LOCUS       NM_054105               2105 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 6 subfamily C member 2
            (OR6C2), mRNA.
ACCESSION   NM_054105 XM_002347332
VERSION     NM_054105.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2105)
  AUTHORS   Goodbourn,P.T., Bosten,J.M., Bargary,G., Hogg,R.E.,
            Lawrance-Owen,A.J. and Mollon,J.D.
  TITLE     Variants in the 1q21 risk region are associated with a visual
            endophenotype of autism and schizophrenia
  JOURNAL   Genes Brain Behav 13 (2), 144-151 (2014)
   PUBMED   24152035
REFERENCE   2  (bases 1 to 2105)
  AUTHORS   Scherer,S.E., Muzny,D.M., Buhay,C.J., Chen,R., Cree,A., Ding,Y.,
            Dugan-Rocha,S., Gill,R., Gunaratne,P., Harris,R.A., Hawes,A.C.,
            Hernandez,J., Hodgson,A.V., Hume,J., Jackson,A., Khan,Z.M.,
            Kovar-Smith,C., Lewis,L.R., Lozado,R.J., Metzker,M.L.,
            Milosavljevic,A., Miner,G.R., Montgomery,K.T., Morgan,M.B.,
            Nazareth,L.V., Scott,G., Sodergren,E., Song,X.Z., Steffen,D.,
            Lovering,R.C., Wheeler,D.A., Worley,K.C., Yuan,Y., Zhang,Z.,
            Adams,C.Q., Ansari-Lari,M.A., Ayele,M., Brown,M.J., Chen,G.,
            Chen,Z., Clerc-Blankenburg,K.P., Davis,C., Delgado,O., Dinh,H.H.,
            Draper,H., Gonzalez-Garay,M.L., Havlak,P., Jackson,L.R.,
            Jacob,L.S., Kelly,S.H., Li,L., Li,Z., Liu,J., Liu,W., Lu,J.,
            Maheshwari,M., Nguyen,B.V., Okwuonu,G.O., Pasternak,S., Perez,L.M.,
            Plopper,F.J., Santibanez,J., Shen,H., Tabor,P.E., Verduzco,D.,
            Waldron,L., Wang,Q., Williams,G.A., Zhang,J., Zhou,J., Allen,C.C.,
            Amin,A.G., Anyalebechi,V., Bailey,M., Barbaria,J.A., Bimage,K.E.,
            Bryant,N.P., Burch,P.E., Burkett,C.E., Burrell,K.L., Calderon,E.,
            Cardenas,V., Carter,K., Casias,K., Cavazos,I., Cavazos,S.R.,
            Ceasar,H., Chacko,J., Chan,S.N., Chavez,D., Christopoulos,C.,
            Chu,J., Cockrell,R., Cox,C.D., Dang,M., Dathorne,S.R., David,R.,
            Davis,C.M., Davy-Carroll,L., Deshazo,D.R., Donlin,J.E., D'Souza,L.,
            Eaves,K.A., Simons,R., Emery-Cohen,A.J., Escotto,M., Flagg,N.,
            Forbes,L.D., Gabisi,A.M., Garza,M., Hamilton,C., Henderson,N.,
            Hernandez,O., Hines,S., Hogues,M.E., Huang,M., Idlebird,D.G.,
            Johnson,R., Jolivet,A., Jones,S., Kagan,R., King,L.M., Leal,B.,
            Lebow,H., Lee,S., LeVan,J.M., Lewis,L.C., London,P.,
            Lorensuhewa,L.M., Loulseged,H., Lovett,D.A., Lucier,A.,
            Lucier,R.L., Ma,J., Madu,R.C., Mapua,P., Martindale,A.D.,
            Martinez,E., Massey,E., Mawhiney,S., Meador,M.G., Mendez,S.,
            Mercado,C., Mercado,I.C., Merritt,C.E., Miner,Z.L., Minja,E.,
            Mitchell,T., Mohabbat,F., Mohabbat,K., Montgomery,B., Moore,N.,
            Morris,S., Munidasa,M., Ngo,R.N., Nguyen,N.B., Nickerson,E.,
            Nwaokelemeh,O.O., Nwokenkwo,S., Obregon,M., Oguh,M., Oragunye,N.,
            Oviedo,R.J., Parish,B.J., Parker,D.N., Parrish,J., Parks,K.L.,
            Paul,H.A., Payton,B.A., Perez,A., Perrin,W., Pickens,A.,
            Primus,E.L., Pu,L.L., Puazo,M., Quiles,M.M., Quiroz,J.B.,
            Rabata,D., Reeves,K., Ruiz,S.J., Shao,H., Sisson,I., Sonaike,T.,
            Sorelle,R.P., Sutton,A.E., Svatek,A.F., Svetz,L.A., Tamerisa,K.S.,
            Taylor,T.R., Teague,B., Thomas,N., Thorn,R.D., Trejos,Z.Y.,
            Trevino,B.K., Ukegbu,O.N., Urban,J.B., Vasquez,L.I., Vera,V.A.,
            Villasana,D.M., Wang,L., Ward-Moore,S., Warren,J.T., Wei,X.,
            White,F., Williamson,A.L., Wleczyk,R., Wooden,H.S., Wooden,S.H.,
            Yen,J., Yoon,L., Yoon,V., Zorrilla,S.E., Nelson,D.,
            Kucherlapati,R., Weinstock,G. and Gibbs,R.A.
  CONSRTM   Baylor College of Medicine Human Genome Sequencing Center Sequence
            Production Team
  TITLE     The finished DNA sequence of human chromosome 12
  JOURNAL   Nature 440 (7082), 346-351 (2006)
   PUBMED   16541075
REFERENCE   3  (bases 1 to 2105)
  AUTHORS   Rouquier,S., Blancher,A. and Giorgi,D.
  TITLE     The olfactory receptor gene repertoire in primates and mouse:
            evidence for reduction of the functional fraction in primates
  JOURNAL   Proc Natl Acad Sci U S A 97 (6), 2870-2874 (2000)
   PUBMED   10706615
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122685.9.
            
            On Jul 31, 2020 this sequence version replaced NM_054105.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641202.1/ ENSP00000493222.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-84                AC122685.9         102494-102577       c
            85-2105             AC122685.9         93306-95326         c
FEATURES             Location/Qualifiers
     source          1..2105
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.2"
     gene            1..2105
                     /gene="OR6C2"
                     /gene_synonym="OR6C67"
                     /note="olfactory receptor family 6 subfamily C member 2"
                     /db_xref="GeneID:341416"
                     /db_xref="HGNC:HGNC:15436"
     exon            1..84
                     /gene="OR6C2"
                     /gene_synonym="OR6C67"
                     /inference="alignment:Splign:2.1.0"
     exon            85..2105
                     /gene="OR6C2"
                     /gene_synonym="OR6C67"
                     /inference="alignment:Splign:2.1.0"
     CDS             972..1910
                     /gene="OR6C2"
                     /gene_synonym="OR6C67"
                     /note="HSA3"
                     /codon_start=1
                     /product="olfactory receptor 6C2"
                     /protein_id="NP_473446.1"
                     /db_xref="CCDS:CCDS31824.1"
                     /db_xref="GeneID:341416"
                     /db_xref="HGNC:HGNC:15436"
                     /translation="MKNHTVIRTFILLGLTGDPHLQVLLFIFLFLTYMLSVTGNLTII
                     TLTLVDHHLKTPMYFFLRNFSFLEVSFTTVCIPRFLYNISMGDNTITYNACASQIFFV
                     ILFGATEFFLLAAMSYDRYVAICKPLHYVVIMNNRVCTLLVLCCWVAGLMIIVPPLSL
                     GLQLEFCDSNAIDHFSCDAGPLLKISCSDTWVIEQMVILMAVFALIITLVCVILSYLY
                     IVRTILKFPSVQQRKKAFSTCSSHMIVVSIAYGSCIFIYIKPSAKDEVAINKGVSVLT
                     TSVAPLLNPFIYTLRNKQVKQAFSDSIKRIAFLSKK"
ORIGIN      
        1 cttccttaac acaacacagt tcaacccatt agggagctgc cacctgaaat cgtgaaaaat
       61 tatcaaaaca gtaagtattt taagcctctg gtaaacatcc ttctactctc tatgtctatg
      121 agttcaactg atttgatttt cagatgtcac gaataagtga gaacatacga tgtctttcta
      181 aaggacctaa agatatattg aaaaagacgc agcctagaag actatattta gtggtgttaa
      241 atgtagattt gcttctggag cttgaaagga aaggaatcac aactgaacat caaatgaaag
      301 cctatgagaa tattcatttt gtaaaaacct tgaacacaac tttttctcac attatagata
      361 aaataattgt acatcaaccc atctacaggt actagagggt tgagaataag gaatgccagc
      421 agagaagaat aaaaagaccg gggaaaggct cagggacaac ggttgtattc tgttgtcatt
      481 gttgtttgtt tgtttttcag gaaaaatgta atttaatctt aatacaatcc tcagatgata
      541 acaactgaag agaattaatg ttattaatta cctggatata tcctatattc agagtttgtc
      601 ctggacaaaa aatgtttaag tacctataaa atgacatcat ttctttctaa cccatttgta
      661 aatccattcc atgtaacaaa ctacaatcaa ctgcatttgt aaattctgat ggataaggaa
      721 tgatcaaaga aaaagttgga ttgttttaca aaacttgatt tcttaaggag atatccactg
      781 ctcatatatg tgaaatttag aaaggttatt ggaacactgg caacattgat tattctataa
      841 agggagaaaa taaaagtagg ctggtcagct tggcttctag atgcatatcc ttttgctata
      901 gaattcaaat atctaccccc tcataaaccg tgatttttaa aggaggattg ggtagatatc
      961 aaagaacagt gatgaaaaac cacacagtaa taagaacttt tatcctgctg ggactgacag
     1021 gtgacccaca cctgcaagtt ctgcttttta tctttctatt tctcacctac atgttgagtg
     1081 taacagggaa cctgactatt atcaccctca cattggtgga ccaccacctt aaaactccta
     1141 tgtacttctt tctcagaaat ttttccttct tagaagtctc atttactaca gtctgcattc
     1201 ccagattctt gtacaatata tcaatggggg acaataccat tacctacaat gcttgtgcca
     1261 gtcaaatatt ctttgttatt ctctttggag caacagaatt ttttctcttg gcagccatgt
     1321 cctatgaccg ctatgtggcc atctgtaaac cccttcatta tgtggtcatc atgaacaaca
     1381 gggtgtgtac cttattagtt ctctgctgtt gggtggctgg cttgatgatc attgttccac
     1441 cacttagctt aggcctccag ctcgaattct gtgactccaa tgccattgat cattttagct
     1501 gtgatgcagg tcctctccta aagatctcat gctcagatac atgggtaata gaacagatgg
     1561 ttatacttat ggctgtattt gcactcatta tcaccctagt ttgtgtgatt ctgtcctact
     1621 tgtacatagt cagaacaatt ctgaagttcc cttctgttca gcaaaggaaa aaggcctttt
     1681 ctacctgttc atcccacatg attgtggttt ccattgccta tggaagctgc atcttcatct
     1741 atatcaagcc ctctgcaaaa gatgaggtgg ccataaataa aggagtttca gttcttacta
     1801 cttctgtcgc acccttgttg aaccccttca tttacacctt gaggaacaag caagtgaaac
     1861 aagctttcag tgactctata aagaggattg catttctctc aaagaagtag aagctgtgat
     1921 gaattggcat aaagtgaatg aagaaggctc cctaaatgtc atcctacagc ttttaactta
     1981 tttcattgct tcctgactac agtttagtca tgtgaacctt ctcaatgaca tttaatattg
     2041 catcctaatc ccatctttat caaaatcctt attatttcga accaaggtca tacattgtgt
     2101 tttcc
//
