LOCUS       NM_001005493            1521 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 6 subfamily C member 6
            (OR6C6), mRNA.
ACCESSION   NM_001005493
VERSION     NM_001005493.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1521)
  AUTHORS   Goodbourn,P.T., Bosten,J.M., Bargary,G., Hogg,R.E.,
            Lawrance-Owen,A.J. and Mollon,J.D.
  TITLE     Variants in the 1q21 risk region are associated with a visual
            endophenotype of autism and schizophrenia
  JOURNAL   Genes Brain Behav 13 (2), 144-151 (2014)
   PUBMED   24152035
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122684.3.
            
            On Aug 3, 2020 this sequence version replaced NM_001005493.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000358433.3/ ENSP00000351211.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-251               AC122684.3         41272-41522
            252-1521            AC122684.3         42584-43853
FEATURES             Location/Qualifiers
     source          1..1521
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.2"
     gene            1..1521
                     /gene="OR6C6"
                     /note="olfactory receptor family 6 subfamily C member 6"
                     /db_xref="GeneID:283365"
                     /db_xref="HGNC:HGNC:31293"
     exon            1..251
                     /gene="OR6C6"
                     /inference="alignment:Splign:2.1.0"
     exon            252..1521
                     /gene="OR6C6"
                     /inference="alignment:Splign:2.1.0"
     CDS             277..1221
                     /gene="OR6C6"
                     /codon_start=1
                     /product="olfactory receptor 6C6"
                     /protein_id="NP_001005493.1"
                     /db_xref="CCDS:CCDS31817.1"
                     /db_xref="GeneID:283365"
                     /db_xref="HGNC:HGNC:31293"
                     /translation="MKNKSMEIEFILLGLTDDPQLQIVIFLFLFLNYTLSLMGNLIII
                     ILTLLDPRLKTPMYFFLRNFSFLEVIFTTVCIPRFLITIVTRDKTISYNNCATQLFFI
                     LLPGVTEFYLLAAMSYDRYVAICKPLHYPIIMSSKVCYQLVLSSWVTGFLIIFPPLVM
                     GLKLDFCASKTIDHFMCETSPILQISCTDTHVLELMSFTLAVVTLVVTLVLVILSYTC
                     IIKTILKFSSAQQRNKAFSTCTSHMIVVSMTYGSCIFMYIKPSAKERVTVSKGVALLY
                     TSIAPLLNPFIYTLRNQQVKEVFWDVLQKNLCFSKRPF"
ORIGIN      
        1 gatagatgtc cattaaaatt attaatatct gagtatcaat ctttatagtg aggatgaagt
       61 tgaggaaatg tggaaattct ctacagaaac acaatacgta cacattgcct ctccccacaa
      121 aaatcattgg taataaatgt gcctattgga taataaaatg tggtcataaa atgagtagaa
      181 ttgtcactaa ttatgttagc atgcatctct tccgtgcaca cagaaagaaa tgaataatag
      241 atccaaaaaa gatttgataa ggatcacaaa agagaaatga agaacaaatc aatggaaata
      301 gagttcattc tcctaggatt gacagatgac ccacagttgc aaattgtgat tttcctgttt
      361 ctatttctca actacacctt gagcctgatg gggaacttaa tcatcatcat cctcaccctg
      421 ctggatcccc ggctcaagac gccaatgtat ttctttctcc gtaatttctc ctttttggaa
      481 gtaatattca caacagtgtg tattcctaga ttcttgataa ccattgtgac tagagacaaa
      541 accatttctt ataataattg tgcaactcaa ttatttttta tccttttacc gggagttact
      601 gagttttacc tcctggctgc catgtcctat gaccgctacg ttgccatctg caaaccactg
      661 cattatccaa tcattatgag cagcaaagtc tgctaccaac ttgtacttag ctcttgggta
      721 actggattct taatcatatt tcccccattg gtcatgggac tcaagctgga tttttgtgct
      781 tccaaaacta ttgaccactt tatgtgtgaa acttctccta ttctgcagat ctcctgcaca
      841 gatacccatg tcctagaatt gatgtctttt accttagctg tggtgacact tgtggtcaca
      901 ctggtattag tgattctctc ttacacttgc attattaaga ccattctgaa attctcttct
      961 gcacagcaaa ggaacaaagc attttccacc tgtacttccc acatgattgt tgtctccatg
     1021 acatacggta gctgtatctt tatgtatatt aaaccatctg caaaagaaag agtgactgta
     1081 tccaaaggtg tagctttgct ctatacctca attgcccctt tactaaatcc cttcatttat
     1141 actctcagaa accagcaggt gaaagaagtc ttctgggatg tattacaaaa gaatttgtgt
     1201 ttttctaaaa gaccatttta agaatctgct acaaattaca actttaccat aaaaactgga
     1261 aaacggcctg gcatggtggc tcatgcctgt aatcacagca ctttgggagg ctgaggaggg
     1321 tggttacctg aggtcaggag ttcgagacca gcctggccaa catggtgaaa ccccgtctct
     1381 acttaaaagt acaaaaatta gctgggcgtg gtggagagtg cctgtaatcc cagctactca
     1441 ggagtctgag gcaagagaat agcttgaact cgggaggtgg aggttgcagt gagcccagat
     1501 ggtgccactg cacaccagct t
//
