LOCUS       NM_001005182            2055 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 6 subfamily C member 1
            (OR6C1), mRNA.
ACCESSION   NM_001005182 XM_372459
VERSION     NM_001005182.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2055)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2055)
  AUTHORS   Goodbourn,P.T., Bosten,J.M., Bargary,G., Hogg,R.E.,
            Lawrance-Owen,A.J. and Mollon,J.D.
  TITLE     Variants in the 1q21 risk region are associated with a visual
            endophenotype of autism and schizophrenia
  JOURNAL   Genes Brain Behav 13 (2), 144-151 (2014)
   PUBMED   24152035
REFERENCE   3  (bases 1 to 2055)
  AUTHORS   Shimada,M., Miyagawa,T., Kawashima,M., Tanaka,S., Honda,Y.,
            Honda,M. and Tokunaga,K.
  TITLE     An approach based on a genome-wide association study reveals
            candidate loci for narcolepsy
  JOURNAL   Hum Genet 128 (4), 433-441 (2010)
   PUBMED   20677014
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   4  (bases 1 to 2055)
  AUTHORS   Scherer,S.E., Muzny,D.M., Buhay,C.J., Chen,R., Cree,A., Ding,Y.,
            Dugan-Rocha,S., Gill,R., Gunaratne,P., Harris,R.A., Hawes,A.C.,
            Hernandez,J., Hodgson,A.V., Hume,J., Jackson,A., Khan,Z.M.,
            Kovar-Smith,C., Lewis,L.R., Lozado,R.J., Metzker,M.L.,
            Milosavljevic,A., Miner,G.R., Montgomery,K.T., Morgan,M.B.,
            Nazareth,L.V., Scott,G., Sodergren,E., Song,X.Z., Steffen,D.,
            Lovering,R.C., Wheeler,D.A., Worley,K.C., Yuan,Y., Zhang,Z.,
            Adams,C.Q., Ansari-Lari,M.A., Ayele,M., Brown,M.J., Chen,G.,
            Chen,Z., Clerc-Blankenburg,K.P., Davis,C., Delgado,O., Dinh,H.H.,
            Draper,H., Gonzalez-Garay,M.L., Havlak,P., Jackson,L.R.,
            Jacob,L.S., Kelly,S.H., Li,L., Li,Z., Liu,J., Liu,W., Lu,J.,
            Maheshwari,M., Nguyen,B.V., Okwuonu,G.O., Pasternak,S., Perez,L.M.,
            Plopper,F.J., Santibanez,J., Shen,H., Tabor,P.E., Verduzco,D.,
            Waldron,L., Wang,Q., Williams,G.A., Zhang,J., Zhou,J., Allen,C.C.,
            Amin,A.G., Anyalebechi,V., Bailey,M., Barbaria,J.A., Bimage,K.E.,
            Bryant,N.P., Burch,P.E., Burkett,C.E., Burrell,K.L., Calderon,E.,
            Cardenas,V., Carter,K., Casias,K., Cavazos,I., Cavazos,S.R.,
            Ceasar,H., Chacko,J., Chan,S.N., Chavez,D., Christopoulos,C.,
            Chu,J., Cockrell,R., Cox,C.D., Dang,M., Dathorne,S.R., David,R.,
            Davis,C.M., Davy-Carroll,L., Deshazo,D.R., Donlin,J.E., D'Souza,L.,
            Eaves,K.A., Simons,R., Emery-Cohen,A.J., Escotto,M., Flagg,N.,
            Forbes,L.D., Gabisi,A.M., Garza,M., Hamilton,C., Henderson,N.,
            Hernandez,O., Hines,S., Hogues,M.E., Huang,M., Idlebird,D.G.,
            Johnson,R., Jolivet,A., Jones,S., Kagan,R., King,L.M., Leal,B.,
            Lebow,H., Lee,S., LeVan,J.M., Lewis,L.C., London,P.,
            Lorensuhewa,L.M., Loulseged,H., Lovett,D.A., Lucier,A.,
            Lucier,R.L., Ma,J., Madu,R.C., Mapua,P., Martindale,A.D.,
            Martinez,E., Massey,E., Mawhiney,S., Meador,M.G., Mendez,S.,
            Mercado,C., Mercado,I.C., Merritt,C.E., Miner,Z.L., Minja,E.,
            Mitchell,T., Mohabbat,F., Mohabbat,K., Montgomery,B., Moore,N.,
            Morris,S., Munidasa,M., Ngo,R.N., Nguyen,N.B., Nickerson,E.,
            Nwaokelemeh,O.O., Nwokenkwo,S., Obregon,M., Oguh,M., Oragunye,N.,
            Oviedo,R.J., Parish,B.J., Parker,D.N., Parrish,J., Parks,K.L.,
            Paul,H.A., Payton,B.A., Perez,A., Perrin,W., Pickens,A.,
            Primus,E.L., Pu,L.L., Puazo,M., Quiles,M.M., Quiroz,J.B.,
            Rabata,D., Reeves,K., Ruiz,S.J., Shao,H., Sisson,I., Sonaike,T.,
            Sorelle,R.P., Sutton,A.E., Svatek,A.F., Svetz,L.A., Tamerisa,K.S.,
            Taylor,T.R., Teague,B., Thomas,N., Thorn,R.D., Trejos,Z.Y.,
            Trevino,B.K., Ukegbu,O.N., Urban,J.B., Vasquez,L.I., Vera,V.A.,
            Villasana,D.M., Wang,L., Ward-Moore,S., Warren,J.T., Wei,X.,
            White,F., Williamson,A.L., Wleczyk,R., Wooden,H.S., Wooden,S.H.,
            Yen,J., Yoon,L., Yoon,V., Zorrilla,S.E., Nelson,D.,
            Kucherlapati,R., Weinstock,G. and Gibbs,R.A.
  CONSRTM   Baylor College of Medicine Human Genome Sequencing Center Sequence
            Production Team
  TITLE     The finished DNA sequence of human chromosome 12
  JOURNAL   Nature 440 (7082), 346-351 (2006)
   PUBMED   16541075
REFERENCE   5  (bases 1 to 2055)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122684.3.
            
            On Jan 12, 2021 this sequence version replaced NM_001005182.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000642104.1/ ENSP00000492978.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-257               AC122684.3         23242-23498         c
            258-2055            AC122684.3         15477-17274         c
FEATURES             Location/Qualifiers
     source          1..2055
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.2"
     gene            1..2055
                     /gene="OR6C1"
                     /gene_synonym="OST267"
                     /note="olfactory receptor family 6 subfamily C member 1"
                     /db_xref="GeneID:390321"
                     /db_xref="HGNC:HGNC:8355"
     exon            1..257
                     /gene="OR6C1"
                     /gene_synonym="OST267"
                     /inference="alignment:Splign:2.1.0"
     exon            258..2055
                     /gene="OR6C1"
                     /gene_synonym="OST267"
                     /inference="alignment:Splign:2.1.0"
     CDS             291..1229
                     /gene="OR6C1"
                     /gene_synonym="OST267"
                     /codon_start=1
                     /product="olfactory receptor 6C1"
                     /protein_id="NP_001005182.1"
                     /db_xref="CCDS:CCDS31818.1"
                     /db_xref="GeneID:390321"
                     /db_xref="HGNC:HGNC:8355"
                     /translation="MRNHTEITEFILLGLTDDPNFQVVIFVFLLITYMLSITGNLTLI
                     TITLLDSHLQTPMYFFLRNFSILEISFTTVSIPKFLGNIISGDKTISFNNCIVQLFFF
                     ILLGVTEFYLLAAMSYDRYVAICKPLHCLSIMNRRVCTLLVFTSWLVSFLIIFPALML
                     LLKLHYCRSNIIDHFTCDYFPLLQLACSDTKFLEVMGFSCAAFTLMFTLALIFLSYIY
                     IIRTILRIPSTSQRTKAFSTCSSHMVVVSISYGSCIFMYIKPSAKDRVSLSKGVAILN
                     TSVAPMMNPFIYSLRNQQVKQAFINMARKTVFFTST"
ORIGIN      
        1 cagttctaaa acactttcag atactttccc tattttatat ttttgctcct ttctcactct
       61 ctactatcaa agacacatat tctgtctgga taaaatggga aaattaagac aaaagattga
      121 aaataggaag aaaatttctt caatgagaaa gtgaatgttt tcagaaatcc tggttttact
      181 ggatagcaat ggcatttgct aatatctcta ctattccagc cattctgaat gttagtgaaa
      241 ctatatgaaa atcagaggtc tggcagggga aaaaagaaag caactgaaga atgagaaacc
      301 atacagaaat aacagagttt attcttctgg gattaacaga tgacccaaat tttcaggttg
      361 taatctttgt cttcctgctc atcacctaca tgctcagcat cactgggaac ctgaccctta
      421 tcacaattac cctgctggat tcccacctgc agacccccat gtatttcttc ctcagaaatt
      481 tctccatatt agaaatttcg ttcacaaccg tcagtatacc caagtttctg ggtaacatta
      541 tttcaggaga taaaaccatt tcctttaata attgcatagt tcagttattt ttcttcattc
      601 tcttgggagt cacagagttt taccttctgg ctgccatgtc ctatgaccgc tatgtggcca
      661 tctgcaagcc tctgcattgc ttgagtatca tgaatcgaag agtctgcaca ctgcttgttt
      721 ttacttcttg gctggtttca ttcttaatca tattcccagc actcatgttg cttttaaagc
      781 ttcattactg taggtctaat attattgacc attttacctg tgattatttt ccactgctgc
      841 aacttgcttg ttcagacaca aaattcttag aggtgatggg attttcttgt gctgcgttta
      901 ctctaatgtt cactttggca ttaatatttc tgtcctacat atacattatc agaacaattt
      961 tgagaattcc ttctactagt cagaggacaa aggccttttc cacatgttct tcccacatgg
     1021 ttgttgtctc catctcttat ggcagctgca tttttatgta cattaaaccc tcagcaaaag
     1081 atagagtgtc cttgagcaag ggagtggcaa tactaaacac ctcagtagcc cccatgatga
     1141 acccctttat ttacagccta agaaatcagc aagtcaagca agctttcatt aacatggcaa
     1201 ggaagactgt atttttcaca agcacatgaa atggtatggt gtgatgaatt agaggcacag
     1261 gaaaggacaa tatgaatttt cagtagcttc ttcaatcaaa atggcctcct tgcagtcttc
     1321 tgcatcattt tcttttccct aaaagtttgc aagcatattt atttaatata tttctcattt
     1381 gacttaaaat aattttcttg tgtcttcctg acaccccctc ctttgaacaa ttttttgtaa
     1441 aattacaagc tcttcaagaa tattttgaaa actaaaatta ttcttcagtt tacttcaaga
     1501 aataaaatta tacctagata cattggaatg gctttataaa tatcaatatg atattctact
     1561 tgttatacac agaacatata gttttataat tttaatttat tcttatagaa attcccttca
     1621 ctatgctact gatgttctag gaaatatgtg aaagatacaa tataattttt aaaaaatgta
     1681 agtgaattca tttgaaaagc aaaaaaaaat ttcattactc attttaatta ggtatgttgg
     1741 tgaaattaat ctattaataa aggagcctag accattatca atatatactt ttttgttata
     1801 agtgctaagt agagctccat atttgtgaat cccataatat tctctctgta gaatgacaga
     1861 tgatggatag acacatatgc aaatacatac ataagttttg tcaaacatag agaatatata
     1921 gtatattcct aagatatgtt aattttctgt gagtggaaaa taagcttctt tctatcatta
     1981 cctaaaagta gtatgtaaat cttcttaaat tttagactag tttaaaacag gatatgtatc
     2041 caaattattt tatac
//
