LOCUS       NM_001005497            4569 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 6 subfamily C member 75
            (OR6C75), mRNA.
ACCESSION   NM_001005497
VERSION     NM_001005497.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4569)
  AUTHORS   Goodbourn,P.T., Bosten,J.M., Bargary,G., Hogg,R.E.,
            Lawrance-Owen,A.J. and Mollon,J.D.
  TITLE     Variants in the 1q21 risk region are associated with a visual
            endophenotype of autism and schizophrenia
  JOURNAL   Genes Brain Behav 13 (2), 144-151 (2014)
   PUBMED   24152035
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125816.8.
            
            On Aug 3, 2020 this sequence version replaced NM_001005497.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641576.1/ ENSP00000493430.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-75                AC125816.8         78932-79006         c
            76-165              AC125816.8         78099-78188         c
            166-4569            AC125816.8         72702-77105         c
FEATURES             Location/Qualifiers
     source          1..4569
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.2"
     gene            1..4569
                     /gene="OR6C75"
                     /note="olfactory receptor family 6 subfamily C member 75"
                     /db_xref="GeneID:390323"
                     /db_xref="HGNC:HGNC:31304"
     exon            1..75
                     /gene="OR6C75"
                     /inference="alignment:Splign:2.1.0"
     exon            76..165
                     /gene="OR6C75"
                     /inference="alignment:Splign:2.1.0"
     exon            166..4569
                     /gene="OR6C75"
                     /inference="alignment:Splign:2.1.0"
     CDS             401..1339
                     /gene="OR6C75"
                     /codon_start=1
                     /product="olfactory receptor 6C75"
                     /protein_id="NP_001005497.1"
                     /db_xref="CCDS:CCDS31820.1"
                     /db_xref="GeneID:390323"
                     /db_xref="HGNC:HGNC:31304"
                     /translation="MRNSTAVTDFILLGLTSDPQWQVVLFIFLLVTYMLSVTGNLIII
                     TLTLSDPHLQTPMYFFLRNFSFLEISFTSVCIPRFLVTVVTGNRTISYNGCVAQLFFF
                     IFLGVTEFYLLAAMSYDRCMAICKPLHYTIIMSTRVCTLLVFSSWLAGFLIIFPPVML
                     LLQLDFCASNVIDHFICDSSPMLQLSCTNTHFLELMAFFLAVVTLMVTLTLVILSYTN
                     IIRTILKIPSMSQRKKAFSTCSSHMIVVSISYSSCIFMYIKTSARERVTLSKGVAVLN
                     TSVAPLLNPFIYTLRNKQVKQAFKSMVQKMIFSLNK"
ORIGIN      
        1 ctcggaaagc cactacatta gccttcattt caactaaaat ttgtatcaag gtaatacttt
       61 ttaaagcggc gatagggaat atactgaaac atttagaaga cagagatgta ttctgaaata
      121 tataaaaata taatgaagga aatacagaaa taattgattt ataagataga tgcatcagcg
      181 gatagctaga cacaatggaa tgttatccag cctcataaaa gaaggagata ctgccacact
      241 gccatttgtg acattacgga tgaacctgga aggcattatg gtaaatggaa agagccagac
      301 agaaaaaaaa taataatttt ctttactggt gtcatagttt tctggtttct tcacctattt
      361 tacagcgaaa atacagaata cttttctaaa gaaaaaaata atgagaaatt ccacagcagt
      421 aacagacttt attcttcttg gattgacaag tgacccacag tggcaggttg tacttttcat
      481 atttcttctt gttacctaca tgttaagtgt gactgggaac ctgatcatta tcaccctcac
      541 cctttcagat ccccatctgc agactcccat gtatttcttc cttcggaact tctcattcct
      601 ggaaatttca ttcacgtctg tctgcattcc cagattcctt gtcactgttg tgacaggaaa
      661 cagaaccatt tcttataatg ggtgtgtggc tcagctattt tttttcatct tcttgggggt
      721 gacagaattt taccttctgg ctgccatgtc ctatgaccgc tgcatggcca tctgcaaacc
      781 tcttcattac acaatcatca tgagcaccag agtgtgtacc cttcttgtct ttagctcctg
      841 gcttgcaggg tttctgatca tctttccacc agtaatgctt ctgctgcagt tggatttctg
      901 tgcctccaat gtaattgatc attttatctg tgactcttct ccaatgctgc agctctcttg
      961 cacaaacact cactttctag aactcatggc atttttttta gctgtggtaa cactgatggt
     1021 caccttgaca ttagttattc tctcctacac aaacatcatc cggacaattc tgaaaattcc
     1081 ttctatgagt caaaggaaaa aagccttttc cacttgctcc tcccatatga tagttgtctc
     1141 catctcttac agtagctgta tcttcatgta cattaagact tctgccagag aaagggtgac
     1201 tttaagcaaa ggagtagctg tgctcaatac ctcagtggct cctctcttga atcccttcat
     1261 atacacactg agaaataagc aagtgaagca agccttcaag agcatggtcc agaagatgat
     1321 tttttcttta aataaatgaa tgtgattatg taaaaaatgt acccccaaag gcaaagctga
     1381 atgaaaaact ctctaccctt ctctacatga actctttcta aacaccttat ttcacacttt
     1441 tagttagaca tagttacata tcatcaacac ttcttaatga aattagccta aaaaccaaga
     1501 tttagctctt ctaaactata tagaaagtgt tcgctctctc acctatgtaa ctaaatttta
     1561 ggtaaattaa taattactat ggtttattga gggatagcat tgggagatat acctaaggct
     1621 agatgacgag ttagtgggtg cagcgcacca gcatggcaca tgtatacata tgtaactaac
     1681 ctgcacaatg tgcacatgta ccttaaaact taaagtataa taaaaaataa taataaaata
     1741 aaggcaaaat agattcttca ttcataaaat agaggtagct ataaattaaa aacttactaa
     1801 aaccacattc aactatgaaa ttaattttat atgaaatgtt taaactatgt atcttaatta
     1861 atatatctaa aattttttct tcaatgtcac caggaaaaac atgttataaa actaaaagca
     1921 tcattaaaat gtctccttgt atttgtcaat aaaatgtagt taaaatgtgt gtaaacatta
     1981 aataaaagtg taagacaaat gtgcagagat attatctctg ttgtttgaat taaggctgta
     2041 ttactttttg tcttagcttt cctagaaaaa aagagcaaag cgtaatcaaa gagttgatat
     2101 tatttatctt atattttcct ttgataatat ttccttaaaa atagattatt taacagagaa
     2161 cttttctgtt tctgccaata ttttaaaaga aaaaccatga tctatgaagg caattcatat
     2221 ttgtgttcag attccttata ttgatacaaa attgccttac tactgatatg atgaagaaaa
     2281 tgacaaagta agagtctaca atggtgtgat actgcccttt tataaggtat tcggcgaatg
     2341 atgacgtggt ttattaatgt cttggttttt ccttttctag taaacctata atattttatt
     2401 tatctttcca ttgtctcctt cacaggtttc actcccctca cctatatcca agaaaatgac
     2461 ttttagaggt atttgagaac tgtaaaaaat gtgttcaagc ccacttccta tagttaatga
     2521 gtccctcaac tcccatgtat cattaagaaa attggttgtt gaatccagca gcacatcaaa
     2581 aagataattc accacgatca agtgggcttt aaacctggat gcaaggatgg tttaacatac
     2641 acgaatcaat aaatgtgatt caccacataa acagaactaa aaacaaaaac catatgatca
     2701 tctcaataga cacagaaaaa atagtcaata aatccaacat ccctttatga caaaaacact
     2761 caacaaacca cgcattgaag gaaaatagcc caaaataata acagccatct gtgacagacc
     2821 cacagccaat atcataataa actagcaaaa gttgtatgca ttcttcctga gaactggaac
     2881 aagacaagga tgtcccctct cagcactcct attcaacata gtactgaaag ccctagccag
     2941 agcaatcagg caagagagag aaatgaaagg catccaaata ggaaaagaag aagtcaaatt
     3001 atctccgttt actgaaaata taatcctgta cctaaaaaac tttaaaggtt cctccaaaaa
     3061 actcctaggc ctgataaact acttgagtaa agtttgagga tataaaatca acatagaaaa
     3121 gtcagtagca tttctataca ccaataacat tcaagctgag aaccaaataa aaaacgcaat
     3181 cttggctggg tgtggtggct catgcccgaa atctcagcac tttgggaggc caagcgggga
     3241 ggattgcttg agcccagaag tttaagacca gccttggcaa catagtgaga ctctgtctac
     3301 acaaaaaaat ttaaaaatta gctaagcatg gtagcataca cctgtggtcc cagctactca
     3361 agaagatgag gtgggagaat tgcttggacc ttggaggttg aggctgcagt gagctctcat
     3421 catgccactg cactccaccc tggacaacag agtgagaccc tgtctcaaaa aaataaataa
     3481 aagttgtcca aacatggtgg ctcacgcctg taatcccagc actttgagag gctgaggctg
     3541 gtggatcact tgaggccagg agttcaagac cagcctggac agcatagcaa gaccctatct
     3601 ctacttaaaa ataaaaaaac aagatgcctg taattccagc actttgggag gccaaggcag
     3661 gcaaattact tgagtacaag agttcaagac aagtctgagc aacatggtga aaccccaatc
     3721 tctacaaaaa atacaaaaat tagctggtca cgctggcatg cacctgtagt cccagctact
     3781 taagaggctg aggtggaaga atcgcttgag tacaggaggt ggaggctaca gtgagccaag
     3841 attgcaccac tgcactccag cctgggcgat agagcgaaac tctatctcga taaaataaaa
     3901 caaaataaaa aagttatttt aaaatttcta aaacaagaaa agaaaattgg ctgtcttggg
     3961 acagtagcta tgaatctgac tagatacagg ataaatggat tttagtttga ttccttgatt
     4021 ttcagctttg tctgatatac aggtgaatgt aaagagctct acaggttttc taagtctgtg
     4081 acaaatactt ttttttatag atgtgagcgt ccttcagcac ttgtctattt cttaccattg
     4141 tgttttatgg aatggcatac ttttttttaa aacagattat aatataatat catcacaaaa
     4201 tgaaaattac atgataatga ttacatgatt atttcattat gaattcttta ttgtggcaat
     4261 ttgtaaagaa atgagacatt gtaagtttgc ttttattaag attacaacaa gtaagcagaa
     4321 atgcaaaagt gaaaatcagg agtgtggaaa caacatgcaa acgttaacta agtgaagata
     4381 aagtatatat acatatacaa ctacatgata gatagataga taaagagaga tagagggaaa
     4441 gagagggaaa gaagagaaac tggaaaatta gagagtaagg gaaagtaaat tttcttaatc
     4501 cacaaaaact tatctgaaga agttgattct aatgttcaat aaatgtaaac ccatgaaaat
     4561 cactatgaa
//
