LOCUS       NM_030901               3639 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 7 subfamily A member 17
            (OR7A17), mRNA.
ACCESSION   NM_030901
VERSION     NM_030901.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3639)
  AUTHORS   Kim,H., Park,S.H., Oh,S.W., Kwon,K., Park,S.J., Yu,E., Yang,S.,
            Park,J.Y., Choi,S., Yang,S., Han,S.B., Song,M., Cho,J.Y. and Lee,J.
  TITLE     Olfactory Receptor OR7A17 Expression Correlates with All-Trans
            Retinoic Acid (ATRA)-Induced Suppression of Proliferation in Human
            Keratinocyte Cells
  JOURNAL   Int J Mol Sci 22 (22), 12304 (2021)
   PUBMED   34830183
  REMARK    GeneRIF: Olfactory Receptor OR7A17 Expression Correlates with
            All-Trans Retinoic Acid (ATRA)-Induced Suppression of Proliferation
            in Human Keratinocyte Cells.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3639)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 3639)
  AUTHORS   Grimwood,J., Gordon,L.A., Olsen,A., Terry,A., Schmutz,J.,
            Lamerdin,J., Hellsten,U., Goodstein,D., Couronne,O.,
            Tran-Gyamfi,M., Aerts,A., Altherr,M., Ashworth,L., Bajorek,E.,
            Black,S., Branscomb,E., Caenepeel,S., Carrano,A., Caoile,C.,
            Chan,Y.M., Christensen,M., Cleland,C.A., Copeland,A., Dalin,E.,
            Dehal,P., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Garcia,C., Georgescu,A.M., Glavina,T., Gomez,M.,
            Gonzales,E., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Ho,I.,
            Huang,W., Israni,S., Jett,J., Kadner,K., Kimball,H., Kobayashi,A.,
            Larionov,V., Leem,S.H., Lopez,F., Lou,Y., Lowry,S., Malfatti,S.,
            Martinez,D., McCready,P., Medina,C., Morgan,J., Nelson,K.,
            Nolan,M., Ovcharenko,I., Pitluck,S., Pollard,M., Popkie,A.P.,
            Predki,P., Quan,G., Ramirez,L., Rash,S., Retterer,J., Rodriguez,A.,
            Rogers,S., Salamov,A., Salazar,A., She,X., Smith,D., Slezak,T.,
            Solovyev,V., Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N.,
            Wagner,M., Wheeler,J., Wu,K., Xie,G., Yang,J., Dubchak,I.,
            Furey,T.S., DeJong,P., Dickson,M., Gordon,D., Eichler,E.E.,
            Pennacchio,L.A., Richardson,P., Stubbs,L., Rokhsar,D.S.,
            Myers,R.M., Rubin,E.M. and Lucas,S.M.
  TITLE     The DNA sequence and biology of human chromosome 19
  JOURNAL   Nature 428 (6982), 529-535 (2004)
   PUBMED   15057824
REFERENCE   4  (bases 1 to 3639)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   5  (bases 1 to 3639)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
REFERENCE   6  (bases 1 to 3639)
  AUTHORS   Parmentier,M., Libert,F., Schurmans,S., Schiffmann,S., Lefort,A.,
            Eggerickx,D., Ledent,C., Mollereau,C., Gerard,C., Perret,J. et al.
  TITLE     Expression of members of the putative olfactory receptor gene
            family in mammalian germ cells
  JOURNAL   Nature 355 (6359), 453-455 (1992)
   PUBMED   1370859
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC002988.1 and AC005255.1.
            
            On Aug 7, 2020 this sequence version replaced NM_030901.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641113.1/ ENSP00000493283.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-192               AC002988.1         31737-31928         c
            193-290             AC002988.1         27570-27667         c
            291-968             AC002988.1         26670-27347         c
            969-3639            AC005255.1         91673-94343         c
FEATURES             Location/Qualifiers
     source          1..3639
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.12"
     gene            1..3639
                     /gene="OR7A17"
                     /gene_synonym="BC85395_4; HTPCRX19"
                     /note="olfactory receptor family 7 subfamily A member 17"
                     /db_xref="GeneID:26333"
                     /db_xref="HGNC:HGNC:8363"
     exon            1..192
                     /gene="OR7A17"
                     /gene_synonym="BC85395_4; HTPCRX19"
                     /inference="alignment:Splign:2.1.0"
     exon            193..290
                     /gene="OR7A17"
                     /gene_synonym="BC85395_4; HTPCRX19"
                     /inference="alignment:Splign:2.1.0"
     exon            291..3639
                     /gene="OR7A17"
                     /gene_synonym="BC85395_4; HTPCRX19"
                     /inference="alignment:Splign:2.1.0"
     CDS             487..1416
                     /gene="OR7A17"
                     /gene_synonym="BC85395_4; HTPCRX19"
                     /note="olfactory receptor OR19-20"
                     /codon_start=1
                     /product="olfactory receptor 7A17"
                     /protein_id="NP_112163.1"
                     /db_xref="CCDS:CCDS12319.1"
                     /db_xref="GeneID:26333"
                     /db_xref="HGNC:HGNC:8363"
                     /translation="MEPENDTGISEFVLLGLSEEPELQPFLFGLFLSMYLVTVLGNLL
                     IILATISDSHLHTPMYFFLSNLSFADICFISTTIPKMLINIQTQSRVITYAGCITQMC
                     FFVLFGGLDSLLLAVMAYDRFVAICHPLHYTVIMNPRLCGLLVLASWMIAALNSLSQS
                     LMVLWLSFCTDLEIPHFFCELNQVIHLACSDTFLNDMGMYFAAGLLAGGPLVGILCSY
                     SKIVSSIRAISSAQGKYKAFSTCASHLSVVSLFCCTGLGVYLTSAATHNSHTSATASV
                     MYTVATPMLNPFIYSLRNKDIKRALKMSFRGKQ"
ORIGIN      
        1 agcatatgca accttgggct ggaaatgaca tggtggtttc atttggagtc cttagtctgg
       61 ctcaagtata gatgatgctt caacttttcc tgatgccttg tcttgagaca gagattccat
      121 ctccaccatc aacctgctag agaggaattt acacttctcc atggagacct tcctttcaga
      181 aaactcagta ggcatggtga atatagttca tgatgatata ttgaattatt ggaaaatgcc
      241 aagaaaatgg atgttaagtg ttctcgccac aagaatgatg actatatgag tcacattgaa
      301 aagatgcaac caagcctggg cacaatggct tatgcctata atctcagcac ttttgtaggc
      361 tgaagtggga ggatcgcatg agtccaggag gttcagacca gcgttggcaa cagagtgaga
      421 gaccctgtct atgttaataa ataaataaat aaataaataa ataaataaat aaatagaaaa
      481 aaaaagatgg aaccagagaa tgacacaggg atttcagaat ttgttcttct gggactttct
      541 gaggaaccag aattgcagcc cttcctcttt gggctgtttc tgtccatgta cctggtcact
      601 gtgctcggga atctgctcat catcctggcc acaatctcag actcccacct ccacaccccc
      661 atgtacttct tcctctccaa cctgtccttt gcagacatct gtttcatctc cactacaatc
      721 ccaaagatgc tcattaacat ccagacacag agcagagtca tcacctatgc aggctgcatc
      781 acccagatgt gcttttttgt actttttgga gggttagaca gcttactcct ggctgtgatg
      841 gcctatgatc ggtttgtggc catctgtcat cctctgcact acacagtcat catgaaccct
      901 cggctctgtg gactcctggt tctggcatcc tggatgattg ctgccctgaa ttccttgtca
      961 caaagcttaa tggtattgtg gctgtccttc tgcacagact tggaaatccc ccactttttc
     1021 tgtgaactta atcaggtcat ccaccttgcc tgttctgaca cctttcttaa tgacatgggg
     1081 atgtattttg cagcagggct gctggctggt ggtccccttg tggggatcct ttgctcttac
     1141 tctaagatag tttcctccat acgtgcaatc tcatcagctc aggggaagta caaggcattt
     1201 tccacctgtg catcacacct ctcagttgtc tctttatttt gttgtacggg cctaggtgtg
     1261 taccttactt ctgctgcaac ccacaactca cacacaagtg caacagcctc agtgatgtac
     1321 actgtggcca cccccatgct gaaccccttt atctacagtc tgaggaataa agacataaag
     1381 agggctctga aaatgtcctt cagaggaaag caataaaagg gccatttttc aagaaataac
     1441 tgtgatttca gagctttaag tctcatactc agaaattgtg attcacgaat caggttgtga
     1501 aagtggaatt tgctccttct attttttctc agagtttcaa tttctttgat ctcaactgac
     1561 atagaattta atgtattcct ttataaagct ttccgctctc tgatatccaa tctttttttt
     1621 tttttttttt ttgtcatttt cctactttcc caatgttttt cccaaactag ggtcagaaac
     1681 aaggtggaga ttcctatttt tctcctacac ttgtgggttg cattagtcct gcagaatcaa
     1741 ttgcacctgg cagccataag gtcattaata taattttatt ttagataaat atctgagaag
     1801 acagtttttc actttgagct tattcctttc tccaccacca ccttaagtgt tcttcctggt
     1861 catgtaaact ttaccccaca cgagtgtgca ttttagctca tcatggcatt tattttttta
     1921 gatggagtct cgctctgtca cccaggctga agtgcagtgg catcatctca gctcactgca
     1981 acctctgcct cctgggttca agcaattctc ctgcctcagc ctcccaagga gctgggatta
     2041 caggcatgta ccaccatgcc cggctaattt ttgtattttt agtagggaag gggtttcacc
     2101 atgttggcca ggctggtctc gaactcctac cctcagggga tccgcctgcc tcggcccccc
     2161 aaagtgctgt catcatggca ttttatccta ctcattaggg tcctgtcctc tattcagttc
     2221 agtgtccacc gtgcctgctc aattccctgg aaagagtaag aaggtaaaaa tttcctatca
     2281 agtgcaggca cggtggctca ggcctgtaat cccagcactt tgggaggcca aggcgggcgg
     2341 atcacctgag gtagggagtt ggagaccagg ctgaccaaca gggagaaacc ccgtctctac
     2401 caaaaataca aaattagctg ggcgtggtgg cgcatgcctg taatcccagc tacgcaggag
     2461 actgaggcag gagaatggtt tgaacccggg agacggaggt tgcagtgagc cgagatcaca
     2521 gcattgccct ccagtctggg caacaagagc gaaactccat ctcaaaaaaa aaaaaattgc
     2581 ctatcaaatt cacacttcaa gtgtagtctg cacagaaaaa taaatttgtg tgaatcaatt
     2641 gatttcatct ggacttagat tacaaaaaca cctgaaagaa tatggattaa aaaatttatt
     2701 cataactgaa agaataaatg cttaatgggg tgggtacccc attcaccatg atgtgattat
     2761 tatataacgc atgcctgtat caaaacatct catgtacccc ataagtatat acatctacta
     2821 tgtacccaca aaaatataaa agaaaaaaag atggagtaaa atttttggcc cggcatggtg
     2881 gctcacgcct gtaatcccag aactttggga ggctgaggca agtggattac ctgaagtcag
     2941 gagttcaaga ccaggctggc caacatggtg aaaccctgtc tctactaaaa atgcaaaaat
     3001 tagccgggca tggtggcaca tgcctgtaat cccagctact caggaggctg aggcaggaga
     3061 atcacttgaa cctgggaggt ggaggttgca gtgagctgag atcacaccac tgcactccag
     3121 cctgggtgac agagactcca tctcaaaaaa aaaaatcagt catacattga attgcattgg
     3181 gagatttgat ctgatgatat acatctactt atagaggctt ggtgcccatt tgtaatgagg
     3241 tttgttagtc caagggaagg atttggaatc acagtctatg taatttcatt atatcatttt
     3301 actgtttctg cttaaaaatt tacagtgcta cacacaaata agactccttc tgttgtcctg
     3361 cttaaaatct tccttttaaa atattgtgtc ttagccatta aaatgtaggt aagtgaacaa
     3421 tgtgtgtatt taacttatca tcagttcatt tgtctctttt atactctaac tctcttcaac
     3481 ccttataatc aaatgatgac tcacaaagga acctgaattt ctaaccagca ttggcttgga
     3541 gaatagagac ttgtgaatca gaatcacaat ttatatctac aaatacatac acgttctttc
     3601 aaaatattct agctccctag aagggaatct aataggtag
//
