LOCUS       NM_001388498            1042 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 6 subfamily C member 3
            (OR6C3), transcript variant 2, mRNA.
ACCESSION   NM_001388498
VERSION     NM_001388498.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1042)
  AUTHORS   Goodbourn,P.T., Bosten,J.M., Bargary,G., Hogg,R.E.,
            Lawrance-Owen,A.J. and Mollon,J.D.
  TITLE     Variants in the 1q21 risk region are associated with a visual
            endophenotype of autism and schizophrenia
  JOURNAL   Genes Brain Behav 13 (2), 144-151 (2014)
   PUBMED   24152035
REFERENCE   2  (bases 1 to 1042)
  AUTHORS   Scherer,S.E., Muzny,D.M., Buhay,C.J., Chen,R., Cree,A., Ding,Y.,
            Dugan-Rocha,S., Gill,R., Gunaratne,P., Harris,R.A., Hawes,A.C.,
            Hernandez,J., Hodgson,A.V., Hume,J., Jackson,A., Khan,Z.M.,
            Kovar-Smith,C., Lewis,L.R., Lozado,R.J., Metzker,M.L.,
            Milosavljevic,A., Miner,G.R., Montgomery,K.T., Morgan,M.B.,
            Nazareth,L.V., Scott,G., Sodergren,E., Song,X.Z., Steffen,D.,
            Lovering,R.C., Wheeler,D.A., Worley,K.C., Yuan,Y., Zhang,Z.,
            Adams,C.Q., Ansari-Lari,M.A., Ayele,M., Brown,M.J., Chen,G.,
            Chen,Z., Clerc-Blankenburg,K.P., Davis,C., Delgado,O., Dinh,H.H.,
            Draper,H., Gonzalez-Garay,M.L., Havlak,P., Jackson,L.R.,
            Jacob,L.S., Kelly,S.H., Li,L., Li,Z., Liu,J., Liu,W., Lu,J.,
            Maheshwari,M., Nguyen,B.V., Okwuonu,G.O., Pasternak,S., Perez,L.M.,
            Plopper,F.J., Santibanez,J., Shen,H., Tabor,P.E., Verduzco,D.,
            Waldron,L., Wang,Q., Williams,G.A., Zhang,J., Zhou,J., Allen,C.C.,
            Amin,A.G., Anyalebechi,V., Bailey,M., Barbaria,J.A., Bimage,K.E.,
            Bryant,N.P., Burch,P.E., Burkett,C.E., Burrell,K.L., Calderon,E.,
            Cardenas,V., Carter,K., Casias,K., Cavazos,I., Cavazos,S.R.,
            Ceasar,H., Chacko,J., Chan,S.N., Chavez,D., Christopoulos,C.,
            Chu,J., Cockrell,R., Cox,C.D., Dang,M., Dathorne,S.R., David,R.,
            Davis,C.M., Davy-Carroll,L., Deshazo,D.R., Donlin,J.E., D'Souza,L.,
            Eaves,K.A., Simons,R., Emery-Cohen,A.J., Escotto,M., Flagg,N.,
            Forbes,L.D., Gabisi,A.M., Garza,M., Hamilton,C., Henderson,N.,
            Hernandez,O., Hines,S., Hogues,M.E., Huang,M., Idlebird,D.G.,
            Johnson,R., Jolivet,A., Jones,S., Kagan,R., King,L.M., Leal,B.,
            Lebow,H., Lee,S., LeVan,J.M., Lewis,L.C., London,P.,
            Lorensuhewa,L.M., Loulseged,H., Lovett,D.A., Lucier,A.,
            Lucier,R.L., Ma,J., Madu,R.C., Mapua,P., Martindale,A.D.,
            Martinez,E., Massey,E., Mawhiney,S., Meador,M.G., Mendez,S.,
            Mercado,C., Mercado,I.C., Merritt,C.E., Miner,Z.L., Minja,E.,
            Mitchell,T., Mohabbat,F., Mohabbat,K., Montgomery,B., Moore,N.,
            Morris,S., Munidasa,M., Ngo,R.N., Nguyen,N.B., Nickerson,E.,
            Nwaokelemeh,O.O., Nwokenkwo,S., Obregon,M., Oguh,M., Oragunye,N.,
            Oviedo,R.J., Parish,B.J., Parker,D.N., Parrish,J., Parks,K.L.,
            Paul,H.A., Payton,B.A., Perez,A., Perrin,W., Pickens,A.,
            Primus,E.L., Pu,L.L., Puazo,M., Quiles,M.M., Quiroz,J.B.,
            Rabata,D., Reeves,K., Ruiz,S.J., Shao,H., Sisson,I., Sonaike,T.,
            Sorelle,R.P., Sutton,A.E., Svatek,A.F., Svetz,L.A., Tamerisa,K.S.,
            Taylor,T.R., Teague,B., Thomas,N., Thorn,R.D., Trejos,Z.Y.,
            Trevino,B.K., Ukegbu,O.N., Urban,J.B., Vasquez,L.I., Vera,V.A.,
            Villasana,D.M., Wang,L., Ward-Moore,S., Warren,J.T., Wei,X.,
            White,F., Williamson,A.L., Wleczyk,R., Wooden,H.S., Wooden,S.H.,
            Yen,J., Yoon,L., Yoon,V., Zorrilla,S.E., Nelson,D.,
            Kucherlapati,R., Weinstock,G. and Gibbs,R.A.
  CONSRTM   Baylor College of Medicine Human Genome Sequencing Center Sequence
            Production Team
  TITLE     The finished DNA sequence of human chromosome 12
  JOURNAL   Nature 440 (7082), 346-351 (2006)
   PUBMED   16541075
REFERENCE   3  (bases 1 to 1042)
  AUTHORS   Rouquier,S., Blancher,A. and Giorgi,D.
  TITLE     The olfactory receptor gene repertoire in primates and mouse:
            evidence for reduction of the functional fraction in primates
  JOURNAL   Proc Natl Acad Sci U S A 97 (6), 2870-2874 (2000)
   PUBMED   10706615
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122684.3.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641740.2/ ENSP00000493380.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-62                AC122684.3         7034-7095           c
            63-1042             AC122684.3         5205-6184           c
FEATURES             Location/Qualifiers
     source          1..1042
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.2"
     gene            1..1042
                     /gene="OR6C3"
                     /gene_synonym="OST709"
                     /note="olfactory receptor family 6 subfamily C member 3"
                     /db_xref="GeneID:254786"
                     /db_xref="HGNC:HGNC:15437"
     exon            1..62
                     /gene="OR6C3"
                     /gene_synonym="OST709"
                     /inference="alignment:Splign:2.1.0"
     exon            63..1042
                     /gene="OR6C3"
                     /gene_synonym="OST709"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..1042
                     /gene="OR6C3"
                     /gene_synonym="OST709"
                     /note="isoform 1 is encoded by transcript variant 2;
                     olfactory receptor 6C3; HSA8"
                     /codon_start=1
                     /product="olfactory receptor 6C3 isoform 1"
                     /protein_id="NP_001375427.1"
                     /db_xref="CCDS:CCDS31819.1"
                     /db_xref="GeneID:254786"
                     /db_xref="HGNC:HGNC:15437"
                     /translation="MNHTMVTEFVLLGLSDDPDLQIVIFLFLFITYILSVTGNLTIIT
                     LTFVDSHLQTPMYFFLRNFSFLEISFTTVCIPRFLGAIITRNKTISYNNCAAQLFFFI
                     FMGVTEFYILTAMSYDRYVAICKPLHYTSIMNRKLCTLLVLCAWLSGFLTIFPPLMLL
                     LQLDYCASNVIDHFACDYFPLLQLSCSDTWLLEVIGFYFALVTLLFTLALVILSYMYI
                     IRTILRIPSASQRKKAFSTCSSHMIVISISYGSCIFMYANPSAKEKASLTKGIAILNT
                     SVAPMLNPFIYTLRNQQVKQAFKNVVHKVVFYANQ"
ORIGIN      
        1 agatgttcaa atggaagatg cactaagcta taatccaagt gagagagttg ctgagatcta
       61 agaacaaaaa ggagagtgga agaaggagag agagaaagga cgagacatga accacacaat
      121 ggtcacagag tttgtcctcc tgggcctttc tgatgatcct gaccttcaga ttgtgatttt
      181 tctcttttta tttatcacgt atatattaag tgttactgga aacctgacta tcatcaccct
      241 aacctttgtg gactcccatc tgcagacacc tatgtatttc ttcctccgga acttctcttt
      301 cttagaaatc tcatttacaa ccgtatgcat ccccagattt ctgggggcaa ttatcaccag
      361 gaataagact atttcctata acaactgtgc agcccaactc tttttcttta tcttcatggg
      421 ggtgactgaa ttttacattt taactgccat gtcctatgac cgctatgttg ccatctgcaa
      481 gccccttcat tacacatcca tcatgaacag gaaactctgc actctacttg tgctgtgtgc
      541 ctggctaagt gggtttctga ccattttccc accccttatg cttctcctcc agctggatta
      601 ctgtgcttcc aacgtcattg atcactttgc atgtgactat tttcccctct tacaactatc
      661 ttgttcagat acatggctcc tagaagtaat tggtttttac tttgctttgg ttactttgct
      721 gttcactttg gcattagtga ttttatctta catgtacatt atcaggacca ttttgagaat
      781 cccgtctgcc agtcaaagaa aaaaggcttt ctccacttgt tcttctcaca tgattgtcat
      841 ttccatttct tatggaagct gtatattcat gtatgctaat ccatctgcaa aagaaaaggc
      901 atcattgaca aaaggaatag ctattctcaa tacatctgtt gcccccatgc tgaacccctt
      961 catttacact ctgagaaacc agcaagtaaa acaagccttc aaaaatgtgg tccacaaagt
     1021 tgtgttttat gcaaatcaat ga
//
