LOCUS       NM_001005177             948 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 52 subfamily R member 1
            (OR52R1), mRNA.
ACCESSION   NM_001005177 XM_061627
VERSION     NM_001005177.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 948)
  AUTHORS   Olender,T., Waszak,S.M., Viavant,M., Khen,M., Ben-Asher,E.,
            Reyes,A., Nativ,N., Wysocki,C.J., Ge,D. and Lancet,D.
  TITLE     Personal receptor repertoires: olfaction as a model
  JOURNAL   BMC Genomics 13, 414 (2012)
   PUBMED   22908908
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 948)
  AUTHORS   Menashe,I., Aloni,R. and Lancet,D.
  TITLE     A probabilistic classifier for olfactory receptor pseudogenes
  JOURNAL   BMC Bioinformatics 7, 393 (2006)
   PUBMED   16939646
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 948)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC103710.2.
            
            On Dec 15, 2009 this sequence version replaced NM_001005177.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jun 2015].
            
            Sequence Note: This gene is a segregating pseudogene. This RefSeq
            represents the protein encoded by the reference genome allele,
            which is predicted to be non-functional as an olfactory receptor
            according to the Classifier for Olfactory Receptor Pseudogenes.
            This RefSeq was derived from genomic sequence to make the sequence
            consistent with the reference genome assembly. The genomic
            coordinates used for the transcript record were based on
            alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000624978.1/ ENSP00000485292.1
            polymorphic pseudogene :: PMID: 22908908
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-948               AC103710.2         44234-45181
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..948
                     /gene="OR52R1"
                     /gene_synonym="OR11-22"
                     /note="olfactory receptor family 52 subfamily R member 1"
                     /db_xref="GeneID:119695"
                     /db_xref="HGNC:HGNC:15235"
     CDS             1..948
                     /gene="OR52R1"
                     /gene_synonym="OR11-22"
                     /note="olfactory receptor OR11-22"
                     /codon_start=1
                     /product="olfactory receptor 52R1"
                     /protein_id="NP_001005177.3"
                     /db_xref="GeneID:119695"
                     /db_xref="HGNC:HGNC:15235"
                     /translation="MVLASGNSSSHPVSFILLGIPGLESFQLWIAFPFCATYAVAVVG
                     NITLLHVIRIDHTLHEPMYLFLAMLAITDLVLSSSTQPKMLAIFWFHAHEIQYHACLI
                     QVFFIHAFSSVESGVLMAMALDCYVAICFPLRHSSILTPSVVIKLGTIVMLRGLLWVS
                     PFCFMVSRMPFCQHQAIPQSYCEHMAVLKLVCADTSISRGNGLFVAFSVAGFDMIVIG
                     MSYVMILRAVLQLPSGEARLKAFSTRSSHICVILALYIPALFSFLTYRFGHDVPRVVH
                     ILFANLYLLIPPMLNPIIYGVRTKQIGDRVIQGCCGNIP"
     exon            1..948
                     /gene="OR52R1"
                     /gene_synonym="OR11-22"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggtgctgg cttcagggaa cagctcttct catcctgtgt ccttcatcct gcttggaatc
       61 ccaggcctgg agagtttcca gttgtggatt gcctttccgt tctgtgccac gtatgctgtg
      121 gctgttgttg gaaatatcac tctcctccat gtaatcagaa ttgaccacac cctgcatgag
      181 cccatgtacc tctttctggc catgctggcc atcactgacc tggtcctctc ctcctccact
      241 caacctaaga tgttggccat attctggttt catgctcatg agattcagta ccatgcctgc
      301 ctcatccagg tgttcttcat ccatgccttt tcttctgtgg agtctggggt gctcatggct
      361 atggccctgg actgctacgt ggctatctgc ttcccactcc gacactctag catcctgacc
      421 ccatcggtcg tgatcaaact ggggaccatc gtgatgctga gagggctgct gtgggtgagc
      481 cccttctgct tcatggtgtc taggatgccc ttctgccaac accaagccat tccccagtca
      541 tactgtgagc acatggctgt gctgaagttg gtgtgtgctg atacaagcat aagtcgtggg
      601 aatgggctct ttgtggcctt ctctgtggct ggctttgata tgattgtcat tggtatgtca
      661 tacgtgatga ttttgagagc tgtgcttcag ttgccctcag gtgaagcccg cctcaaagct
      721 tttagcacac gttcctccca tatctgtgtc atcttggctc tttatatccc agcccttttt
      781 tctttcctca cctaccgctt tggccatgat gtgccccgag ttgtacacat cctgtttgct
      841 aatctctatc tactgatacc tcccatgctc aaccccatca tttatggagt tagaaccaaa
      901 cagatcgggg acagggttat ccaaggatgt tgtggaaaca tcccctga
//
