LOCUS       NM_001005189            5128 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 6 subfamily Y member 1
            (OR6Y1), transcript variant 1, mRNA.
ACCESSION   NM_001005189 XM_372799
VERSION     NM_001005189.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5128)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5128)
  AUTHORS   van der Harst,P., Zhang,W., Mateo Leach,I., Rendon,A., Verweij,N.,
            Sehmi,J., Paul,D.S., Elling,U., Allayee,H., Li,X.,
            Radhakrishnan,A., Tan,S.T., Voss,K., Weichenberger,C.X.,
            Albers,C.A., Al-Hussani,A., Asselbergs,F.W., Ciullo,M., Danjou,F.,
            Dina,C., Esko,T., Evans,D.M., Franke,L., Gogele,M., Hartiala,J.,
            Hersch,M., Holm,H., Hottenga,J.J., Kanoni,S., Kleber,M.E.,
            Lagou,V., Langenberg,C., Lopez,L.M., Lyytikainen,L.P., Melander,O.,
            Murgia,F., Nolte,I.M., O'Reilly,P.F., Padmanabhan,S., Parsa,A.,
            Pirastu,N., Porcu,E., Portas,L., Prokopenko,I., Ried,J.S.,
            Shin,S.Y., Tang,C.S., Teumer,A., Traglia,M., Ulivi,S., Westra,H.J.,
            Yang,J., Zhao,J.H., Anni,F., Abdellaoui,A., Attwood,A., Balkau,B.,
            Bandinelli,S., Bastardot,F., Benyamin,B., Boehm,B.O., Cookson,W.O.,
            Das,D., de Bakker,P.I., de Boer,R.A., de Geus,E.J., de Moor,M.H.,
            Dimitriou,M., Domingues,F.S., Doring,A., Engstrom,G.,
            Eyjolfsson,G.I., Ferrucci,L., Fischer,K., Galanello,R.,
            Garner,S.F., Genser,B., Gibson,Q.D., Girotto,G., Gudbjartsson,D.F.,
            Harris,S.E., Hartikainen,A.L., Hastie,C.E., Hedblad,B., Illig,T.,
            Jolley,J., Kahonen,M., Kema,I.P., Kemp,J.P., Liang,L.,
            Lloyd-Jones,H., Loos,R.J., Meacham,S., Medland,S.E., Meisinger,C.,
            Memari,Y., Mihailov,E., Miller,K., Moffatt,M.F., Nauck,M.,
            Novatchkova,M., Nutile,T., Olafsson,I., Onundarson,P.T.,
            Parracciani,D., Penninx,B.W., Perseu,L., Piga,A., Pistis,G.,
            Pouta,A., Puc,U., Raitakari,O., Ring,S.M., Robino,A., Ruggiero,D.,
            Ruokonen,A., Saint-Pierre,A., Sala,C., Salumets,A., Sambrook,J.,
            Schepers,H., Schmidt,C.O., Sillje,H.H., Sladek,R., Smit,J.H.,
            Starr,J.M., Stephens,J., Sulem,P., Tanaka,T., Thorsteinsdottir,U.,
            Tragante,V., van Gilst,W.H., van Pelt,L.J., van Veldhuisen,D.J.,
            Volker,U., Whitfield,J.B., Willemsen,G., Winkelmann,B.R.,
            Wirnsberger,G., Algra,A., Cucca,F., d'Adamo,A.P., Danesh,J.,
            Deary,I.J., Dominiczak,A.F., Elliott,P., Fortina,P., Froguel,P.,
            Gasparini,P., Greinacher,A., Hazen,S.L., Jarvelin,M.R., Khaw,K.T.,
            Lehtimaki,T., Maerz,W., Martin,N.G., Metspalu,A., Mitchell,B.D.,
            Montgomery,G.W., Moore,C., Navis,G., Pirastu,M., Pramstaller,P.P.,
            Ramirez-Solis,R., Schadt,E., Scott,J., Shuldiner,A.R., Smith,G.D.,
            Smith,J.G., Snieder,H., Sorice,R., Spector,T.D., Stefansson,K.,
            Stumvoll,M., Tang,W.H., Toniolo,D., Tonjes,A., Visscher,P.M.,
            Vollenweider,P., Wareham,N.J., Wolffenbuttel,B.H., Boomsma,D.I.,
            Beckmann,J.S., Dedoussis,G.V., Deloukas,P., Ferreira,M.A.,
            Sanna,S., Uda,M., Hicks,A.A., Penninger,J.M., Gieger,C.,
            Kooner,J.S., Ouwehand,W.H., Soranzo,N. and Chambers,J.C.
  TITLE     Seventy-five genetic loci influencing the human red blood cell
  JOURNAL   Nature 492 (7429), 369-375 (2012)
   PUBMED   23222517
REFERENCE   3  (bases 1 to 5128)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL160283.10 and AL365440.13.
            
            On Aug 4, 2020 this sequence version replaced NM_001005189.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 both encode the same protein.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641622.1/ ENSP00000492894.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-140               AL160283.10        7074-7213           c
            141-485             AL160283.10        2001-2345           c
            486-5128            AL365440.13        122312-126954       c
FEATURES             Location/Qualifiers
     source          1..5128
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q23.1"
     gene            1..5128
                     /gene="OR6Y1"
                     /gene_synonym="OR1-11; OR6Y2"
                     /note="olfactory receptor family 6 subfamily Y member 1"
                     /db_xref="GeneID:391112"
                     /db_xref="HGNC:HGNC:14823"
     exon            1..140
                     /gene="OR6Y1"
                     /gene_synonym="OR1-11; OR6Y2"
                     /inference="alignment:Splign:2.1.0"
     exon            141..5128
                     /gene="OR6Y1"
                     /gene_synonym="OR1-11; OR6Y2"
                     /inference="alignment:Splign:2.1.0"
     CDS             1573..2550
                     /gene="OR6Y1"
                     /gene_synonym="OR1-11; OR6Y2"
                     /note="olfactory receptor OR1-11; olfactory receptor 6Y2"
                     /codon_start=1
                     /product="olfactory receptor 6Y1"
                     /protein_id="NP_001005189.1"
                     /db_xref="CCDS:CCDS30899.1"
                     /db_xref="GeneID:391112"
                     /db_xref="HGNC:HGNC:14823"
                     /translation="MTTIILEVDNHTVTTRFILLGFPTRPAFQLLFFSIFLATYLLTL
                     LENLLIILAIHSDGQLHKPMYFFLSHLSFLEMWYVTVISPKMLVDFLSHDKSISFNGC
                     MTQLYFFVTFVCTEYILLAIMAFDRYVAICNPLRYPVIMTNQLCGTLAGGCWFCGLMT
                     AMIKMVFIAQLHYCGMPQINHYFCDISPLLNVSCEDASQAEMVDFFLALMVIAIPLCV
                     VVASYAAILATILRIPSAQGRQKAFSTCASHLTVVILFYSMTLFTYARPKLMYAYNSN
                     KVVSVLYTVIVPLLNPIIYCLRNHEVKAALRKTIHCRGSGPQGNGAFSS"
ORIGIN      
        1 aaccagactt gcccagaaac tctctaggct tatgtacatt gttcttctct tggtctacat
       61 gatttcttct cttttctcag cgcaagctgg ccatctttga taaagctagg tgggaaaagg
      121 gttatattcc tgagaaaatg gaatctaaag ctgaaatcta agtgggaaga ggaaatggat
      181 agtatgggca gtagttttct ggctctgcaa cctcatgatc attccttaaa aaaaaaaaaa
      241 aaccatcccc tagttgtcct acatatttat gccataaaat agagctgttg agaaatgggg
      301 atcaagagtg actgtggctc tggagaagag cagaaaagag aattgaagca ataggacaca
      361 gagcaagact tgaaatggga aggtgtttag tatcaatggg tttgggaatg attatcagcc
      421 taacacaaaa agaggtcaca cattttgcta aattaatgaa cagaaatgca gaagagtcac
      481 taatagaatt cttgcttgtt ttctctgata ttactcccaa cagattacag tttttaaatt
      541 tattaccctt ggaaaagtcc cacggtcctc tccctttttt cattaacaat ggctgctgtt
      601 tgcaccagtt ttttgctgtt tttggcaggg gttgaagttg gggtggggga aactttgtgt
      661 ggggtggagt gtgtgttttt ttaaaaggag gaggagctat gtatgtgggg taagtaaagt
      721 agcctggaaa ggtcacagca aatatcatag gaactgaatt taaactctaa atcccatttg
      781 atgttcacaa aatgtgaacc ccattgtatt atccccattt tagaaataaa gtaactaata
      841 ttctaaaaga ttatgtggta ctctcactta gctatacaaa gacaaaagtt ggatttgaat
      901 gcacttttgt caaactccta agcaagcact ttatacaatg gattgtattg aagaaactat
      961 tacccttcat gttatccatt caattttgtt ctctgaaaag ctggtgaata attgcatcaa
     1021 acctgatttt gctgttaatc ctgtgggtat gctcaactat tgcttcattc aagcttaagc
     1081 acattgttag acacaagcaa gaacgttctc tccattttac agataagtgg ggtcatgcaa
     1141 ccactccaga gtcacccaaa ttgcccctag agaatgggta gttgggcctt ctttctcttc
     1201 tccatattca gcagatgggg atgttttgcc tgtagtgaaa gggtggtctg gagaccattt
     1261 atgtgcccaa aagtgatata ttggtaaagc acagaactgg gatttagaaa gttataaact
     1321 ctattttgta tgaccttgga caagttactg ctcttgagaa aatctgaaaa caagttaaaa
     1381 tataagctcc ctaaattcca tcttttctca aaagctttgg ttctcttcat aattcaagag
     1441 gcagtaagat aaaaaagcag aaacctccta ttgtgataaa tttgctggtg gtgggctcta
     1501 tcaatacaaa taaccataga ctagtgcttg tgtcatggaa ggaactgact ttgtctgtgc
     1561 ccacagccag tcatgaccac cataattctg gaagtagata atcatacagt gacaacacgt
     1621 ttcattcttc tggggtttcc aacacgacca gccttccagc ttctcttttt ctccattttc
     1681 ctggcaacct atctgctgac actgctggag aatcttctta tcatcttagc tatccacagt
     1741 gatgggcagc tgcataagcc catgtacttc ttcttgagcc acctctcctt cctggagatg
     1801 tggtatgtca cagtcatcag ccccaagatg cttgttgact tcctcagtca tgacaagagt
     1861 atttccttca atggctgcat gactcaactt tacttttttg tgacctttgt ctgcactgag
     1921 tacatccttc ttgctatcat ggcctttgac cgctatgtag ccatttgtaa tccactacgc
     1981 tacccagtca tcatgaccaa ccagctctgt ggcacactgg ctggaggatg ctggttctgt
     2041 ggactcatga ctgccatgat taagatggtt tttatagcac aacttcacta ctgtggcatg
     2101 cctcagatca atcactactt ttgtgatatc tctccactcc ttaacgtctc ctgtgaggat
     2161 gcctcacagg ctgagatggt ggacttcttc ttggccctca tggtcattgc tattcctctt
     2221 tgtgttgtgg tggcatccta cgctgctatc cttgccacca tcctcaggat cccttctgct
     2281 cagggccgcc aaaaggcatt ctccacctgt gcctcccacc tgaccgtcgt aattctcttc
     2341 tattccatga cacttttcac ctatgcccgt cccaaactca tgtatgccta caattccaac
     2401 aaagtggtat ctgttctcta cactgtcatt gttccactcc tcaaccccat catttactgt
     2461 ctgaggaacc atgaagtaaa ggcagccctc agaaagacca tacattgcag aggaagtggg
     2521 ccccagggaa atggggcttt cagtagttaa aaaatgtata gattcctttc aggcttgaac
     2581 tgagagatga tcactacaca ctttccccct cagtcttgtc tttggttatc ccccaatctc
     2641 cagtactgta acactgctct cctctgtgtg tgtgtgcatg tgtgtgtgtg tgtatacaca
     2701 atcatgactg gagaaacatg ttctcaagaa gtaacctctg gtatcaggct gagagacaag
     2761 ttttaaaatg ttagaaaagc tatttgaaat caggaagaaa cacagagaga gagacagaga
     2821 gagtgggtgg taggagggag gaaaggagga agatgaatac tttttccaca caacttatca
     2881 aaataaatgc catacaggac aaacaattaa atataaagaa taaaaccatc gttcatctct
     2941 cagatggtta gaaaagggtt tttaaacact ctatattgta gaagtaaaag aaaaagttca
     3001 acataaatta atgcctgtta ggcacagtgg cacatacctg tagtcccagc tactcaagag
     3061 actgaggcag gaggatcccc tgagtccagg aacttgggcc cagcctggtc aacataggga
     3121 gtccccaccc acttccctcc aaataacata aatgactaat ttgttaaggc gtttaaaaac
     3181 aaaagattaa gtttatacca aataacaaag tgaaaactat tactaatttt tattattaat
     3241 gttataataa catataccaa ccttaaatat taaaaaacac tttaaaataa acttataaaa
     3301 attaaactct caatggaaaa acaagttaag tatataaaca taattttaaa aataggtagt
     3361 tgttatgggc aaagttatgt cccactcctc cctccctcca aaaaagtatg ttgtcctaac
     3421 cccagtctct cagaatgtga ccatatttga aagtagggtt tttatagtgg taatcgagct
     3481 aaaatttgac tgctagggtg ggccctaaga caatatgact ggtgtcatta taaaaaggaa
     3541 aaatttggac acagacacac acagaggaaa gacaatgtgc acacacacag ggcagagagc
     3601 aaccatgttt ctgcagtaat gcatctataa gctaaggaag aagtattgct ggcaaacacc
     3661 agaagctaga agcagcaagg aaggatgtta gcctagagct gaaagagaga gagagagtat
     3721 ggccctccca agtactttat ttgtgattcc taagatcaaa aatactgaga cagtatttgg
     3781 tactttttaa tggcagccct aggaaactaa tactggagcc aataaacctc agcaattttt
     3841 aaaaagatat taaaaaacaa aaattgacaa atgggatgta attaaactga caagcttctg
     3901 cacagcaaaa gaaattatca acagagtgaa caaacaacct acagaatgaa aacatttttg
     3961 gcaaaccata caactgacaa aggtctaata ttcagcatct ataaggaact taaacatatt
     4021 tacaagatga aaacaaacaa ctccatttaa aagtgggcaa aggatgtgaa cagacacttt
     4081 tcaaaagaaa acatacatgc agccaacaat catatgaaaa aaaggctcac tgatcattag
     4141 agaaatgaaa atcgaatcca caatgagtgg ttttatttta ttttatttta ttttattatt
     4201 attatacttt aagttttagg gtacatgtgc acaacgtgca ggtttgttac atatgtatac
     4261 atgtgacatg ttggtgtgct gcacccatta actcatcatt tagcattagg tatatctcct
     4321 aatgctatcc ctcccccctc cccccaccca caacattccc cggagtgtga tgttcctgtg
     4381 tccataataa tagccattct aactggtgtg aagtaacgtc taattttgtt accatctaac
     4441 accactccaa atggctatta ctaaaatgta aaaaaataac agatgctggt gaggttgtgg
     4501 agaaaaagga acacgtattc aatgttgttg ggagtgtata ttagttcaat ctatgtaaaa
     4561 gacagtgtaa cgattcctca aagacttaaa aacagaaata ccatttgacc cagcaatccc
     4621 attactgggt atatacctaa aggaatataa atcattctac tataaagaca catgcacatg
     4681 tatgtttatt gcagcactat ttacaatagc gaagacatgg aaccaaccac aatgcccatc
     4741 aataatagac tggataaaga aaatgtgcta catatacaac atgaaatact atgcagccat
     4801 aaaaaaaaat tagatcatgt cctttccggg aacatggatg ggactggagg ccatcacctt
     4861 tagcaaacta atgcaagaac agaaaaccaa ataccacata ttctcacttg taagtaggag
     4921 ctaaatgatg agaactcttg gacacacagt agggaacaca gtaggggccc attagagggt
     4981 gcagggtggg aggaggtaga ggatcaggag aaataactaa tgggtaatag gcttgatacc
     5041 tgggtgacaa aataatctgt acaacaaacc cccataatac aagattacct atataataaa
     5101 cctacacatg tacccctgaa cttaaaat
//
