LOCUS       NM_001004736            3466 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 5 subfamily K member 1
            (OR5K1), mRNA.
ACCESSION   NM_001004736 XM_372997
VERSION     NM_001004736.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3466)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3466)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   3  (bases 1 to 3466)
  AUTHORS   Parmentier,M., Libert,F., Schurmans,S., Schiffmann,S., Lefort,A.,
            Eggerickx,D., Ledent,C., Mollereau,C., Gerard,C., Perret,J. et al.
  TITLE     Expression of members of the putative olfactory receptor gene
            family in mammalian germ cells
  JOURNAL   Nature 355 (6359), 453-455 (1992)
   PUBMED   1370859
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC074274.15.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Aug 6, 2020 this sequence version replaced NM_001004736.3.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000642057.1/ ENSP00000493267.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               AC074274.15        16351-16457         c
            108-3466            AC074274.15        6734-10092          c
FEATURES             Location/Qualifiers
     source          1..3466
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q11.2"
     gene            1..3466
                     /gene="OR5K1"
                     /gene_synonym="HSHTPCRX10; HTPCRX10; OR3-8"
                     /note="olfactory receptor family 5 subfamily K member 1"
                     /db_xref="GeneID:26339"
                     /db_xref="HGNC:HGNC:8349"
     exon            1..107
                     /gene="OR5K1"
                     /gene_synonym="HSHTPCRX10; HTPCRX10; OR3-8"
                     /inference="alignment:Splign:2.1.0"
     exon            108..3466
                     /gene="OR5K1"
                     /gene_synonym="HSHTPCRX10; HTPCRX10; OR3-8"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..1045
                     /gene="OR5K1"
                     /gene_synonym="HSHTPCRX10; HTPCRX10; OR3-8"
                     /note="olfactory receptor OR3-8"
                     /codon_start=1
                     /product="olfactory receptor 5K1"
                     /protein_id="NP_001004736.2"
                     /db_xref="CCDS:CCDS43115.1"
                     /db_xref="GeneID:26339"
                     /db_xref="HGNC:HGNC:8349"
                     /translation="MAEENHTMKNEFILTGFTDHPELKTLLFVVFFAIYLITVVGNIS
                     LVALIFTHRRLHTPMYIFLGNLALVDSCCACAITPKMLENFFSENKRISLYECAVQFY
                     FLCTVETADCFLLAAMAYDRYVAICNPLQYHIMMSKKLCIQMTTGAFIAGNLHSMIHV
                     GLVFRLVFCGSNHINHFYCDILPLYRLSCVDPYINELVLFIFSGSVQVFTIGSVLISY
                     LYILLTIFKMKSKEGRAKAFSTCASHFLSVSLFYGSLFFMYVRPNLLEEGDKDIPAAI
                     LFTIVVPLLNPFIYSLRNREVISVLRKILMKK"
ORIGIN      
        1 ttctcctaaa tgatcaagaa gatagagctt aattgtgaga tctactttaa aaactgttat
       61 caggcaacct actggcccct ttaaaactct taccagggaa aattcagaca agtcaggaat
      121 ggctgaagaa aatcatacca tgaaaaatga gtttatcctc acaggattta cagatcaccc
      181 tgagctgaag actctgctgt ttgtggtgtt ctttgccatc tatctgatca ccgtggtggg
      241 gaatattagt ttggtggcac tgatatttac acaccgtcgg cttcacacac caatgtacat
      301 ctttctggga aatctggctc ttgtggattc ttgctgtgcc tgtgctatta cccccaaaat
      361 gttagagaac ttcttttctg agaacaaaag gatttccctc tatgaatgtg cagtacagtt
      421 ttattttctt tgcactgtgg aaactgcaga ctgctttctt ctggcagcaa tggcctatga
      481 ccgctatgtg gccatatgca acccactgca gtaccacatc atgatgtcca agaaactctg
      541 cattcagatg accacagggg ccttcatagc tggaaacctg cattccatga ttcatgtagg
      601 gcttgtattt aggttagttt tctgtggatc gaatcacatc aaccactttt actgtgatat
      661 tcttcccttg tatagactct cttgtgttga tccttatatc aatgaactgg ttctattcat
      721 cttctcaggt tcagttcaag tctttaccat aggtagtgtc ttaatatctt atctctatat
      781 tcttcttact attttcaaaa tgaaatccaa agagggaagg gccaaagctt tttctacctg
      841 tgcatcccac tttttgtcag tttcattatt ctatggatct cttttcttca tgtacgttag
      901 accaaatttg cttgaagaag gggataaaga tataccagct gcaattttat ttacaatagt
      961 agttccctta ctaaatcctt tcatttatag cctgagaaat agggaagtaa taagtgtctt
     1021 aagaaaaatt ctgatgaaga aataatctca agaaagatgg aaacaagtga catctactat
     1081 agcttaatga tttaaatgca gcaaaaactt ccatgtgaaa ttacacaggg gaaatgcata
     1141 aattataagt aaaattttaa tatataagaa tacattcaaa ttaagtggca agaggtaagg
     1201 gtagaatata caaaaaagag taaactgtgg taaatcttaa ttcaaaataa caaaaatgaa
     1261 attctaattt tgaactcatt caagtaacaa tgtagtatgt tgtcaagctc ttggtctgtg
     1321 ttggcatcag ggatgataag catccaaaag aacacagcaa aactggaagt tacaagttca
     1381 aaggaccatt ccattaagca ttgataacca gataagttat tttaatagct tagagcatga
     1441 gcattatggt taaactgaaa gagtttaaga tcatatgatg gtcaaccagt aaaatcactt
     1501 acatccatga gcaacaaaat tgtgacaagc gaattttgag aaatcaattt taatagcatt
     1561 atggggacat tactgtagtt agaaaggaag tattaggaaa acgaaggtgt caaataatag
     1621 tgaatatcag atttccaaat ttaaattatt actgagttaa atattaaaca cagaatgtca
     1681 attttcaagt caagctacat taagagagtt ttatctactc ccatatctac ctgcataaat
     1741 ataccataac acaaacttcc agaaaagcag ttcaaacctc atgtaggatt tgaagagctt
     1801 ctttgttagt gagttaggtg caatgtctct gtgctcctac ttgagaggtg aggaaaggtt
     1861 tcaacaatag agaccactac cctgggtata ttatatatag aaatgtaaaa catagtgttg
     1921 ttaaactgta ggtagagttt atctaatttt tttttctttt cactattgca aaacctgaag
     1981 ttggtattgt gggtagagta atgatcttaa tgtgatatca ttttaaaaat tactttccaa
     2041 ttattcactc aacatatatt tattgaaatc ctgctatagg taggcattgt tctgggtgtt
     2101 gggccatatc agttacaaaa aatgccagtt tttccatctt ctcgaagaat agaatattgc
     2161 cacaattttt attactaact tctggattaa gaaggaccta tgtcacataa tagaaaaaca
     2221 tctcccttcc acctcttgct ctgaggacct gtctaaattc ccagaaagca attgtcaagt
     2281 gctccaggtt agccagccac cagaggctgg catcacagga aaaatcaata tgctgagtct
     2341 gtacagaaaa agtaatagga gagcagatga atttccaatt ccctaactca tcaatgcaaa
     2401 aatataacca cctagttttt ctttgtaacc tccaagaaaa tctaacctag ttcattccaa
     2461 ttatacttgg acatgtgaag atcttgtttg tttcaaatta aattccatca atttaggatt
     2521 tacccaacac tacctacatc cttccttcat cacatatagg tccttgcctg gtatcatggc
     2581 actgagcaca ggtgccagat tatatatgag ctctgtccaa gctatgattc tgtgagatgt
     2641 ttgagcctat ttgacccgtt ggttatttct tcatgccacc atcacttcag gtatctacgt
     2701 ccatgtctac tcctcaggct gcattgattt tcagctaaaa tgtctattta tccaacccac
     2761 aaggctttgg gttggctggc tctctctctc ttactcttca tctgctaatt tctgagtaaa
     2821 ttctcttgac ctcttcccag tgggtccagg aaatgttgaa atgcatcatt tttgcacttc
     2881 cgatgctaca caataccagt acaatgtagg attttgaaag cttacatggg tcccttttga
     2941 aggtcccttt tgcacatagg tcaccaaacc tccctgagca attgtcaccc cactcccatg
     3001 ccaggacacc ccctgggaat tgaaaccaca gaaccttttc caggcaacac gaactcttcc
     3061 cttcttgatg ttgctttttt tcccaactga ctgaatcctt aattctagga tgatacttag
     3121 ttttcacatc attacaaatg tttcccaaat gtacttttat ggagtaaaat tggactcaaa
     3181 aatgagactc tgtcttagtc tattctctct gtctggaata tcaaaggtat gctcagaaat
     3241 aaaaaaaaag tgagggataa cactgttgta tggctctggc ctccttttct tatatcaaaa
     3301 aatgtgaact gccctggtta ctgtctgaaa cggcaggcat agttattggg taagacagaa
     3361 ttacaggcag gctttatctg agaattactg gttatgggag aaaaatatct gataaaatga
     3421 atatttttaa aatctcgact cattttatgg tatgcagagg aaaaca
//
