LOCUS       NM_001004730             933 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 5 subfamily AR member 1
            (OR5AR1), mRNA.
ACCESSION   NM_001004730 XM_166845
VERSION     NM_001004730.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 933)
  AUTHORS   Olender,T., Waszak,S.M., Viavant,M., Khen,M., Ben-Asher,E.,
            Reyes,A., Nativ,N., Wysocki,C.J., Ge,D. and Lancet,D.
  TITLE     Personal receptor repertoires: olfaction as a model
  JOURNAL   BMC Genomics 13, 414 (2012)
   PUBMED   22908908
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 933)
  AUTHORS   Yang,Q., Kathiresan,S., Lin,J.P., Tofler,G.H. and O'Donnell,C.J.
  TITLE     Genome-wide association and linkage analyses of hemostatic factors
            and hematological phenotypes in the Framingham Heart Study
  JOURNAL   BMC Med Genet 8 Suppl 1 (Suppl 1), S12 (2007)
   PUBMED   17903294
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 933)
  AUTHORS   Menashe,I., Aloni,R. and Lancet,D.
  TITLE     A probabilistic classifier for olfactory receptor pseudogenes
  JOURNAL   BMC Bioinformatics 7, 393 (2006)
   PUBMED   16939646
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 933)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB065740.1.
            
            On Sep 19, 2004 this sequence version replaced XM_166845.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jun 2015].
            
            Sequence Note: This gene is a segregating pseudogene. This RefSeq
            represents the protein encoded by the reference genome allele,
            which is predicted to be non-functional as an olfactory receptor
            according to the Classifier for Olfactory Receptor Pseudogenes.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC140745.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000624596.2/ ENSP00000485240.1
            polymorphic pseudogene :: PMID: 22908908
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..933
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..933
                     /gene="OR5AR1"
                     /gene_synonym="OR11-209"
                     /note="olfactory receptor family 5 subfamily AR member 1"
                     /db_xref="GeneID:219493"
                     /db_xref="HGNC:HGNC:15260"
     CDS             1..933
                     /gene="OR5AR1"
                     /gene_synonym="OR11-209"
                     /note="olfactory receptor OR11-209"
                     /codon_start=1
                     /product="olfactory receptor 5AR1"
                     /protein_id="NP_001004730.1"
                     /db_xref="GeneID:219493"
                     /db_xref="HGNC:HGNC:15260"
                     /translation="MDKENSSMVTEFIFMGITQDPQMEIIFFVVFLIVYLVNVVGNIG
                     MIILITTDTQLHTPMYFFLCNLSFVDLGYSSAIAPRMLADFLTNHKVISFSSCATQFA
                     FFVGFVDAECYVLAAMAYGRFVAICRPLHYSTFMSKQVCLALMLGSYLAGLVSLVAHT
                     TLTFSLSYCGSNIINHFFCEIPPLLALSCSDTYISEILLFSLCGFIEFSTILIIFISY
                     TFILVAIIRMRSAEGRLKAFSTCGSHLTGITLFYGTVMFMYLRPTSSYSLDQDKWASV
                     FYTVIIPMLNPLIYSLRNKDVKAAFKKLIGKKSQ"
     exon            1..933
                     /gene="OR5AR1"
                     /gene_synonym="OR11-209"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggataaag aaaacagctc aatggtgact gagtttatct tcatgggcat cacccaggac
       61 cctcagatgg agatcatctt cttcgtggtc ttcctcatag tttacctggt taatgtagtg
      121 gggaatattg gtatgattat cctgattaca acagacactc agcttcacac acccatgtat
      181 tttttcctct gcaacctctc ctttgttgac ctgggctact cctcagccat tgcccccagg
      241 atgctggctg acttcctaac aaatcacaaa gttatctcct tctccagctg tgccacccag
      301 tttgcttttt ttgtaggttt tgtggatgct gagtgctatg tcctggcagc catggcctat
      361 ggtcgttttg tggccatttg tcgacccctc cactatagca ccttcatgtc caagcaggtc
      421 tgcttggctc tcatgctggg ctcttacctg gctggtctag tgagtttagt agcccacact
      481 accctcacct tcagcctgag ttactgtggt tccaatatca tcaatcattt cttctgcgaa
      541 atcccaccac tcttggccct ctcttgctca gacacctaca tcagtgagat cttgctcttc
      601 agtctgtgtg gcttcattga attcagcacc atcctcatca tcttcatctc ctataccttt
      661 atccttgttg caatcatcag aatgcgttca gctgaaggcc gccttaaggc tttctccacc
      721 tgcgggtctc accttactgg catcaccctc ttctatggca cagtcatgtt tatgtacctg
      781 aggccaacat ccagctactc cctggaccaa gacaagtggg cctctgtgtt ctacacggtt
      841 atcatcccca tgttaaatcc cttgatctac agtttgcgga acaaggatgt gaaagctgct
      901 ttcaaaaagc taattggaaa aaaatctcaa taa
//
