccggtttgtg
      541 gccatctgtc accccctgca ctaccgaatc atcatgaacc cacgcctctg tggcttctta
      601 atcttgttgt ctttttttat tagtcttttg gactcccagt tgcacaattt gattatgtta
      661 cagctcacct gcttcaagga tgtggacatt tctaatttct tctgtgaccc ttctcaactc
      721 ctccacctta ggtgttccga caccttcatc aatgaaatgg tcatatattt catgggtgcc
      781 atatttggct gtctccctat ctcagggatc cttttctctt actataaaat tgtttccccc
      841 attctgagag ttccaacatc agatgggaag tataaagcct tctccacctg tggctctcac
      901 ctggcagttg tttgcttatt ttatggaaca gggcttgtag ggtacctcag ttcagctgtg
      961 ttaccatccc ccaggaagag tatggtggct tcagtgatgt acactgtggt cacccccatg
     1021 ctgaacccct tcatctacag cctgaggaac aaggacattc aaagtgccct gtgcaggctg
     1081 catggcagaa tcatcaaatc tcatcatctc catccttttt gttatatggg atagaaatgg
     1141 cagcaaaatt taacacctag gcctgcaaat tctgcctcct tggtcacatt attttggttg
     1201 cttgatggct ttcattcctc tctgggtttc gtatgtgaat attgcttgct ttgttttgtc
     1261 tttaattgca atgggtgagt attctggtat cctttgttca tcatacacat catgaatgat
     1321 tccaatatac ctagacagcc tcctttagta tctgtgcaat gaccttgata tccaggtgca
     1381 atcacaatct tttctgatag acttgaaatc ctcacttaac tttgtcaaga ggtttttgga
     1441 aactgcaact ttaaaaaaaa agcgcagcag gtcctgaaat aagttcattt tgttcaatgt
     1501 tgtttagttt taattttggt gagaaatgaa taaattggtt tcatggttca tcgttttgct
     1561 tgaattgtgg tttctaattt tctgtggagg atgttaagtg aggacttatc gtacttcgta
     1621 tttacctccc tttctacagt tcctgtgtaa tttctgtcca aatcgcatct aggaaatcac
     1681 tttaggcagc ttacgt
//
