LOCUS       NM_001005479            1113 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 5 subfamily H member 6
            (OR5H6), mRNA.
ACCESSION   NM_001005479
VERSION     NM_001005479.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1113)
  AUTHORS   Olender,T., Waszak,S.M., Viavant,M., Khen,M., Ben-Asher,E.,
            Reyes,A., Nativ,N., Wysocki,C.J., Ge,D. and Lancet,D.
  TITLE     Personal receptor repertoires: olfaction as a model
  JOURNAL   BMC Genomics 13, 414 (2012)
   PUBMED   22908908
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1113)
  AUTHORS   Menashe,I., Aloni,R. and Lancet,D.
  TITLE     A probabilistic classifier for olfactory receptor pseudogenes
  JOURNAL   BMC Bioinformatics 7, 393 (2006)
   PUBMED   16939646
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1113)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC137523.1.
            
            On Nov 9, 2018 this sequence version replaced NM_001005479.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jul 2015].
            
            Sequence Note: This gene is a segregating pseudogene. This RefSeq
            represents the protein encoded by the reference genome allele,
            which is predicted to be functional according to the Classifier for
            Olfactory Receptor Pseudogenes.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC137524.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000615035.3/
                                                ENSP00000480705.3
            polymorphic pseudogene           :: PMID: 22908908
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1113              BC137523.1         1-1113
FEATURES             Location/Qualifiers
     source          1..1113
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q11.2"
     gene            1..1113
                     /gene="OR5H6"
                     /gene_synonym="OR3-11"
                     /note="olfactory receptor family 5 subfamily H member 6"
                     /db_xref="GeneID:79295"
                     /db_xref="HGNC:HGNC:14767"
     exon            1..1113
                     /gene="OR5H6"
                     /gene_synonym="OR3-11"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..1019
                     /gene="OR5H6"
                     /gene_synonym="OR3-11"
                     /note="olfactory receptor OR3-11"
                     /codon_start=1
                     /product="olfactory receptor 5H6"
                     /protein_id="NP_001005479.2"
                     /db_xref="CCDS:CCDS33800.2"
                     /db_xref="GeneID:79295"
                     /db_xref="HGNC:HGNC:14767"
                     /translation="MEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLG
                     LIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFF
                     SLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHE
                     AFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISY
                     TIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESL
                     FYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV"
ORIGIN      
        1 caacacctct tccccaattt caactcacaa ttccattgca aatgttcctt tacctttgct
       61 tcatttttca gaggacatgc agtgaggaga tggaagagga aaatgcaaca ttgctgacag
      121 agtttgttct cacaggattt ttacatcaac ctgactgtaa aataccgctc ttcctggcat
      181 tcttggtaat atatctcatc accatcatgg ggaatcttgg tctaattgtt ctcatctgga
      241 aagaccctca ccttcatatc ccaatgtact tattccttgg gagtttagcc tttgtggatg
      301 cttcgttatc atccacagtg actccgaaga tgctgatcaa cttcttagct aagagtaaga
      361 tgatatctct ctctgaatgc atggtacaat ttttttccct tgtaaccact gtaaccacag
      421 aatgttttct cttggcaaca atggcatatg atcgctatgt agccatttgc aaagctttac
      481 tttatccagt cattatgacc aatgaactat gcattcagct attagtcttg tcatttatag
      541 gtggccttct tcatgcttta atccatgaag ctttttcatt cagattaacc ttctgtaatt
      601 ccaacataat acaacacttt tactgtgaca ttatcccatt gttaaagatt tcctgtactg
      661 attcctctat taactttcta atggttttta ttttcgcagg ttctgttcaa gtttttacca
      721 ttggaactat tcttatatct tatacaatta tcctctttac aatcttagaa aagaagtcta
      781 tcaaagggat acgaaaagct gtctccacct gtggggctca tctcttatct gtatctttat
      841 actatggccc cctcaccttc aaatatctgg gctctgcatc tccgcaagca gatgaccaag
      901 atatgatgga gtctctattt tacactgtca tagttccttt attaaatccc atgatctaca
      961 gcctgagaaa caagcaagta atagcttcat tcacaaaaat gttcaaaagc aatgtttaga
     1021 tctcatacaa tctctcttct ctatttacta aaattgtccc aagattgtgc aagttagagg
     1081 tgtctatgtc ttgccagcat tcaaagatga tgc
//
