LOCUS       NM_001004728            8612 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 5 subfamily A member 1
            (OR5A1), mRNA.
ACCESSION   NM_001004728 XM_166899
VERSION     NM_001004728.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8612)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 8612)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP003778.3.
            
            On Jul 27, 2020 this sequence version replaced NM_001004728.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641045.1/ ENSP00000493195.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-367               AP003778.3         58593-58959
            368-8612            AP003778.3         65260-73504
FEATURES             Location/Qualifiers
     source          1..8612
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..8612
                     /gene="OR5A1"
                     /gene_synonym="OR11-249; OR5A1P; OST181"
                     /note="olfactory receptor family 5 subfamily A member 1"
                     /db_xref="GeneID:219982"
                     /db_xref="HGNC:HGNC:8319"
     exon            1..367
                     /gene="OR5A1"
                     /gene_synonym="OR11-249; OR5A1P; OST181"
                     /inference="alignment:Splign:2.1.0"
     exon            368..8612
                     /gene="OR5A1"
                     /gene_synonym="OR11-249; OR5A1P; OST181"
                     /inference="alignment:Splign:2.1.0"
     CDS             401..1348
                     /gene="OR5A1"
                     /gene_synonym="OR11-249; OR5A1P; OST181"
                     /note="olfactory receptor, family 5, subfamily A, member 1
                     pseudogene; olfactory receptor OR11-249"
                     /codon_start=1
                     /product="olfactory receptor 5A1"
                     /protein_id="NP_001004728.1"
                     /db_xref="CCDS:CCDS31561.1"
                     /db_xref="GeneID:219982"
                     /db_xref="HGNC:HGNC:8319"
                     /translation="MSITKAWNSSSVTMFILLGFTDHPELQALLFVTFLGIYLTTLAW
                     NLALIFLIRGDTHLHTPMYFFLSNLSFIDICYSSAVAPNMLTDFFWEQKTISFVGCAA
                     QFFFFVGMGLSECLLLTAMAYDRYAAISSPLLYPTIMTQGLCTRMVVGAYVGGFLSSL
                     IQASSIFRLHFCGPNIINHFFCDLPPVLALSCSDTFLSQVVNFLVVVTVGGTSFLQLL
                     ISYGYIVSAVLKIPSAEGRWKACNTCASHLMVVTLLFGTALFVYLRPSSSYLLGRDKV
                     VSVFYSLVIPMLNPLIYSLRNKEIKDALWKVLERKKVFS"
ORIGIN      
        1 atgaaacatc tccaaggaca gaagaaaaaa acctctcccc aatttacccc caaccccagc
       61 tttgaacatt ttctcaaaat gaccctaaat gcagatatta gctgatgcca gaagagcttc
      121 ttaaagatta caacctccat cctttcttta tatatctttt tcttccttta ctctgcccca
      181 aagcacacct tctatgcacc aagaggatat tttgatcctt gatgaaaaaa ccagccgcaa
      241 gctctctcca aactcattag cactttggta attggaagca gccactgaaa cccaattaaa
      301 ctccttccaa agcagaacaa ctcaaaacag gtatcagcta aagggcagac agagcaggag
      361 caacagggtc tgcatcttgt ccttgtggtc cacgggaagc atgtccataa ccaaagcctg
      421 gaacagctca tcagtgacca tgttcatcct cctgggattc acagaccatc cagaactcca
      481 ggccctcctc tttgtgacct tcctgggcat ctatcttacc accctggcct ggaacctggc
      541 cctcattttt ctgatcagag gtgacaccca tctgcacaca cccatgtact tcttcctaag
      601 caacttatct ttcattgaca tctgctactc ttctgctgtg gctcccaata tgctcactga
      661 cttcttctgg gagcagaaga ccatatcatt tgtgggctgt gctgctcagt tttttttctt
      721 tgtcggcatg ggtctgtctg agtgcctcct cctgactgct atggcatacg accgatatgc
      781 agccatctcc agcccccttc tctaccccac tatcatgacc cagggcctct gtacacgcat
      841 ggtggttggg gcatatgttg gtggcttcct gagctccctg atccaggcca gctccatatt
      901 taggcttcac ttttgcggac ccaacatcat caaccacttc ttctgcgacc tcccaccagt
      961 cctggctctg tcttgctctg acaccttcct cagtcaagtg gtgaatttcc tcgtggtggt
     1021 cactgtcgga ggaacatcgt tcctccaact ccttatctcc tatggttaca tagtgtctgc
     1081 ggtcctgaag atcccttcag cagagggccg atggaaagcc tgcaacacgt gtgcctcgca
     1141 tctgatggtg gtgactctgc tgtttgggac agcccttttc gtgtacttgc gacccagctc
     1201 cagctacttg ctaggcaggg acaaggtggt gtctgttttc tattcattgg tgatccccat
     1261 gctgaaccct ctcatttaca gtttgaggaa caaagagatc aaggatgccc tgtggaaggt
     1321 gttggaaagg aagaaagtgt tttcttaggt catgcgtaga aacttattta tccaaactgc
     1381 tggagaatta aacaatccaa gccttcacct ccacctctgc ctcaggcaag ggagatattt
     1441 ggtgctctca tttgtggaga ctcttccctc cagattcctc tcacccttcc tcatggtcac
     1501 ttgtctactg actgtgccat agatagccaa aaagggaagg aatttcttca gaaaaaaaaa
     1561 aaaaaaaaaa agaacctccc caggataacc tattttcaca ataatcacaa taactagcct
     1621 ttattgggcc cttagtatgt accaggcaca aaagttattt aattaaatac tcattgcagt
     1681 actaaaatac acaatgaact atctgtatgt tacaaaataa ggaaacagtg tgtcagcaag
     1741 gaaaattaac ttgctcaggg tcaccaagga agaggcagaa ctctcattca caccaaggtc
     1801 ttcctgactc cagagcccac gttctgccca aacgctgcac tccacattca acaaaaaaat
     1861 agcccaaaag tagtacgagt atataactct tgttactggc atatggcaga atctgaaaag
     1921 atacactatg tgtagttaag gtaaattaga aaaacaagat gcctacctca tcaaatgccc
     1981 tctctaggat ctccctgttg aattccaatt atggctactg agtaatttgc taagcaaatg
     2041 ctgaaggaca ttccccttgg ctgccatttc tctctttctc agctatgtaa gggctgggaa
     2101 atttgagtcc aatggtgtca taccaatact cttcttttct cagtctcagt cccctaaact
     2161 gcctatcagt cagtacctcc ttgatttttc tttaatattt cactaaatgt tgtatttttt
     2221 ttcttttaat ttaatttaat tttattttat tttaagttcc gggatacata tgcaggatgt
     2281 gcaggtttgt tacataggta aacatatgtc atggtgattt gctgcaccta tccacccatc
     2341 acctaggtat taagccccac atccgttagc tatttatccc gatgctctcc ctcctccctg
     2401 cctcctgaca ggccccaatg tgcattgttc ccctctctgt gtccatgtgt tctcattgtt
     2461 tagctcttac ttacaagtga gaacattgga tatttggtta tctgttcttg ggttagtttg
     2521 ctgaggataa tggcttccag ctctatccat gtccctgcaa agaacactaa ttccttcctt
     2581 ttatggctgc atagtattcc atggtatgta tgtaccatat tttctttatc cagtctctca
     2641 ttgatgggaa tttgggttga ttccatgtct ttgctattgt gaatagtgct gcaatgaaca
     2701 tacacatgca tgtatattta taatagaatt atttatattc ctttggatat atacccagta
     2761 ataagattgc tgggtcaaat gatatttcca tttctaggtc tttgaggact cgccacactg
     2821 tcttccacaa tggttgaact aatttacatt cccaccaaca gtataaaagt gttcctattt
     2881 ctccacagcc tcgccagcat ctgttgtttc ttgacttttt aataattgcc attctgacta
     2941 gcatgagatg gtatctcatt gtgatttttt atttgcattt ctctaataat tagtgatgtt
     3001 gagctttttt tcatatgttt gttggccata caaatgtctt cttttgagaa gtgtctgttc
     3061 atgtcatttg cccactttta gatagggttg tttgtttttt tcttgtaaat ttgtttaagt
     3121 tacctttgtc agatagatag attgcaaaaa ttttctccca ttctgtaggt tgtctgttca
     3181 ttctaatgat agcttctttt gcagaatctc tttagtttaa ttagatccca tttgccaatg
     3241 tttgcttttg ttgcaattgc ttttgacgtt ttcatcatga aatctttgcc agtgcctatg
     3301 tcctaaatgg cattgcctag attttcttct aggattttta tagtttgggg ctttacattt
     3361 aaatctttaa tccatcttga gttaattttt gtataaagtt taaggaactg gtccattttc
     3421 aattttctgt atatggctag ccagttttcc cagcaccatt tattagatag ggaatccttt
     3481 ccccattgct tgtctttatc aggtttgtca aagattcaat ggttgtagat gtgcagtctt
     3541 atttctgaga tctctattgt gttctattgg tctacgtgtc tgtttttgta caagtaccat
     3601 gttgttttgg ttaccataga cttgtagtat agtttgaagt cagggagtgt aatgcctccg
     3661 gctttgttct ttttgcttag gattgtcttg actatactag ctccttgatt ttaaccatgc
     3721 cattccttta ccagttcagg acctgcctcc atttcacagt ttggtgtcct ttttgatcac
     3781 cacaccctga attccccttg ctatcttcta tctgaaccca ttgctcctat aaaattcctg
     3841 tttctcctct tgaataaatt aaaccttgca gcccacattg ggtgtaattt atttgccatc
     3901 atctcaggga agtatatccc aggttcccac ctccagataa ttaccctttc atttcaggca
     3961 ctcacagtgg aattgtccca cacaactatt tctgctggta aatctctctc tctggctact
     4021 tgtaacgcat tcacttttcc attgatgtag gtcaattgga taagtagata tttgatttga
     4081 ttgttcatat aacagaatta attatttcct ccatatctgg aagaacataa acaatgcata
     4141 ggaaagcaga gatcccttct caggtttcct gggttcttca tcctctaaat tcattcccat
     4201 ccacggccaa taaaacgtag aatgactcct acaaatcgta tatacaggta ctcagagaga
     4261 gagagttgaa atttgctgag tgcttactaa atttcaagtt ctattctgaa catttcatac
     4321 atgttaagcc attgaatccc tattgacaca gccattgagt ggaagctgac tcagcatggc
     4381 tcctgagact aaactcataa acactttgtg acatttcccc caagtgggcc cctgattagg
     4441 ttgaagtggg gaggttttat agtggcagcc aaatatacca cccagggaaa atactagaga
     4501 aactcaacat atgcctccca tttctgtcta ctggaagtat cccatgcctc catttttcta
     4561 ttgcacatct tccaaaatgt aggcccagaa gcagaggcca cagctatgcc tagaactaca
     4621 gaacaactgc cactggggtc aggctagtgt atgaaactgc aacaattagg ccagtaaaat
     4681 tttaggaatg aaaagttgac actatatctg tatattaagg gatacttgct ttacagaaat
     4741 atcagcaaat gaatcaaaaa tttacaggca ttttaccatt acaagggaaa ttcaagaaag
     4801 aatatgagaa ggagagattg tctgatcctc acccctattt ggttgcagtt acatcattag
     4861 cttcttcagg cattattggg tagtagagaa cagcaggaag cagggagaca aaaatcaaaa
     4921 tatcagttta ataatgttaa atcgacagat aatgttctgt tggaggacat ggctttgatc
     4981 tggtcctgtg gctgccccac agtgtacacc agaattagac aggctaaccc aggagaagca
     5041 ggcttgccct gttgcactaa ttgcgtagat gagagaaaat cagactacat gctccctgca
     5101 gggagacaga tcccaaagaa agagaaggaa gatcagaagg ccaagttctc ctgcctaatt
     5161 tttttcccag attcaccact cctttaaatc aggggtgtcc aatcttttgg cttccctggg
     5221 caacattgga agaatttgtc ttgggccaca caaaaaaaca cactaatgat agctgatgag
     5281 ctttaaaaaa atcacaaaaa aactcttaat gtgttaagga agtttacaaa tttgtattgg
     5341 tccacattca aagccgtcct gggccgcatg aagcccacgg gctgtgggtt gtgcaagctt
     5401 gctttacatc actcctacct tcctagaaag gactgagtga aggaggaggc acaaaacctg
     5461 catgccattt cagcgtaagt ccctctccag gaaaacagga ggaaaaggga aggaactccc
     5521 catacacata ctaagatctt taaggttact tcactctgat cctctaagaa gtcctaaact
     5581 gaagttccat ccacgactat gaggggccac tagaccagga gcctcatcta gtggaatcca
     5641 atttgtcagt atctccaggt ctcagtcaag gcctctttat gatgacgttg gtctcatcca
     5701 atgcttggat cttacaggat tattatgagc ccaaaaaaag aaaattgatt tttagaaatc
     5761 tcttagaaaa aatttaaaac attatataaa taccagggat tcctgttatt atcaaatgcc
     5821 acttccccca aggaagcatt cccagactcc ctggacctca ctaaatccct gggccaatct
     5881 cgccccattc ttgccctttg gtgtgaatca tcacagttgt aagttcatgc ttgagggtgg
     5941 ggtcacatct gtctcttcac aaatatattc tcagcatcta gaactgcctg atatacaaaa
     6001 cgcaataaat atgcattttt ggtcaattat tataattgat ctgttggaaa aaaatcaatt
     6061 atgtgaccca aattgtgacc attgtcacat gaaattgact cttgaactat aatattgttg
     6121 atgaaatttc tgtaatcgtt atcatacaag gactttgcat caaatttgat gttgatataa
     6181 tttagagaag gagcctttgg agattcctca gacttccctg tacacagttt catcacctcc
     6241 ttattagatg tgctatcata atgggtgtgt gtgtgtgtgt gtgaaaagga gagaaaaaac
     6301 atgcacacgt gttgcttagt aactttttaa taactcccat tgcatctgca actgccaact
     6361 tctccactga aaatatattt cctacaaata tccaatatta ctccctatgc taatcattat
     6421 agtagacttc ttattcagca tcagttagga acagtgtaaa ctgttcatgt gtttgggtga
     6481 agaagggcag agcagtgatg atggggaagt tgtcaggctc actttaccaa tgcaaaggta
     6541 ggtgagggcg tcctgaaaat tttgcacacc tacaaactta tgatttcaat agtgtctctg
     6601 aaaggcaaaa tgtccatttg caattctgga agtatatgtc atcttgaact agaagcttca
     6661 ggctgattaa gatctcctac ttctaaccta aaatactggg cttcctaaga cacattcaaa
     6721 taaggtaatt tttcaaaaat taaaactcat tccataaaca ttactaagcc cctaccatgt
     6781 gtaaaaaaat aataactagc atgatctctt tcttaaaagg tgattaaaag ttagatggca
     6841 gcaaaaagac aactatataa tgatattagg attatgataa tattaatacc ctacatttgt
     6901 ataatgcttt gaagtttgca gtattctctc atatgcatta agccatttaa ttgacttata
     6961 cagcaacata agtgaatagg ggatgtaaga tgaggctgaa aatggcgtaa aggaaaacaa
     7021 atacttgttg gggaactact gcacatcagg agttgcaaat ggacacccct ttgttcattc
     7081 atcttcaaaa agaattattg aataactgct atgttccagg taggagctgg ggatacaata
     7141 gtgacaaaag aaatccttgc cttcagggag tttacattgg gaggaaaagg cagacacaca
     7201 tagacccata aaggcaagga gtaaaaagtg ctagattatc acaagcaagc ctcactatgc
     7261 aaagtaaggt gtatgttccc catttcatgg aataaggtcc tggggttcat aaaggttaac
     7321 ttgctccggg tcacaagagg cacagtttaa aatactggaa cctgacttcg aaggctgtgc
     7381 tcttttgaac aagctaattc tatgttcaat catgcaaccc tgaggttaca aaatagaaag
     7441 gctatcgttt gatcctgacc tcacattgag cctgatagtc cagaaccttc taaggtgatt
     7501 gaccagaaga gtaggtggaa taatgttaat ctgaaagaga agtcaacagt aagtagattt
     7561 gacctcagtt cccagagacc tgagttggct gattccaggt tctcctctgg gtgcctccag
     7621 ccaatgcctc atggagccat aacacaccaa aagaaaaatt agagctgtct ttcccacaca
     7681 cccttttcca taataagtca gcttcttaga acaattttaa aaacaaaaaa cagaaaaata
     7741 caagatacat aatatcagag ctcaaattaa tggagaactt tttacttcaa attgtaaata
     7801 ggtataatac tttttctgat tttcataatc agaagccatt taaaatcatt tttttaatta
     7861 gacacaacag aacgtctttt taaaataaaa atgccaaaat ccaattacca acagataatg
     7921 gctactactg ttgtgatata ttaatacatc ttttcagact tctagccatg tagatatttt
     7981 tcccaaaaat aacatcatgt gacatattca gtgttttaat ctgtcactaa aaagaaatct
     8041 ttccatgttt aaaagtacaa ttctacgtta tcactttgaa tgtctgcaaa tacttaattg
     8101 tactattgtg ccatatttat tgaacaaatt ttctatatca gacgctaact taaattctaa
     8161 tttctactat ttgaaacagc aatgtgatga gctttgttta tatttaggac attaaacatt
     8221 tggtttatta actctttagc ataaattcct aaagtagaaa ttttgagtca cggggtttgt
     8281 acatattaca ttttgacaca tatttccaga atgaccccag aaatgctgcc tatgtgtgca
     8341 ctcctattaa tcatatgaaa gtgtcacttt ccccacatct atgccaacag tggacttttc
     8401 aacattggtt aatcttctag atgagaaatg atacctcatt gtaatttaat ttgtatttcc
     8461 ttttttcttt ctttctttcc cttttttaat agagacagga tcttcctatg ttgcccaggc
     8521 tggtctcaaa ctcatgagct caagagatcc tccctccttg gcctcctaat atatttatct
     8581 gatcaatagt tgattgactg tcttttcaca tg
//
