LOCUS       NM_054106                930 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 5 subfamily AC member 2
            (OR5AC2), mRNA.
ACCESSION   NM_054106
VERSION     NM_054106.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Muzny,D.M., Scherer,S.E., Kaul,R., Wang,J., Yu,J., Sudbrak,R.,
            Buhay,C.J., Chen,R., Cree,A., Ding,Y., Dugan-Rocha,S., Gill,R.,
            Gunaratne,P., Harris,R.A., Hawes,A.C., Hernandez,J., Hodgson,A.V.,
            Hume,J., Jackson,A., Khan,Z.M., Kovar-Smith,C., Lewis,L.R.,
            Lozado,R.J., Metzker,M.L., Milosavljevic,A., Miner,G.R.,
            Morgan,M.B., Nazareth,L.V., Scott,G., Sodergren,E., Song,X.Z.,
            Steffen,D., Wei,S., Wheeler,D.A., Wright,M.W., Worley,K.C.,
            Yuan,Y., Zhang,Z., Adams,C.Q., Ansari-Lari,M.A., Ayele,M.,
            Brown,M.J., Chen,G., Chen,Z., Clendenning,J.,
            Clerc-Blankenburg,K.P., Chen,R., Chen,Z., Davis,C., Delgado,O.,
            Dinh,H.H., Dong,W., Draper,H., Ernst,S., Fu,G.,
            Gonzalez-Garay,M.L., Garcia,D.K., Gillett,W., Gu,J., Hao,B.,
            Haugen,E., Havlak,P., He,X., Hennig,S., Hu,S., Huang,W.,
            Jackson,L.R., Jacob,L.S., Kelly,S.H., Kube,M., Levy,R., Li,Z.,
            Liu,B., Liu,J., Liu,W., Lu,J., Maheshwari,M., Nguyen,B.V.,
            Okwuonu,G.O., Palmeiri,A., Pasternak,S., Perez,L.M., Phelps,K.A.,
            Plopper,F.J., Qiang,B., Raymond,C., Rodriguez,R.,
            Saenphimmachak,C., Santibanez,J., Shen,H., Shen,Y., Subramanian,S.,
            Tabor,P.E., Verduzco,D., Waldron,L., Wang,J., Wang,J., Wang,Q.,
            Williams,G.A., Wong,G.K., Yao,Z., Zhang,J., Zhang,X., Zhao,G.,
            Zhou,J., Zhou,Y., Nelson,D., Lehrach,H., Reinhardt,R., Naylor,S.L.,
            Yang,H., Olson,M., Weinstock,G. and Gibbs,R.A.
  TITLE     The DNA sequence, annotation and analysis of human chromosome 3
  JOURNAL   Nature 440 (7088), 1194-1198 (2006)
   PUBMED   16641997
REFERENCE   2  (bases 1 to 930)
  AUTHORS   Rouquier,S., Blancher,A. and Giorgi,D.
  TITLE     The olfactory receptor gene repertoire in primates and mouse:
            evidence for reduction of the functional fraction in primates
  JOURNAL   Proc Natl Acad Sci U S A 97 (6), 2870-2874 (2000)
   PUBMED   10706615
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC133439.2.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000358642.2/ ENSP00000351466.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-930               AC133439.2         2510-3439
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q11.2"
     gene            1..930
                     /gene="OR5AC2"
                     /gene_synonym="HSA1"
                     /note="olfactory receptor family 5 subfamily AC member 2"
                     /db_xref="GeneID:81050"
                     /db_xref="HGNC:HGNC:15431"
     CDS             1..930
                     /gene="OR5AC2"
                     /gene_synonym="HSA1"
                     /codon_start=1
                     /product="olfactory receptor 5AC2"
                     /protein_id="NP_473447.1"
                     /db_xref="CCDS:CCDS33796.1"
                     /db_xref="GeneID:81050"
                     /db_xref="HGNC:HGNC:15431"
                     /translation="MDISEGNKTLVTEFVLTGLTDRPWLHVLFFVVFLVVYLITMVGN
                     LGLIVLIWNDPHLHMPMYLFLGGLAFSDACTSTSITPRMLVNFLDKTAMISLAECITQ
                     FYFFASSATTECFLLVMMAYDRYVAICNPLLYPVMMSNKLSAQLLSISYVIGFLHPLV
                     HVSLLLRLTFCRFNIIHYFYCEILQLFKISCNGPSINALMIFIFGAFIQIPTLMTIII
                     SYTRVLFDILKKKSEKGRSKAFSTCGAHLLSVSLYYGTLIFMYVRPASGLAEDQDKVY
                     SLFYTIIIPLLNPFIYSLRNKKVMHALRRVIRK"
     exon            1..930
                     /gene="OR5AC2"
                     /gene_synonym="HSA1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggatatat cagagggaaa taagactctt gtgacagagt ttgttctcac aggacttaca
       61 gatcgaccat ggctgcacgt cctcttcttt gttgtgtttt tggtggtcta tctcatcacc
      121 atggtgggca accttggact gatagttcta atttggaacg acccccatct tcatatgccc
      181 atgtacttat tccttggtgg tttagccttt tcagatgctt gtacttcaac ctctataacc
      241 cctaggatgc tggtcaattt cttagacaag actgcaatga tatccctagc tgagtgcatc
      301 acccagtttt acttttttgc ttccagtgca actacagaat gcttcctcct ggtgatgatg
      361 gcctatgacc gctatgtagc catatgtaat cccttgcttt atccagtgat gatgtccaac
      421 aaactcagcg ctcagttgct aagtatttca tatgtaattg gtttcctgca tcctctggtt
      481 catgtgagtt tactattgcg actaactttc tgcaggttta acataataca ttatttctac
      541 tgtgaaattt tacaactgtt caaaatttca tgcaatggtc catctattaa cgcactaatg
      601 atatttattt ttggtgcttt tatacaaata cccactttaa tgactatcat aatctcttat
      661 actcgtgtgc tctttgatat tctgaaaaaa aagtctgaaa agggcagaag caaagccttc
      721 tccacatgcg gcgcccatct gctttctgtc tcattgtact acggaactct gatcttcatg
      781 tatgtgcgtc ctgcatctgg cttagctgaa gaccaagaca aagtgtattc tctgttttac
      841 acgattataa ttcccctgct aaacccattt atttacagct tgagaaataa aaaagtcatg
      901 catgcattga gaagagttat aaggaagtaa
//
