LOCUS       NM_001001921            7860 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 5 subfamily AS member 1
            (OR5AS1), mRNA.
ACCESSION   NM_001001921 XM_166808
VERSION     NM_001001921.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7860)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 7860)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC068339.6.
            
            On Aug 21, 2020 this sequence version replaced NM_001001921.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000641320.1/
                                                ENSP00000493325.1
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-59                AC068339.6         107174-107232       c
            60-7860             AC068339.6         96695-104495        c
FEATURES             Location/Qualifiers
     source          1..7860
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..7860
                     /gene="OR5AS1"
                     /gene_synonym="OR11-168"
                     /note="olfactory receptor family 5 subfamily AS member 1"
                     /db_xref="GeneID:219447"
                     /db_xref="HGNC:HGNC:15261"
     exon            1..59
                     /gene="OR5AS1"
                     /gene_synonym="OR11-168"
                     /inference="alignment:Splign:2.1.0"
     exon            60..7860
                     /gene="OR5AS1"
                     /gene_synonym="OR11-168"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..1062
                     /gene="OR5AS1"
                     /gene_synonym="OR11-168"
                     /note="olfactory receptor OR11-168"
                     /codon_start=1
                     /product="olfactory receptor 5AS1"
                     /protein_id="NP_001001921.1"
                     /db_xref="CCDS:CCDS31516.1"
                     /db_xref="GeneID:219447"
                     /db_xref="HGNC:HGNC:15261"
                     /translation="MLESNYTMPTEFLFVGFTDYLPLRVTLFLVFLLVYTLTMVGNIL
                     LIILVNINSSLQIPMYYFLSNLSFLDISCSTAITPKMLANFLASRKSISPYGCALQMF
                     FFASFADAECLILAAMAYDRYAAICNPLLYTTLMSRRVCVCFIVLAYFSGSTTSLVHV
                     CLTFRLSFCGSNIVNHFFCDIPPLLALSCTDTQINQLLLFALCSFIQTSTFVVIFISY
                     FCILITVLSIKSSGGRSKTFSTCASHLIAVTLFYGALLFMYLQPTTSYSLDTDKVVAV
                     FYTVVFPMFNPIIYSFRNKDVKNALKKLLERIGYSNEWYLNRLRIVNI"
ORIGIN      
        1 tgttgatagc ccattgtgca aaataagtga taaaattcaa agttcttgat ggtgctgagg
       61 tccagtggga aaaacaagaa aactaagatg ttggagagta attacaccat gccaactgag
      121 ttcctatttg ttggattcac agattatcta cctctcagag tcacactgtt cttggtattc
      181 cttctggtat atacattaac tatggtcgga aatatactct taataattct agttaatatt
      241 aattcaagcc ttcaaattcc catgtattat tttcttagca acttatcttt cttagacatc
      301 agctgttcta cagcaatcac tcctaaaatg ctggcaaact tcttggcatc caggaaaagc
      361 atctctcctt atgggtgtgc actacaaatg tttttcttcg cttcttttgc tgatgctgag
      421 tgccttatcc tggcagcaat ggcttatgac cgctatgcag ccatctgcaa cccactgctc
      481 tatactacac tgatgtctag gagagtctgt gtctgcttca ttgtgttggc atatttcagt
      541 ggaagtacaa catcactggt ccatgtgtgc ctcacattca ggctgtcatt ttgtggctcc
      601 aatatcgtca atcatttttt ctgtgatatc ccacctcttc tggctttatc atgtacagac
      661 actcagatca accagcttct gctctttgct ttgtgcagct tcatccagac cagcactttt
      721 gtggtaatat ttatttctta cttctgcatc ctcatcactg tgttgagcat caagtcctca
      781 ggtggcagaa gcaaaacatt ctccacttgt gcttcccacc tcatagcagt caccttattc
      841 tatggagcgc tcctgtttat gtacttacag cccaccacta gctattccct agacactgat
      901 aaggtggtgg cagtgtttta tactgttgta tttcccatgt ttaatccaat aatttatagt
      961 ttcagaaaca aggatgtgaa aaatgctctc aaaaagctat tagaaagaat tggatattca
     1021 aatgaatggt atttaaatcg tttaagaata gtcaatatct aacttaccct tccaatctca
     1081 taaacagcaa ttatgccatg aacatcttat gtgttaacta ttttaaattt atcacatttt
     1141 cagaaataaa gataacttgt tatactcagt gcattaaaat gcttcatcct ctcttccaaa
     1201 aatgttctct ccacaattct actctataaa acattaccta attaaacata gtcattattt
     1261 atatccaatt agtgtttcta aaatgctttg tacattgatt ctgttcttta cgatgttgta
     1321 ttgaaggtaa atattgactt ttcagtcaat caatcggtat tagaagctac ttggcagcag
     1381 agcatgtgta tattggcttg ttttttccac cacctgtttg gcacctggta tactgcatgt
     1441 cttccttatc tgtgtgttta ggccatttat gcatagagtt ccattattgg aacactaagc
     1501 atcctactgc tcaaggtcat cgccaaggtc tgatttcaaa aattcaaaat attgtaacct
     1561 cagacataaa tttaagtatg gatggaggga tggatagatg gatagataga tgaatgactg
     1621 ggaaaataca gccttatttt atttggacag tgagtctata tttgtactca caaagcattt
     1681 gtcaatagag atattttata ataccaataa tctgttaggg atactgatgg tggtttcact
     1741 ggttctcaag aaattagaag acatgtagca atagtctcat tattattaag tcagaatgaa
     1801 gatacatcac attgtctttg ggctaagttg attactgcaa gaaattccct actttttcat
     1861 tcagagtggg taattgtgaa aaacaagttt gtgaatacta tcaagattat aaactgtaga
     1921 atttcctaat tatttatatt catgttgcta acatagtctt tgaggctcta tcttcaagaa
     1981 gaggtgaaaa ttacactgat cttttattct gtaaatttac aatgcaaggc aattaaagta
     2041 taaacaattt ttactctgta atcgattttg ataattaaat tatcagattt tttgtggttt
     2101 attctgatct ttcagtctga agtctctatt tactttttgt cttattttga caaagttaaa
     2161 gtgatacacc atgtacatgt gaaataaaaa agtgtgcatt ttgtaataat tatgaaaata
     2221 taaatggttg gattagttat attgaattta accttggaca tggagacaat aagatagcac
     2281 ctaatgaaat ggattgtttt gagtattaag taaagttata tatgtaaaat tactggtata
     2341 tgtatatgat ttgaaaatta aataatctaa tatttataga cataccatga agatactgtg
     2401 ggttctcttc tagatcacta caataaagca actgacgcag taaagtgtca cacaaatttt
     2461 tagatttctc agtgcatatc atagttatgt ttggtggctg gcaagatggt caaataggag
     2521 atgctccagt ctgctgctcc cagcaagatc aacagagaag gtgggtgatt tctgcatttc
     2581 caactgaggt acctggctca tctcattggg actggttaga cagtgggtgc agcccatggt
     2641 gggtgagcag aagcagggtg gggtgttgct tcacccggga agcacaaagg gttggcaaac
     2701 tccctccact agccaaggga agccatgaag gactgtgcca tgaggaacgg gtgcactctg
     2761 gcccagatac tatgcttttc ccatcgtctt cacaacacac ggaccaggag attcccttgg
     2821 gtgcctacat caccagctcc ctgggattga agcacaaaac tcggtggctg tttgggcagg
     2881 cactgagcta gctgcaggag ttttcttcat accccagtgg cacctggaat gccagcgaga
     2941 cagaaccatt cactcccctg gaaagggggc tgaagccagg gagccaagtg gtctagctca
     3001 gcagatccca cccccatgga gcccagcaag ctaagatcca ctggcttgaa attcttcctg
     3061 caagcatagc agtctgaagt tgacctggga tgctcgagct tggttggagg aggagagtcc
     3121 gccattgctg aggcttcagt aggcagtttt cccctcatag tgtaaacaaa gctgccagga
     3181 agtttgaact gggtggagcc caccgcagca ctgcaaaacc tctgtagcca gactgcctct
     3241 ctagattcct cctctctggg caggggatct ctaaaaaaaa ggcagcagcc ccagttaggg
     3301 gcctagagat aaaaccccca tccccctgag acagagcacc ttaaggaagg gatggctgtg
     3361 ggtgcagctt cagcagattt aaatgtccct gcctgctggc tctaaggaga gcagcatacc
     3421 tcccagcaca tcgttcaagc tctcctaaga gatagactcc tgcatcaagt gggtccttga
     3481 ccccgtgact cttgactggg agacaccttc cagtaggggt tgacagatac ctcataggag
     3541 agagctccag ctggcatctc acaggtgtgc ctctaggatg aagcttccaa aggaaggaac
     3601 gggcagcaat ctttactgtt ctgcagcctt cgcaggcaaa cagggtctgg agtggatctc
     3661 cagcaaactc cagcagacct gcagcagagg ggcctgacaa ttaaaaggaa aactaaggaa
     3721 tagcatcaat atcaacaaaa aggacgtcca ctcagaaact ccaccaccaa catcaaagac
     3781 caaaggtaga taaatgcatg atggtgagga aaaaccaatg caaaaaggct gaaaatttct
     3841 aaaaccagac atctcttctc ccacaaagga tcacaattcc acgccagcaa ggaaacaaaa
     3901 ctggacagag aatgagtttg atgaattgat ggaagtaatt gggtaataac aaatagaaga
     3961 attgggtaat atcaaactcc tctgagctaa aggagcatgt cctaactcaa tgcaaagaag
     4021 ctaagaacct cgaaaaatgg ttagaggaat tgctaattag aataactggt ttgaagagaa
     4081 cataaataac ctgatggagc tgaaaaacac agcacgagaa cttcatgaag catacacaag
     4141 catcaatagc caaatcgatc aaacagaagg aaggatatca gagattgaag atcaacttaa
     4201 tgaaataaag cttgaagaca agattagaga aaaaagaatg caaagaaatg aacaaagccc
     4261 ccagggatta tgggactatg tgaaaagagc aaacatatat ttgattggtg tacctgaaag
     4321 tgagggggag aatggaacca acttggaaaa cactcttcag gatatcatcc aggagaaact
     4381 ccccaaccta acaagacagg ccaacattca aattcaggaa atacatgtaa caccacaaag
     4441 atacacctca agaagagcaa cccccagaca cataatcatc agattcacca aggtggaaat
     4501 gaaggaaaaa atgttaaggt gttaaggaca gccagagaga aagctcacat tacccacaaa
     4561 gggaagccca tcagactaac agcggctgtc tcagcagaaa ccctataagc cagaagtgag
     4621 tgggggccaa tatccaacag tcttaaagaa aagaatttta aatgcagagt ttcatattca
     4681 gccaaactaa gcttcatgag tggagggaaa taaaatcctt tacagaaaag caaatgctga
     4741 gagattttgt caccaccagg cctgctttac aagagctcct gaaggaagca ctaaacatgg
     4801 aaaggtacaa ctggtaacag ccactgcaaa aaaaacaaat tttaaagaac attgacacta
     4861 cgaagaaacc acatcagcta atgggcaaaa taaccagcta gcatcataat gacaggatca
     4921 aattcacaca taacaatatt aaccttaaat gtaaatgggc tgaaagcccc agttaaaagc
     4981 cacagactgg caaattggat agagtcaaga ccgattggtg tgctgtattc aggagaccga
     5041 tctcatgtgc aaagcataca taggctcaaa ataacgggat ggaggaatat ttaccaagca
     5101 aatggatagc aaataaagaa aaaagaaaaa aaaaacaaca aagcacaggg gttgtaatcc
     5161 tagtctctga taaaacagac tataaccaaa aaagatcaaa agagataaag aaggcaatac
     5221 ataatggtaa aaggatcaat gcaacaagaa gagctaacta tactaaatat atatgtaccc
     5281 aatacaagag cacccaaatt cataaagcca gttcttagag atctatgaag agacttagac
     5341 taacacacaa aaatagtggg agactttaac accccacagt caacattaga cagaccaaga
     5401 cagaaaatta acaaggatat tcaggacttg aactcagctc tggaccaagc agacctaata
     5461 gacctctaca gaactctaca ccccaaatca atagaatata cattattctc agcaccacat
     5521 tgcatttatt ctaaaattga ccacaatatt gcaagtaaaa tactcctcag caaatgcaaa
     5581 acaatggaaa tcataacagt ctctcagacc acagtgcaat caaattagaa ctcaggatta
     5641 agaaactcac tcaaaaccac acatctacat ggaaactgaa caacctgctc atgaatgact
     5701 actgggtaaa taatgaaaat aaagcagaaa taaataagtt atttgaaacc aatgagaaca
     5761 aagacacaag gtatcagaat ctctgggaca tagctaaagc agtgtttaga ggaaaattca
     5821 cagtactaaa ggcccacaag agaaagcagg aaagatctaa aatcaacacc ctaacatcac
     5881 aattaaaaga actagataaa caagaacaaa caaattcaaa agcctcagaa gacaagaaat
     5941 aactaagatc agagcagaac tgaaggagat agagacatga aaaacccttc aaaaaatcaa
     6001 tgaatccagg agttggtttt tggaaaagat caacaaaata gaaagaacac tagccagact
     6061 aataaagaag aaaagagaga agaatcaaat agacacaata aaaaattata aaggggatat
     6121 caccactgtt cccacagaaa tacaaactac catcagagaa tactataaac acctccacac
     6181 aaataaacta gaaaacctgg aagaaatggt taaattcctg gaaacacaca ccctcccaag
     6241 tctaatccag gaagaagtca aatccatgaa tagaccaaaa acaagtccca aaattgaggc
     6301 agtaattaat agcctaccaa caaaaaatag tccaggacca gccaaattct accagacata
     6361 caaagaggag ctggtactat tccttctgaa actattccaa gcaatagaaa acgagaggct
     6421 cctccctaac tcattttatg cggccagcat catcctgata tgaaaacctg gcagagacac
     6481 agcaaaaaaa gaacatgcca ggccaatatc cctgatgaac atgatgcaaa aatcctcaaa
     6541 aaatactggc aaactgaatt cagcggcaca tcaaaaagct tatccaccaa tcaaattggc
     6601 tttatccctg ggatgcaagg ctggcttaac atacgcaaat caataaacgt aacccatctc
     6661 ataaacagaa ccaatgacaa aagcacatgt ttatctcaac agatgccgaa aaggcctttg
     6721 ataaaattca acacccttcg tgctaaaaac tctcaataaa ctaggtattg acaaacatat
     6781 ctccaaataa taagagctat tatgacaaac ccacagccaa tatcatactg aatgggcaaa
     6841 aactggacgc attccctttg aaaaccggca caaaacaatg atgccctctc tcaccactcc
     6901 tattcaacat agtattgaaa gtgctggcca gggcaatcag gcaagataaa gaaataaagg
     6961 atattcaaat aggaaaagag gaagtcaaat cgtctctgtt tgcagatgac atgattgtat
     7021 atttagaaaa ccccatcgtc tcaggccaaa atctccttaa gctgataagc aacttcagca
     7081 aaatgtcagg atacaaaatc aatgtgcaaa aatcacaagc attcctatac accaataaca
     7141 gacaaacaga gccaaatcga atgaactgcc attcacaatt gctacaaaag agtgtaaaat
     7201 acctagaaat acaacttacg agggatatga atgacctctt caaggagaac tacaaattag
     7261 tgctcaagga aataagagag gacacaaaca aatggaaaaa cattccatgc tcatggatat
     7321 gaagaatcaa tatcatgaaa atggccatct actgccctaa gtaattttta gattcaatac
     7381 tatccccgtc aagctatcat tgaatttctt cacagaatta gaaaaaaaaa aaaactactt
     7441 taaatttcat gtggaaccag aaaacagccc atgtagccca ggcaatccta agcaaaaaga
     7501 acaaagctgg aggcatcatg ctacctggct tcaaactata ctacaaggct acagtaataa
     7561 aaacagtatg gtcctggtac caaagcagat atatagacca atggaacaga atagaggcct
     7621 cacaaataac accacacatc tacaaccatc tgatctttga caaacctgac aaaaacaagc
     7681 aatgaggaaa ggattcccta tttaataaat ggtgttggga aaactggcta gccatatgca
     7741 gaaagcagaa actggacccc ttccttatat cttatacaaa aattaactca agatggatta
     7801 aagacttaaa cataaaacca tcaacacgct gaaccatgca cttgccttgc tattgatggc
//
