LOCUS       NM_012377                960 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 7 subfamily C member 2
            (OR7C2), mRNA.
ACCESSION   NM_012377
VERSION     NM_012377.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 960)
  AUTHORS   Kim,R.N., Kim,A., Kim,D.W., Choi,S.H., Kim,D.S., Nam,S.H., Kang,A.,
            Kim,M.Y., Park,K.H., Yoon,B.H., Lee,K.S. and Park,H.S.
  TITLE     Analysis of indel variations in the human disease-associated genes
            CDKN2AIP, WDR66, USP20 and OR7C2 in a Korean population
  JOURNAL   J Genet 91 (1), e1-e11 (2012)
   PUBMED   22552337
  REMARK    GeneRIF: Analysis of indel variations in the human
            disease-associated genes CDKN2AIP, WDR66, USP20 and OR7C2 in a
            Korean population.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 960)
  AUTHORS   Grimwood,J., Gordon,L.A., Olsen,A., Terry,A., Schmutz,J.,
            Lamerdin,J., Hellsten,U., Goodstein,D., Couronne,O.,
            Tran-Gyamfi,M., Aerts,A., Altherr,M., Ashworth,L., Bajorek,E.,
            Black,S., Branscomb,E., Caenepeel,S., Carrano,A., Caoile,C.,
            Chan,Y.M., Christensen,M., Cleland,C.A., Copeland,A., Dalin,E.,
            Dehal,P., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Garcia,C., Georgescu,A.M., Glavina,T., Gomez,M.,
            Gonzales,E., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Ho,I.,
            Huang,W., Israni,S., Jett,J., Kadner,K., Kimball,H., Kobayashi,A.,
            Larionov,V., Leem,S.H., Lopez,F., Lou,Y., Lowry,S., Malfatti,S.,
            Martinez,D., McCready,P., Medina,C., Morgan,J., Nelson,K.,
            Nolan,M., Ovcharenko,I., Pitluck,S., Pollard,M., Popkie,A.P.,
            Predki,P., Quan,G., Ramirez,L., Rash,S., Retterer,J., Rodriguez,A.,
            Rogers,S., Salamov,A., Salazar,A., She,X., Smith,D., Slezak,T.,
            Solovyev,V., Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N.,
            Wagner,M., Wheeler,J., Wu,K., Xie,G., Yang,J., Dubchak,I.,
            Furey,T.S., DeJong,P., Dickson,M., Gordon,D., Eichler,E.E.,
            Pennacchio,L.A., Richardson,P., Stubbs,L., Rokhsar,D.S.,
            Myers,R.M., Rubin,E.M. and Lucas,S.M.
  TITLE     The DNA sequence and biology of human chromosome 19
  JOURNAL   Nature 428 (6982), 529-535 (2004)
   PUBMED   15057824
REFERENCE   4  (bases 1 to 960)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   5  (bases 1 to 960)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
REFERENCE   6  (bases 1 to 960)
  AUTHORS   Rouquier,S., Taviaux,S., Trask,B.J., Brand-Arpon,V., van den
            Engh,G., Demaille,J. and Giorgi,D.
  TITLE     Distribution of olfactory receptor genes in the human genome
  JOURNAL   Nat Genet 18 (3), 243-250 (1998)
   PUBMED   9500546
  REMARK    Erratum:[Nat Genet 1998 May;19(1):102]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC004659.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC110063.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000248072.3/ ENSP00000248072.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-960               AC004659.1         37792-38751
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.12"
     gene            1..960
                     /gene="OR7C2"
                     /gene_synonym="CIT-HSP-87M17; OR19-18; OR7C3"
                     /note="olfactory receptor family 7 subfamily C member 2"
                     /db_xref="GeneID:26658"
                     /db_xref="HGNC:HGNC:8374"
     CDS             1..960
                     /gene="OR7C2"
                     /gene_synonym="CIT-HSP-87M17; OR19-18; OR7C3"
                     /note="olfactory receptor, family 7, subfamily C, member
                     3; olfactory receptor OR19-22; olfactory receptor 7C3;
                     olfactory receptor 19-18"
                     /codon_start=1
                     /product="olfactory receptor 7C2"
                     /protein_id="NP_036509.1"
                     /db_xref="CCDS:CCDS12320.1"
                     /db_xref="GeneID:26658"
                     /db_xref="HGNC:HGNC:8374"
                     /translation="MERGNQTEVGNFLLLGFAEDSDMQLLLHGLFLSMYLVTIIGNLL
                     IILTISSDSHLHTPMYFFLSNLSFADICFTSTTVPKMLVNIQTQSKMITFAGCLTQIF
                     FFIAFGCLDNLLLTMTAYDRFVAICYPLHYTVIMNPRLCGLLVLGSWCISVMGSLLET
                     LTILRLSFCTNMEIPHFFCDPSEVLKLACSDTFINNIVMYFVTIVLGVFPLCGILFSY
                     SQIFSSVLRVSARGQHKAFSTCGSHLSVVSLFYGTGLGVYLSSAVTPPSRTSLAASVM
                     YTMVTPMLNPFIYSLRNKDMKGSLGRLLLRATSLKEGTIAKLS"
     exon            1..960
                     /gene="OR7C2"
                     /gene_synonym="CIT-HSP-87M17; OR19-18; OR7C3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggaaagag gaaaccaaac agaagttgga aactttctcc tcctgggatt cgcagaggac
       61 tctgacatgc agcttctcct ccatgggctg ttcctctcca tgtacctggt taccatcatc
      121 ggaaacctgc tcatcatcct gaccatcagt tcagactccc acctccacac ccccatgtac
      181 ttcttcctct ccaacctgtc ctttgctgac atctgtttca catccacgac tgtcccaaag
      241 atgctggtga atatccaaac acaaagcaaa atgatcactt ttgcaggctg cctcactcag
      301 atattttttt tcattgcatt tggatgcctg gacaatttgc tcctgaccat gacggcctat
      361 gaccgcttcg tggccatctg ttaccccctg cactacacgg tcatcatgaa cccccggctc
      421 tgtggactgc tggttctggg gtcctggtgc atcagtgtca tgggttcctt gcttgagacc
      481 ttgaccattt tgaggctgtc cttctgcaca aatatggaaa ttccgcactt tttttgtgat
      541 ccttccgaag tcctgaagct ggcctgttct gacaccttca tcaataacat cgtgatgtat
      601 tttgtgacca ttgtcctggg tgtttttcct ctctgtggaa tcctattctc ttattctcag
      661 attttctcct ccgtcctaag agtatctgcc agaggccagc acaaagcctt ttccacctgt
      721 ggttcccacc tctcagtggt cagcttgttc tatggcactg gccttggggt ctatctcagt
      781 tctgcagtta caccaccttc taggacaagt ctggcagcct cggtgatgta caccatggtc
      841 acccccatgc tgaacccctt catctacagc ctgaggaaca aggacatgaa ggggtcactg
      901 gggagactcc tcctcagggc aacgtctctc aaagagggga ccattgctaa gctctcatga
//
