LOCUS       NM_001005175            1329 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 52 subfamily N member 4
            (OR52N4), mRNA.
ACCESSION   NM_001005175 XM_372361
VERSION     NM_001005175.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1329)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131574.4.
            
            On Aug 30, 2020 this sequence version replaced NM_001005175.4.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2145245,
                              SAMEA2151119 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641350.2/ ENSP00000493338.1
            polymorphic pseudogene :: based on alignments, homology
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                AC131574.4         146703-146765       c
            64-1329             AC131574.4         145050-146315       c
FEATURES             Location/Qualifiers
     source          1..1329
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..1329
                     /gene="OR52N4"
                     /gene_synonym="OR11-64"
                     /note="olfactory receptor family 52 subfamily N member 4"
                     /db_xref="GeneID:390072"
                     /db_xref="HGNC:HGNC:15230"
     exon            1..63
                     /gene="OR52N4"
                     /gene_synonym="OR11-64"
                     /inference="alignment:Splign:2.1.0"
     exon            64..1329
                     /gene="OR52N4"
                     /gene_synonym="OR11-64"
                     /inference="alignment:Splign:2.1.0"
     CDS             112..1077
                     /gene="OR52N4"
                     /gene_synonym="OR11-64"
                     /note="olfactory receptor OR11-64"
                     /codon_start=1
                     /product="olfactory receptor 52N4"
                     /protein_id="NP_001005175.3"
                     /db_xref="CCDS:CCDS44528.1"
                     /db_xref="GeneID:390072"
                     /db_xref="HGNC:HGNC:15230"
                     /translation="MLTLNKTDLIPASFILNGVPGLEDTQLWISFPFCSMYVVAMVGN
                     CGLLYLIHYEDALHKPMYYFLAMLSFTDLVMCSSTIPKALCIFWFHLKDIGFDECLVQ
                     MFFTHTFTGMESGVLMLMALDRYVAICYPLRYSTILTNPVIAKVGTATFLRGVLLIIP
                     FTFLTKLLPYCRGNILPHTYCDHMSVAKLSCGNVKVNAIYGLMVALLIWGFDILCITN
                     SYTMILRAVVSLSSADARQKAFNTCTAHICAIVFSYTPAFFSFFSHRFGEHIIPPSCH
                     IIVANIYLLLPPTMNPIVYGVKTKQIRDCVIRILSGSKDTKSYSM"
     regulatory      1304..1309
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR52N4"
                     /gene_synonym="OR11-64"
                     /note="hexamer: ATTAAA"
     polyA_site      1329
                     /gene="OR52N4"
                     /gene_synonym="OR11-64"
                     /note="major polyA site"
ORIGIN      
        1 tcagtcagtc attaagaata aaaattaaaa agtcaacatc tcatctctca gatcatcagt
       61 gaggaaagcc cagacaaatt ttgagctatt tcataaccta ccagacttat catgctaaca
      121 ctgaataaaa cagacctaat accagcttca tttattctga atggagtccc aggactggaa
      181 gacacacaac tctggatttc cttcccattc tgctctatgt atgttgtggc tatggtaggg
      241 aattgtggac tcctctacct cattcactat gaggatgccc tgcacaaacc catgtactac
      301 ttcttggcca tgctttcctt tactgacctt gttatgtgct ctagtacaat ccctaaagcc
      361 ctctgcatct tctggtttca tctcaaggac attggatttg atgaatgcct tgtccagatg
      421 ttcttcaccc acaccttcac agggatggag tctggggtgc ttatgcttat ggccctggat
      481 cgctatgtgg ccatctgcta ccccttacgc tattcaacta tcctcaccaa tcctgtaatt
      541 gcaaaggttg ggactgccac cttcctgaga ggggtattac tcattattcc ctttactttc
      601 ctcaccaagc tcctgcccta ctgcagaggc aatatacttc cccataccta ctgtgaccac
      661 atgtctgtag ccaaattgtc ctgtggtaat gtcaaggtca atgccatcta tggtctgatg
      721 gttgccctcc tgatttgggg ctttgacata ctgtgtatca ccaactccta taccatgatt
      781 ctccgggcag tggtcagcct ctcctcagca gatgctcggc agaaggcctt taatacctgc
      841 actgcccaca tttgtgccat tgttttctcc tatactccag ctttcttctc cttcttttcc
      901 caccgctttg gggaacacat aatcccccct tcttgccaca tcattgtagc caatatttat
      961 ctgctcctac cacccactat gaaccctatt gtctatgggg tgaaaaccaa acagatacga
     1021 gactgtgtca taaggatcct ttcaggttct aaggatacca aatcctacag catgtgaatg
     1081 aacacttgcc aggagtgaga agagaaggaa agaattactt ctatttgcct cttatgcagg
     1141 agttcataaa atctttctgg aagcactgta ttgatcacaa aatggagttt gttaactggt
     1201 gcattctcaa taagtacctt gggaatctca acatcattgg aaggcccacc aacatttcta
     1261 taaatttttt accttctcac tcatgtgaag gaccagtcta ataattaaac catattttat
     1321 tcgacaaaa
//
