LOCUS       NM_001005281            5153 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 6 subfamily B member 1
            (OR6B1), mRNA.
ACCESSION   NM_001005281 XM_069621 XM_374682
VERSION     NM_001005281.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5153)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 5153)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   3  (bases 1 to 5153)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC004853.1.
            
            On Aug 10, 2020 this sequence version replaced NM_001005281.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000641698.1/
                                                ENSP00000492907.1
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-331               AC004853.1         82249-82579
            332-5153            AC004853.1         85901-90722
FEATURES             Location/Qualifiers
     source          1..5153
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q35"
     gene            1..5153
                     /gene="OR6B1"
                     /gene_synonym="OR7-3; OR7-9"
                     /note="olfactory receptor family 6 subfamily B member 1"
                     /db_xref="GeneID:135946"
                     /db_xref="HGNC:HGNC:8354"
     exon            1..331
                     /gene="OR6B1"
                     /gene_synonym="OR7-3; OR7-9"
                     /inference="alignment:Splign:2.1.0"
     exon            332..5153
                     /gene="OR6B1"
                     /gene_synonym="OR7-3; OR7-9"
                     /inference="alignment:Splign:2.1.0"
     CDS             357..1292
                     /gene="OR6B1"
                     /gene_synonym="OR7-3; OR7-9"
                     /note="olfactory receptor OR7-9; olfactory receptor 7-3"
                     /codon_start=1
                     /product="olfactory receptor 6B1"
                     /protein_id="NP_001005281.1"
                     /db_xref="CCDS:CCDS43667.1"
                     /db_xref="GeneID:135946"
                     /db_xref="HGNC:HGNC:8354"
                     /translation="MELENQTRVTKFILVGFPGSLSMRAAMFLIFLVAYILTVAENVI
                     IILLVLQNRPLHKPMYFFLANLSFLETWYISVTVPKLLFSFWSVNNSISFTLCMIQLY
                     FFIALMCTECVLLAAMAYDRYVAICRPLHYPTIMSHGLCFRLALGSWAIGFGISLAKI
                     YFISCLSFCGPNVINHFFCDISPVLNLSCTDMSITELVDFILALVIFLFPLFITVLSY
                     GCILATILCMPTGKQKAFSTCASHLVVVTIFYSAIIFMYARPRVIHAFNMNKIISIFY
                     AIVTPSLNPFIYCLRNREVKEALKKLAYCQASRSD"
ORIGIN      
        1 aaaggtcttc acagctcagt gtgcctaaaa tcactgccat gttcaccagg aaggtgatgg
       61 gcaccctagt cccagggtgc tggacgaagc agcctcgtgc cacatcagat gcagatgtgg
      121 tcctagtgcc tagggctctc ctgtcatctt atcctggctt tcagcttgaa agcagtgggg
      181 caatctgtac ccagtcactc tttctaggtt tagaaagtgg gttcctcaca tctattcaat
      241 acctgaatct ttttcttctg catcttccta ttttagaatt ggtgaaggct ttgttttcac
      301 atttcatcct atcagaggct gctgtgccaa ggagagctaa gccctgtgtc tccaatatgg
      361 agttggagaa ccagacacga gtcaccaagt tcattctggt gggattccct gggagcttga
      421 gtatgcgggc agccatgttt ctgatattcc ttgtggccta tattctgaca gtggctgaaa
      481 acgtgatcat catcctattg gtgctgcaaa atcggccact gcacaagcct atgtacttct
      541 tcctggccaa cctgtccttc ttggagacct ggtacatctc tgtgactgtg cccaagttac
      601 tgtttagttt ttggtctgtg aacaacagca tctctttcac actctgtatg atacaactgt
      661 acttcttcat tgctctcatg tgcacagaat gtgtgcttct ggccgccatg gcctatgacc
      721 ggtatgtggc catctgtcgc ccactccact acccaaccat aatgagccat gggctctgct
      781 tccgcctcgc tcttggttcc tgggccattg gctttggcat ctccctggcg aagatctact
      841 tcatctcctg cctcagcttc tgtggtccca atgtcatcaa ccacttcttc tgtgacatct
      901 ctccagtact taatctctcc tgcacagaca tgtccataac tgagttggta gactttatcc
      961 tggcactggt catcttccta ttcccactct ttattactgt cctgtcctac ggatgcattc
     1021 tggccaccat attatgcatg cccacaggaa agcagaaagc gttctccact tgtgcctccc
     1081 atcttgtggt ggtcaccatt ttctattcag ccattatttt catgtatgct cgacctcgag
     1141 ttatccatgc cttcaacatg aacaaaatta tttccatctt ctatgccatt gtcactcctt
     1201 ctctcaaccc tttcatttat tgcctaagaa accgagaggt caaggaagct ctgaagaaac
     1261 tggcatattg ccaggccagc agatctgact agtcaattac agctgattag aaagaaaggt
     1321 ctgagtgggt gcctgtatgt cttcctccat cctttctcct ttaacgactc agttaggaca
     1381 ctgcccatgt taatatgaca tcaccatgtc tacttcaatc tcaggcgctt gggtatctgc
     1441 atctgtgcat atggtcagtg ctctaaggcc atacaccttc tagagagcta gagaaaacag
     1501 ttctcaatgg ttgtgacccc aaatggggtt tctaagactg tgagtaaatt tataactgag
     1561 ttaagtagga agagagatgg tgatgggtga gttagctgtt tttggatctg ccatacacta
     1621 atagctctgg ggccaacaaa ataggtggta gcttcctgat ttcccatctt tctaagacag
     1681 aggtagcaac tccctcaaca gtctcattct tgatgttctg ggagtgaatt ttggtggcag
     1741 agactgcttc ctgagttttt gcaacacttt ttgcaagcac ttactaacct gtattaaatc
     1801 cctttctgct taaactagtt agagtgcttt cttttatctg taagtgaatt gtaccttaca
     1861 caattgtgtt ttgtcttctg atataactca cacagttgcc ttttattgaa ttttatattt
     1921 cccttctagg tgccacaatg tatcctttag tggatgaaca taaaatagat gataaataaa
     1981 tatcatcaaa tatatgaatt gccaaacaat aattgccctc attacttctc ttttcttttg
     2041 atcttgatat cctcttgttc ccgccccgca ccccccttcc cgccctctct tttatcttct
     2101 cttggttttc cactttctcc acactcaact cagagataag taacaggttt caggaattga
     2161 cagagatttt cattccatgc catagtgatt ctcaactttc cttacctata tatctaacac
     2221 cctctacaca cacgctagaa cctcattgat caaatgtgct ttacacccat agaaggtaca
     2281 tagatatgct tgctcttggt tcatagtttt gccattggca aagggagata tatttttaag
     2341 ctgtattcaa catagtgggc caacatcagt gggaatttaa ttcttttatt gtaacagttt
     2401 taaacaggag agtttcttgc attaataaca tcttttagct aagaacaaac cacactttca
     2461 agaatgcttt ctctttcttc ttaattaaga aacgtgaggc agaattattt gttccatttt
     2521 ataaacttcc agaacagatg ttcaaggaag taaataacat acaaccacag acagtgggag
     2581 agcagaggtc aaagtcccag ttccctgaat ccaaaccctg ggtctttctc tagtgaatgg
     2641 gctctcccta gagagaaaac atacttcttt agaagccaag tatgaaagct agttgtaaag
     2701 gaatatagtt ggaattatga attactatac ctgcagaaca gtaataaaat aaaaatgaaa
     2761 acatgtgaat tataggtccc agaggaaaaa agaaacaaaa ataaaatgca agcacaactt
     2821 gctttaggga ataaatgtgc aaaagagaac aatgcttaaa atggaaagga tttaatgttt
     2881 gcttctggaa tgtagtttgg tcccttgatg caacaagtaa gttgtgatga atatatttct
     2941 atttaaaatc tagacacaca aaaaagagat tattttctga aaacttcaaa tgaatcaaaa
     3001 tataattgca tagtcatata gggatattaa atgtgtgcat taagaaagga aaagacatgt
     3061 tcagtaggga ttaggaaatg aaagataaaa aaactctggc aataacttga attttagccc
     3121 tggatatata ttcaccatgt gaccttggcc aaaccatcta tacttttgga aacactgagt
     3181 ctttatgtgt aaaacaggag taataatagt tgcttggtgt ttcttacgca atggttatga
     3241 ggatcaacta ccatgatgga aaagacattg attgttaaat atcttgggca gtgcatgatc
     3301 taagcaagct gccactagat tagggtttgc atgggaaaac tgtttgggaa ggctatgctc
     3361 tctggacctg tctaaaacaa ttccacacct agttgactcc acatactata gttatagtta
     3421 acctgggagg ctacaactat cagaggcagt ttatttcttt attatttctc atgaatatct
     3481 tggaaaggga gaatgtagaa gtagggtttc ttggggaatt ctattaaatt tttttttcaa
     3541 ataacagatg gaacattgag ctccttcccc tttgtggaag gaatacctaa gtgcacaggc
     3601 tcagcaaagt aaggacacag accaatgtag aaatctgcct caacagagaa aataatgtat
     3661 agtggattac tggttaaatt cacatagaaa caagctattt ctaaggtgac acacaaagca
     3721 agccggaagt ttcagggcat ttggtgatct tgttggggta accatcataa aaggctggta
     3781 gtcagtttca gtagtttatc cagagaacat gccctgaaga tttgattatc accatccaaa
     3841 ctcataagga accccacaaa ataaaatata aatatatatt aattacacat gcagtatata
     3901 ttttaaatca ctatatttat tcattcattt aactaatata tattaaagat ctattatgta
     3961 cgtgtaggga tacaatagca aaatattaaa acttgttacc tttgtgagca gaaacagata
     4021 gcagataata cctttgtgtg tgtgtgtgtg tgtgtgtata catatatata tctaacatac
     4081 atacatattg taatgggttg aatggtggct cccaaaaata tattttcaca ctttcaacct
     4141 ggaacttgtg attgggaact tatttgaaaa aaaaagagtc tttgaaatat aataaagtta
     4201 aggacctcaa actgagacca ttctggatta tccgagtgga ctcaatgtcc aatgacaagt
     4261 tccttatatg agagagaaga gaaaacagag aaggtgatgt gaaggtagag atagagattg
     4321 gagttctgca tccacaagcc aagaaatacc ttgggccacc agaagctgga agatataagt
     4381 aatgattctc cccccctaga gctgtcaaag gaagagagcc ctgatgacag cttgattttg
     4441 gactcctggc ctccagaact ataagacaat atatttctgt tgttttaagc taccaagttt
     4501 gtggtaattt gttataaaaa ccctgggaaa taaatacaca tcccaatttg ggtggcaata
     4561 agtgctatgg atggggagga agaaagcatg aaagtataat aggaagtgct gctggagatg
     4621 agaaatttta aataagatgg tcacagaatc accaagtgag gaagaaatgt ttgagcaaaa
     4681 acctggagaa gctgtgagag taagatatat ggctactttg gcaaagaaca ttccaggtag
     4741 agaaacagca agggaagata tggagtcttg tgtagtatgt ttgagggaca ttgaagagac
     4801 tgagcagcca gagcagtgag aaaagggtaa gcaggtgata tggtctggct ctgtttccct
     4861 acccaaatct catcttgatt gtaatcccca catatcaaaa ggggaacctg gtgggaagtg
     4921 attgcatcat gggggtggtt cccccatgct gttctcatga tagtgagtga gttctcacaa
     4981 gatccgatgg ttttaaaagt gtttggcagt tcccctccca ctttctctct ctctctcttg
     5041 ccgccatgtt agatgtgcct tccttcccct tcgcctcctg ccatgattgt aagtttcctg
     5101 aggcctcccc aaccatgtgg aactgtaagt caattaaacg tttttaaagt aaa
//
