LOCUS       NM_001005180            2076 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 56 subfamily B member 1
            (OR56B1), mRNA.
ACCESSION   NM_001005180 XM_370605
VERSION     NM_001005180.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2076)
  AUTHORS   Denoeud,F., Kapranov,P., Ucla,C., Frankish,A., Castelo,R.,
            Drenkow,J., Lagarde,J., Alioto,T., Manzano,C., Chrast,J., Dike,S.,
            Wyss,C., Henrichsen,C.N., Holroyd,N., Dickson,M.C., Taylor,R.,
            Hance,Z., Foissac,S., Myers,R.M., Rogers,J., Hubbard,T., Harrow,J.,
            Guigo,R., Gingeras,T.R., Antonarakis,S.E. and Reymond,A.
  TITLE     Prominent use of distal 5' transcription start sites and discovery
            of a large number of additional exons in ENCODE regions
  JOURNAL   Genome Res 17 (6), 746-759 (2007)
   PUBMED   17567994
REFERENCE   2  (bases 1 to 2076)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK122668.1 and AC131574.4.
            
            On May 17, 2019 this sequence version replaced NM_001005180.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK122668.1, BC137184.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000317121.6/ ENSP00000322939.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-384               AK122668.1         1-384
            385-611             AC131574.4         163950-164176       c
            612-1091            AK122668.1         612-1091
            1092-2076           AC131574.4         162485-163469       c
FEATURES             Location/Qualifiers
     source          1..2076
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..2076
                     /gene="OR56B1"
                     /gene_synonym="OR11-65; OR56B1P"
                     /note="olfactory receptor family 56 subfamily B member 1"
                     /db_xref="GeneID:387748"
                     /db_xref="HGNC:HGNC:15245"
     exon            1..2076
                     /gene="OR56B1"
                     /gene_synonym="OR11-65; OR56B1P"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..1044
                     /gene="OR56B1"
                     /gene_synonym="OR11-65; OR56B1P"
                     /note="olfactory receptor, family 56, subfamily B, member
                     1 pseudogene; olfactory receptor OR11-65"
                     /codon_start=1
                     /product="olfactory receptor 56B1"
                     /protein_id="NP_001005180.1"
                     /db_xref="CCDS:CCDS31395.1"
                     /db_xref="GeneID:387748"
                     /db_xref="HGNC:HGNC:15245"
                     /translation="MNHMSASLKISNSSKFQVSEFILLGFPGIHSWQHWLSLPLALLY
                     LSALAANTLILIIIWQNPSLQQPMYIFLGILCMVDMGLATTIIPKILAIFWFDAKVIS
                     LPECFAQIYAIHFFVGMESGILLCMAFDRYVAICHPLRYPSIVTSSLILKATLFMVLR
                     NGLFVTPVPVLAAQRDYCSKNEIEHCLCSNLGVTSLACDDRRPNSICQLVLAWLGMGS
                     DLSLIILSYILILYSVLRLNSAEAAAKALSTCSSHLTLILFFYTIVVVISVTHLTEMK
                     ATLIPVLLNVLHNIIPPSLNPTVYALQTKELRAAFQKVLFALTKEIRS"
     regulatory      2056..2061
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR56B1"
                     /gene_synonym="OR11-65; OR56B1P"
                     /note="hexamer: ATTAAA"
     polyA_site      2076
                     /gene="OR56B1"
                     /gene_synonym="OR11-65; OR56B1P"
                     /note="major polyA site"
ORIGIN      
        1 ttctgtggtg gttccaacct gtgataactg agaacaatac aaatagagat ttgaaattca
       61 tgttgaatca tgaatcatat gtctgcatct ctcaaaatct ccaatagctc caaattccag
      121 gtctctgagt tcatcctgct gggattcccg ggcattcaca gctggcaaca ctggctatct
      181 ctgcccctgg cactactgta tctctcagca cttgctgcaa acaccctcat cctcatcatc
      241 atctggcaga acccttcttt acagcagccc atgtatattt tccttggcat cctctgtatg
      301 gtagacatgg gtctggccac tactatcatc cctaagatcc tggccatctt ctggtttgat
      361 gccaaggtta ttagcctccc tgagtgcttt gctcagattt atgccattca cttctttgtg
      421 ggcatggagt ctggtatcct actctgcatg gcttttgata gatatgtggc tatttgtcac
      481 cctcttcgct atccatcaat tgtcaccagt tccttaatct taaaagctac cctgttcatg
      541 gtgctgagaa atggcttatt tgtcactcca gtgcctgtgc ttgcagcaca gcgtgattat
      601 tgctccaaga atgaaattga acactgcctg tgctctaacc ttggggtcac aagcctggct
      661 tgtgatgaca ggaggccaaa cagcatttgc cagttggttc tggcatggct tggaatgggg
      721 agtgatctaa gtcttattat actgtcatat attttgattc tgtactctgt acttagactg
      781 aactcagctg aagctgcagc caaggccctg agcacttgta gttcacatct caccctcatc
      841 cttttctttt acactattgt tgtagtgatt tcagtgactc atctgacaga gatgaaggct
      901 actttgattc cagttctact taatgtgttg cacaacatca tccccccttc cctcaaccct
      961 acagtttatg cacttcagac caaagaactt agggcagcct tccaaaaggt gctgtttgcc
     1021 cttacaaaag aaataagatc ttagagacct tctccatgat gtacatgaac ctcagcttct
     1081 cctaaactgg atagtaaaat ttcaaagagg ataaatgagt aagtgaatac ctttgggatt
     1141 ccctttttat atttgtatgt aaataattgt gaaagcttca gaaaagatac aaaaaatcac
     1201 agtagcctaa aatattgaca aaagctaaat atttaaatat atttgagaat atggaagaaa
     1261 tttctgccaa atcaaattgg atttaaagaa cttaatgatt gatatctatc tcttaaaata
     1321 aaaatgaata taatcacaca cccacaaata cacacacaga cacacataca ttcaatcaga
     1381 caaatgagtg attgggacat gaatcacagg tcatgcttgc gcattgttag ctgtaacttg
     1441 ggagctgtaa cttgggagca aagtcagtct gcctaaacaa gcattactcc agtaatatga
     1501 aatacagagg tcggaaaaga aaataattca gataaagcca aatcagtcaa tgatgaggat
     1561 ttatgtggaa tatgagatga ctcagcttgg acagacagaa cccaaaagat tcatctagct
     1621 agaaggatct ggtgcttacg ccgtttgcct ccccagattt gctgtctgcc ctttgtgcac
     1681 tgctctgtaa actggagggc tgactttcac atattgtaag cccaaactcc tttgtctttc
     1741 ggtgttcagt tgaattgagc caatgtgatg cgtgacagat tatagttcaa gaggagacag
     1801 catttgggct atttattatt ctactcccag cctgctttga catgagggtt ttcactggat
     1861 atgtcccttc tctggccacc cacctgctac agctacagct tttatggaaa tatagtaaca
     1921 ggcttgtctt gccttctttc ttcaggccaa ggggctgata aaggcttcct gatagtagtc
     1981 tctgagtgcc cagcatccat tattttttaa tatccacttg ttttcttaaa caacctacta
     2041 ctcaatacca acttcattaa attgtcttca aactca
//
