LOCUS       NM_001160325            3255 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 6 subfamily P member 1
            (OR6P1), mRNA.
ACCESSION   NM_001160325
VERSION     NM_001160325.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3255)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3255)
  AUTHORS   Menashe,I., Aloni,R. and Lancet,D.
  TITLE     A probabilistic classifier for olfactory receptor pseudogenes
  JOURNAL   BMC Bioinformatics 7, 393 (2006)
   PUBMED   16939646
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3255)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL160283.10.
            
            On Aug 21, 2020 this sequence version replaced NM_001160325.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641540.1/ ENSP00000492936.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               AL160283.10        23250-23388         c
            140-234             AL160283.10        19572-19666         c
            235-3255            AL160283.10        13414-16434         c
FEATURES             Location/Qualifiers
     source          1..3255
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q23.1"
     gene            1..3255
                     /gene="OR6P1"
                     /note="olfactory receptor family 6 subfamily P member 1"
                     /db_xref="GeneID:128366"
                     /db_xref="HGNC:HGNC:15036"
     exon            1..139
                     /gene="OR6P1"
                     /inference="alignment:Splign:2.1.0"
     exon            140..234
                     /gene="OR6P1"
                     /inference="alignment:Splign:2.1.0"
     exon            235..3255
                     /gene="OR6P1"
                     /inference="alignment:Splign:2.1.0"
     CDS             257..1210
                     /gene="OR6P1"
                     /note="seven transmembrane helix receptor; olfactory
                     receptor OR1-12"
                     /codon_start=1
                     /product="olfactory receptor 6P1"
                     /protein_id="NP_001153797.1"
                     /db_xref="CCDS:CCDS53391.1"
                     /db_xref="GeneID:128366"
                     /db_xref="HGNC:HGNC:15036"
                     /translation="MRNLSGGHVEEFVLVGFPTTPPLQLLLFVLFFAIYLLTLLENAL
                     IVFTIWLAPSLHRPMYFFLGHLSFLELWYINVTIPRLLAAFLTQDGRVSYVGCMTQLY
                     FFIALACTECVLLAVMAYDRYLAICGPLLYPSLMPSSLATRLAAASWGSGFFSSMMKL
                     LFISQLSYCGPNIINHFFCDISPLLNLTCSDKEQAELVDFLLALVMILLPLLAVVSSY
                     TAIIAAILRIPTSRGRHKAFSTCAAHLAVVVIYYSSTLFTYARPRAMYTFNHNKIISV
                     LYTIIVPFFNPAIYCLRNKEVKEAFRKTVMGRCHYPRDVQD"
     regulatory      2494..2499
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR6P1"
                     /note="hexamer: AATAAA"
     polyA_site      2518
                     /gene="OR6P1"
                     /note="major polyA site"
ORIGIN      
        1 gggcaaacca tacctgccca gaggcaaaag ttaatcagcc tattgacaaa tatcaaaagg
       61 cagggtatat gtgtgaatgt ggaagacagg caagcaaaga agtaggtgaa cttctgtgac
      121 aaattttgtt cttattcagg ttgcctgttg acgctgatgg tggtttcttt tgctgcttcc
      181 cacccttcac tccgttttcc aacaactttc ccacatccct caggactgac cctggcactc
      241 aagtggacag agagccatga gaaatttgag tggaggccat gtcgaggagt ttgtcttggt
      301 gggtttccct accacgcctc ccctccagct gctcctcttt gtcctttttt ttgcaattta
      361 ccttctgaca ttgttggaga atgcacttat tgtcttcaca atatggcttg ctccaagcct
      421 tcatcgtccc atgtactttt tccttggcca tctctctttc ctggagctat ggtacatcaa
      481 tgtcaccatt cctcggctct tggcagcctt tcttacccag gatggtagag tctcctacgt
      541 aggttgcatg acccaactgt acttctttat tgccttagcc tgtactgaat gtgtgctgtt
      601 ggcagttatg gcctatgatc gctacctggc catctgtgga cccctccttt accctagtct
      661 catgccttcc agtctggcca ctcgccttgc tgctgcctct tggggcagtg gcttcttcag
      721 ctccatgatg aagcttcttt ttatttccca attgtcctac tgtggaccca acattatcaa
      781 ccactttttc tgtgatattt ccccactact caacctcacc tgctctgaca aggagcaagc
      841 agagctagta gacttccttc tggccctggt gatgattcta ctccctctat tggctgtggt
      901 ttcatcatac actgccatca ttgcagccat cctgaggatc cctacgtcca ggggacgcca
      961 caaagccttt tccacttgtg ccgctcatct ggcagtggtt gttatctact actcctccac
     1021 tctcttcacc tatgcacggc cccgggccat gtacaccttc aaccacaaca agattatctc
     1081 tgtgctctac actatcattg taccattctt caacccagcc atctactgcc tgaggaacaa
     1141 ggaggtgaag gaggccttca ggaagacagt gatgggcaga tgtcactatc ctagggatgt
     1201 tcaggactga tatacaacag gtcttgggag aggtgaaaat agcagaatct taatagggcc
     1261 tcctcaagga atcagaatag gctttaaggg aacataaata taatttgcca acattttctc
     1321 taaatattgt ctgggacctt ctgatacaaa tgaaacttta tgaatcattt attttttaca
     1381 ggggttttca aactaaggtt ggactagcta cagaagaatc acctgggaat ttgttaaaat
     1441 acagattccc ccaaaaaaat atgtggagag tcttactgag tatgtgtgga atgtaaccct
     1501 gccgtgaata atattcaaaa cttcctggga attcctattt catagacagt ttgggattcc
     1561 ctagtctaga ccaagcccat tatttcgtaa gtgagaaaat ataatatgag aaaacaaggg
     1621 aacttactgg tggacatgcc aagaaaaaaa tttggtagac ttcagtgtaa caatttcaaa
     1681 gatccagatt ctcaaatccc actttcataa gaaactacac aagtaggtta taccccaaga
     1741 cctaatttca tatcatctta tctacaaaac tcatattcac tgaaagtcaa agcagagaga
     1801 gatgcagtgc tgatattcag ccatatattc ttgactcaat atggctaact atcctctcca
     1861 tctcccttct ttgaatctca ggggcatgta aagctggttg acctaacaaa tattgaccag
     1921 gtagtaggta aaatgttcta gaaagcttat atacagatct tctccttcgc tatggccagc
     1981 acctgtttta agtaattagt gccagggcta taccgatagt gaaatatttt aaattgtgtt
     2041 cctagtcaaa ggattgtaag aacagaaaat gccttcataa gaaagaagat tgaagagcca
     2101 tagataggat gcagatatct ctatggcaat tgggatgtct caggttcata gcctgaatca
     2161 taggtattct agcaagttcc tttgattttt ggaaagttac ttgaattgtt cagagaaatt
     2221 tttcttatct tgaatctagg ctcatttaca caaatttctg catattgaac caaattcaat
     2281 gattatttag atgtgggata tgtgaaacaa aataaatatg caataacaat aaatatgcat
     2341 attggaacaa attccagtaa acacggattg ttggtcagtg cacatttgcc tattccgaga
     2401 cagattttga gggagaaaaa gacatgtgtc catcaatgca agctacttta tcaacaatca
     2461 ttttagattt tccagtatta aaaacaaaat aacaataaaa gatctgatac ttaaaacagt
     2521 ttaagttgtt ttgttttcat aaaatttcta aatagcctta gaaacagctc tgaacatagc
     2581 tcaatttaca ttacattctc ctctcctttc atagaattat gagagacatg gagttcagaa
     2641 ttcagaccct agaacgagca aatttcaatt tgatcctggc tttactaata acaagttatg
     2701 tgatcatagg caagaaactt tacatctctg ctcttagttt ctctttgata ataaaaataa
     2761 taccctttcc atcatatggg cttgttgtga atattaaata aataacacat atgcgggcaa
     2821 agggttagca ttttttttct ctttcctttt ggataaattt gatcttggat taatttctag
     2881 ttctggttct ctagaaacct aataaacatt actacacaaa attacttatg gcacaaatta
     2941 tctctgagca gcaaatgacc tctggactgg gaggatgatg aatgtattaa ggatatctag
     3001 tgggaaataa tagcttcaag ctacttttgt aacttggcat gtcttttgag ggaattctag
     3061 aagctatgga tgcccatgaa attgttacaa gtgatatagg ctcttacagg gcttgaaaat
     3121 tccaagttaa ggtggactct gcaccccttg atgaaaatct tatgtccacc tacctgagct
     3181 aagactttaa atgacagagt ctattccttc aactgctttc aggacttcct ttctgtaaga
     3241 gaaactccta aaact
//
