LOCUS       NM_001004738            1110 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 5 subfamily L member 1
            (OR5L1), mRNA.
ACCESSION   NM_001004738 XM_166878
VERSION     NM_001004738.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1110)
  AUTHORS   Olender,T., Waszak,S.M., Viavant,M., Khen,M., Ben-Asher,E.,
            Reyes,A., Nativ,N., Wysocki,C.J., Ge,D. and Lancet,D.
  TITLE     Personal receptor repertoires: olfaction as a model
  JOURNAL   BMC Genomics 13, 414 (2012)
   PUBMED   22908908
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1110)
  AUTHORS   Menashe,I., Aloni,R. and Lancet,D.
  TITLE     A probabilistic classifier for olfactory receptor pseudogenes
  JOURNAL   BMC Bioinformatics 7, 393 (2006)
   PUBMED   16939646
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1110)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC136939.1 and AC036111.7.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Dec 20, 2016 this sequence version replaced NM_001004738.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jun 2015].
            
            Sequence Note: This gene is a segregating pseudogene. This RefSeq
            represents the protein encoded by the reference genome allele,
            which is predicted to be non-functional as an olfactory receptor
            according to the Classifier for Olfactory Receptor Pseudogenes.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC136939.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000625203.2/ ENSP00000485319.1
            polymorphic pseudogene :: PMID: 22908908
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-705               BC136939.1         1-705
            706-706             AC036111.7         109078-109078       c
            707-1110            BC136939.1         707-1110
FEATURES             Location/Qualifiers
     source          1..1110
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..1110
                     /gene="OR5L1"
                     /gene_synonym="OR11-151; OST262"
                     /note="olfactory receptor family 5 subfamily L member 1"
                     /db_xref="GeneID:219437"
                     /db_xref="HGNC:HGNC:8350"
     exon            1..1110
                     /gene="OR5L1"
                     /gene_synonym="OR11-151; OST262"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..1036
                     /gene="OR5L1"
                     /gene_synonym="OR11-151; OST262"
                     /note="olfactory receptor OR11-151"
                     /codon_start=1
                     /product="olfactory receptor 5L1"
                     /protein_id="NP_001004738.1"
                     /db_xref="GeneID:219437"
                     /db_xref="HGNC:HGNC:8350"
                     /translation="MGKENCTTVAEFILLGLSDVPELRVCLFLLFLLIYGVTLLANLG
                     MIALIQVSSRLHTPMYFFLSHLSSVDFCYSSIIVPKMLANIFNKDKAISFLGCMVQFY
                     LFCTCVVTEVFLLAVMAYDRFVAICNPLLYTVTMSWKVRVELASCCYFCGTVCSLIHL
                     CLALRIPFYRSNVINHFFCDLPPVLSLACSDITVNETLLFLVATLNESVTIMIILTSY
                     LLILTTILKMGSAEGRHKAFSTCASHLTAITVFHGTVLSIYCRPSSGNSGDADKVATV
                     FYTVVIPMLNSVIYSLRNKDVKEALRKVMGSKIHS"
ORIGIN      
        1 ggtgtctttt tacaggatac agccaaaact aaaatttaga ctatataatg gagaataatt
       61 tttaagtttc ttttcctcca atctcatata aattggagac atgggcaagg aaaactgcac
      121 cactgtggct gagttcattc tccttggact atcagatgtc cctgagttga gagtctgcct
      181 cttcctgctg ttccttctca tctatggagt cacgttgtta gccaacctgg gcatgattgc
      241 actgattcag gtcagctctc ggctccacac ccccatgtac tttttcctca gccacttgtc
      301 ctctgtagat ttctgctact cctcaataat tgtgccaaaa atgttggcta atatctttaa
      361 caaggacaaa gccatctcct tcctagggtg catggtgcaa ttctacttgt tttgcacttg
      421 tgtggtcact gaggtcttcc tgctggccgt gatggcctat gaccgctttg tggccatctg
      481 taaccctttg ctatacacag tcaccatgtc ttggaaggtg cgtgtggagc tggcttcttg
      541 ctgctacttc tgtgggacgg tgtgttctct gattcatttg tgcttagctc ttaggatccc
      601 cttctataga tctaatgtga ttaaccactt tttctgtgat ctacctcctg tcttaagtct
      661 tgcttgctct gatatcactg tgaatgagac actgctgttc ctggtggcca ctttgaatga
      721 gagtgttacc atcatgatca tcctcacctc ctacctgcta attctcacca ccatcctgaa
      781 gatgggctct gcagagggca ggcacaaagc cttctccacc tgtgcttccc acctcacagc
      841 tatcactgtc ttccatggaa cagtcctttc catttattgc aggcccagtt caggcaatag
      901 tggagatgct gacaaagtgg ccaccgtgtt ctacacagtc gtgattccta tgctgaactc
      961 tgtgatctac agcctgagaa ataaagatgt gaaagaagct ctcagaaaag tgatgggctc
     1021 caaaattcac tcctagggaa gattttatta gcacaattca ggattcccaa gtagtggcag
     1081 gcgggggttc acgggagagg cacagtgttg
//
