LOCUS       NM_001005327            1844 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 6 subfamily K member 3
            (OR6K3), mRNA.
ACCESSION   NM_001005327
VERSION     NM_001005327.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1844)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1844)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL513205.8.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Aug 5, 2020 this sequence version replaced NM_001005327.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000368145.2/ ENSP00000357127.1
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                AL513205.8         26369-26406         c
            39-1844             AL513205.8         22013-23818         c
FEATURES             Location/Qualifiers
     source          1..1844
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q23.1"
     gene            1..1844
                     /gene="OR6K3"
                     /gene_synonym="OR1-18"
                     /note="olfactory receptor family 6 subfamily K member 3"
                     /db_xref="GeneID:391114"
                     /db_xref="HGNC:HGNC:15030"
     exon            1..38
                     /gene="OR6K3"
                     /gene_synonym="OR1-18"
                     /inference="alignment:Splign:2.1.0"
     exon            39..1844
                     /gene="OR6K3"
                     /gene_synonym="OR1-18"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..1003
                     /gene="OR6K3"
                     /gene_synonym="OR1-18"
                     /note="olfactory receptor OR1-18; seven transmembrane
                     helix receptor"
                     /codon_start=1
                     /product="olfactory receptor 6K3"
                     /protein_id="NP_001005327.2"
                     /db_xref="CCDS:CCDS30903.2"
                     /db_xref="GeneID:391114"
                     /db_xref="HGNC:HGNC:15030"
                     /translation="MESGNQSTVTEFIFTGFPQLQDGSLLYFFPLLFIYTFIIIDNLL
                     IFSAVRLDTHLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISEKKAISMTGCILQMY
                     FFHSLENSEGILLTTMAIDRYVAICNPLRYQMIMTPRLCAQLSAGSCLFGFLILLPEI
                     VMISTLPFCGPNQIHQIFCDLVPVLSLACTDTSMILIEDVIHAVTIIITFLIIALSYV
                     RIVTVILRIPSSEGRQKAFSTCAGHLMVFPIFFGSVSLMYLRFSDTYPPVLDTAIALM
                     FTVLAPFFNPIIYSLRNKDMNNAIKKLFCLQKVLNKPGG"
ORIGIN      
        1 cccaggcaga ctgaggagtc cctgtgtttt tggcaaaggt agctctacta gaaatatgga
       61 gagcggaaac caatcaacag tgactgaatt tatcttcact ggattccctc agcttcagga
      121 tggtagtctc ctgtacttct ttcctttact tttcatctat acttttatta tcattgataa
      181 cttattaatc ttctctgctg taaggctgga cacccatctc cacaacccca tgtataattt
      241 tatcagtata ttttcctttc tggagatctg gtacaccaca gccaccattc ccaagatgct
      301 ctccaacctc atcagtgaaa agaaggccat ctcaatgact ggctgcatct tgcagatgta
      361 tttcttccac tcacttgaaa actcagaggg gatcttgctg accaccatgg ccattgacag
      421 atacgttgcc atctgcaacc ctcttcgcta tcaaatgatc atgacccccc ggctctgtgc
      481 tcaactctct gcaggttcct gcctcttcgg tttccttatc ctgcttcccg agattgtgat
      541 gatttccaca ctgcctttct gtgggcccaa ccaaatccat cagatcttct gtgacttggt
      601 ccctgtgcta agcctggcct gtacagacac gtccatgatt ctgattgagg atgtgattca
      661 tgctgtgacc atcatcatta ccttcctaat cattgccctg tcctatgtaa gaattgtcac
      721 tgtgatattg aggattccct cttctgaagg gaggcaaaag gctttttcta cctgtgcagg
      781 ccacctcatg gtcttcccga tattctttgg cagtgtatca ctcatgtact tgcgtttcag
      841 cgacacttat ccaccagttt tggacacagc cattgcactg atgtttactg tacttgctcc
      901 attcttcaat cccatcattt atagcctgag aaacaaggac atgaacaatg cgattaaaaa
      961 actgttctgt cttcaaaaag tgttgaacaa gcctggaggt taatacagag ccacaggttc
     1021 ccttccgttg cttttgtttt gttttgtttt ttgagatgga gtttcactct tgttgcctgg
     1081 gctggagtgc aatggcatga tcttggctca ctgcaacctc cacctcctgg ttttgaacaa
     1141 ttctcctgcc tcagcctccc tagtagccgc gattacaggc atgcaccacc acacccagct
     1201 aatttttgta tttttagtgg agatggggtt tcactgtgtt ggtcaggctg gtcttgaact
     1261 cctgacctta ggtgatccaa actcctctgc ctcccaaaat gctgggatta cagctgtgag
     1321 ccaccgcatc tggccctttc cattgcttta atgtttgtct aacatattag aacatgagat
     1381 tactctatac ctagtgcttt gtcacactga aatttctgtc atcctaatta ttttccctat
     1441 acctagaaaa atatttatac tctctgtgtc atcgttataa aagttgctgt gcatatcatg
     1501 aggaacctta ttatgtggct gaataactgt agtttctttc ttctgaaatg ctgtggttaa
     1561 agaaaatttg tttgccactt tagagggtta gaactacaga gcttgagctt cagaagctga
     1621 caatgtgctc tgtggtagta tgtgtctatt taggtaacac atcttagaaa agtttttttg
     1681 tttaattatg agtcatggat tacctcattg gggttttcca gaaatagaga tctaagaaaa
     1741 agcccaaaca acatttaatt aagttatatc tttattttta gttatgtagt tacctattca
     1801 ttagaataat tacatgttta gtaagattag attattagta ctgc
//
