LOCUS       NM_001396057            4068 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens olfactory receptor family 56 subfamily B member 2
            (OR56B2), mRNA.
ACCESSION   NM_001396057
VERSION     NM_001396057.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4068)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131574.4.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000641377.2/ ENSP00000502530.1
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-87                AC131574.4         139769-139855       c
            88-4068             AC131574.4         131928-135908       c
FEATURES             Location/Qualifiers
     source          1..4068
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..4068
                     /gene="OR56B2"
                     /gene_synonym="OR11-63; OR56B2P"
                     /note="olfactory receptor family 56 subfamily B member 2"
                     /db_xref="GeneID:390073"
                     /db_xref="HGNC:HGNC:15246"
     exon            1..87
                     /gene="OR56B2"
                     /gene_synonym="OR11-63; OR56B2P"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..1037
                     /gene="OR56B2"
                     /gene_synonym="OR11-63; OR56B2P"
                     /note="olfactory receptor OR11-63; seven transmembrane
                     helix receptor; putative olfactory receptor 56B2;
                     olfactory receptor family 56 subfamily B member 2
                     pseudogene"
                     /codon_start=1
                     /product="olfactory receptor 56B2"
                     /protein_id="NP_001382986.1"
                     /db_xref="CCDS:CCDS91426.1"
                     /db_xref="GeneID:390073"
                     /db_xref="HGNC:HGNC:15246"
                     /translation="MVLQELRDSNSSKFQVSEFILMGFPGIHSWQHWLSLPLALLYLL
                     ALSANILILIIINKEAALHQPMYYFLGILAMADIGLATTIMPKILAILWFNAKTISLL
                     ECFAQMYAIHCFVAMESSTFVCMAIDRYVAICRPLRYPSIITESFVFKANGFMALRNS
                     LCLISVPLLAAQRHYCSQNQIEHCLCSNLGVTSLSCDDRRINSINQVLLAWTLMGSDL
                     GLIILSYALILYSVLKLNSPEAASKALSTCTSHLILILFFYTVIIVISITRSTGMRVP
                     LIPVLLNVLHNVIPPALNPMVYALKNKELRQGLYKVLRLE"
     exon            88..4068
                     /gene="OR56B2"
                     /gene_synonym="OR11-63; OR56B2P"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4047..4052
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR56B2"
                     /gene_synonym="OR11-63; OR56B2P"
                     /note="hexamer: AATAAA"
     polyA_site      4068
                     /gene="OR56B2"
                     /gene_synonym="OR11-63; OR56B2P"
                     /note="major polyA site"
ORIGIN      
        1 tatcctagtc catcttcagt ggctgtaaac cagctctggg tatactgaag atcactacat
       61 atgacaagtc tttcacagga caccacatgg tgctccagga gctcagagat tccaacagct
      121 ctaagttcca ggtctctgag tttatcctga tgggattccc tggcattcac agttggcagc
      181 actggctctc cctgcccctg gctctgctct acctcttagc tctcagtgcc aacatcctta
      241 tcctgatcat catcaacaaa gaggcagcac tgcaccagcc tatgtactat ttcctgggca
      301 tcttggctat ggcagacata ggcctggcta ccaccatcat gcctaagatt ttggccatct
      361 tatggttcaa tgctaagacc atcagtctcc tggagtgctt tgctcagatg tatgccatac
      421 attgctttgt ggccatggaa tcaagtacct ttgtctgcat ggctattgat agatatgtag
      481 ccatttgtcg accgctacga tatccatcaa tcatcactga atcttttgtt ttcaaagcaa
      541 acgggttcat ggcactgaga aacagcctgt gtctcatctc agtgcctctg ttggctgccc
      601 agaggcatta ctgctcccag aatcaaattg agcactgtct ttgttctaac cttggagtca
      661 ctagcctatc ttgtgatgat cgaagaatca atagcattaa ccaggtcctt ttggcttgga
      721 cactcatggg aagtgacctg ggtttgatta ttttatcata tgctctaata ctttactctg
      781 tcctgaagct gaactctcca gaagctgcat ccaaggcctt aagtacctgc acctcccacc
      841 tcatcttaat ccttttcttc tacacagtca tcattgtgat ttccattact cgtagtacag
      901 gaatgagagt tccccttatt ccagttctac ttaatgtgct acacaatgtc attccccctg
      961 ccctgaaccc catggtatat gcactcaaga acaaggaact caggcaaggc ttatacaagg
     1021 tacttagact ggagtgaagg gcacctgata tggaaaagat attcattttt tgaaaatttt
     1081 cttcacatgt ttttatatca tattctccaa ctgctgcaaa tggcagaaca acaaagaaat
     1141 agcataatga attggtggca acaactgaca ctttagaaca aaggagatag aagtaatatt
     1201 tgaaatattt gggagtcaag caaaaatctt catcacaaag ggtaacagtg atgctatttg
     1261 tctcaaggaa ttcaaagaaa agactaatgt aatctacatt tcatgttctt acccacttgt
     1321 cttagctaaa acttccagac agtgttgaat agaagtagtt agagcagata ttgtgtcaat
     1381 ctattccttt taattgaaga gcttaatatt ttacatttga tgtaataatt gataaaatag
     1441 gagatacttc tgcattttca tgatttgctt tattatgtgt cttatatttt taatttgcaa
     1501 aggacttgaa tagacatttc tctaagatta tatgcaaatg tccaaaaaat acatgaaaag
     1561 atgctcaaca taactagtca ttaatcatta ggcaaattca atcaaaacca caataacaca
     1621 cccctttacc ccctatatta tacaacacca caataacaca cccctttacc cccatattat
     1681 acatataaat gtactgcaaa tttatttttt tgcaataaga gattagtgtt tgcaagtata
     1741 tggatacact gaaatctcaa tacattgttg ggaagtaaaa atggcacagt ggctgtggaa
     1801 gagtttggca attactaaga aacttcagtg ccattaacat atgacccagg acccaacttt
     1861 taataataca cccaacataa ttgaaaaaaa tgttaataca aaaacctgta cacaaatgtt
     1921 tacagtagca ttattagcca aaaagtagaa acaacctgta tatctataag ctgtgtcttg
     1981 ttctgttttg tgttgttaca acagaatacc taatactgag ttagaaatat aggtttattt
     2041 agctcatagt tctgcaggca gggtacttca aggacatgtc cctggcttca tctgaggact
     2101 ttggtgttgc ctcataacat ggcagacaag gtcaaaggga aaacagacat gtgcaaagag
     2161 acaaaaccca acgggcttcc cagctttata acaactcact gtcatgacaa atccatctcc
     2221 cagagaactg atccagttat gtaacagaga aaactcagta actgccacaa gaatagcacc
     2281 aagtcattca tgaggaatcc atccccagga cccaaacatc tcttactggg ccccacttcc
     2341 caataccact acagtgggga tcaaatttca acctgatttt tggtggagac aagcaaaccc
     2401 tatccacacc atagcagcta ctgaatggat aaacaaaatt aagtgtatct atactaggaa
     2461 ttattattta ataaaaagta cctatatgag atgatagata tactaatcag cttcactata
     2521 ataattattt tgctgtctct atcccataat ttcatgctgt aaatctcaaa tatatataga
     2581 ataaaactta tcttacaaaa attcaacttg attgaattaa aaattgctaa atttaacaaa
     2641 atgacatgga aaattttgta tagtaaagag gaaaaatata aaaagaataa attctcccaa
     2701 caacaaacaa acaaaagtaa atgaagtact cgtacaatct gcagcataca tgaactttga
     2761 aaacattatg cttaggttag tgaagaaagc caaacacaaa aggccaccta gtatctgatt
     2821 ccatttgtat gaatatccag aataggttaa gtctatagaa aaaaaaagca aattagttgt
     2881 tagtagggaa tggagactcc aggcaataat gagagactaa ctaatagtta tgaagtttcc
     2941 ttttgaggta atggaaatat tgtgaaatta gatagtggca atggttgcac agcataatga
     3001 atgtagtgaa agtcacccaa ttgtacgttt tcttttttca ttttatataa aattaagggg
     3061 tacaactgct ttttgataca tggatgtata tccatgtata gcctggctgt ggtgaagtct
     3121 gggcttgtag tgtacccacc atagtgggta ccaccagcat agtgtatatt gtacctacta
     3181 aggaatttct cattcctcat tccccttcca tctgcccatc ccccaaatct ccaatattta
     3241 tctatttcac actctatgcc tatgtgtaca cattaggtag ttcccactta aaagtgagaa
     3301 catgtggtat ttgcttttct gtttctgaga tatttcactt aaaataatgg cctcataatc
     3361 tatgcacgtt gctgcaaaaa acattatttc atttgttttc ttgactgagg agtattccat
     3421 tgtatatcat accacatttt ttttatccag tcatctgttg atggacacag gttgattccg
     3481 tatctttccc tgtgataaac atactagtgc caatattttt aagtgtaatt attttaaatg
     3541 caattatctt cttttgggta gatacctagg attggcattg ctggatggaa tggtagttct
     3601 agttttagtt tcttgaatat ttccgtactg ttttccatag aggtcgtact aatttacatt
     3661 caatataaaa caatataaaa aactgcaaaa attattctct acatgtatat ttgttatata
     3721 actttctgta aattaaaaga acatagatgt ctgagaacag gaaaatactt aaggaagtgt
     3781 gtaaaacaca taatgtgcct ttatttaatc ataatactga acaatccttt tttgaatgtg
     3841 cttaatataa acattaactg aaaatgatag aatttttgtt taaaatttga tgttatccaa
     3901 acgtttgtca aaagtatata tagaaattgt atataaaaga aaaagtatca gaagttacct
     3961 ctacattata gaattaggtt ctaattatct ctgtgatgtc ctcattttta tttttacact
     4021 taataaaaac aaacattttt cttctaaata aaaatacata aaattaga
//
