LOCUS       NM_001005174            1333 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 52 subfamily N member 2
            (OR52N2), mRNA.
ACCESSION   NM_001005174 XM_011520090 XM_372365
VERSION     NM_001005174.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1333)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131574.4.
            
            On Dec 11, 2020 this sequence version replaced NM_001005174.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803615.381044.1,
                                           DRR138512.450232.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2148874, SAMEA2151119
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000317037.3/ ENSP00000322801.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-131               AC131574.4         91954-92084         c
            132-1333            AC131574.4         79525-80726         c
FEATURES             Location/Qualifiers
     source          1..1333
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..1333
                     /gene="OR52N2"
                     /gene_synonym="OR11-57"
                     /note="olfactory receptor family 52 subfamily N member 2"
                     /db_xref="GeneID:390077"
                     /db_xref="HGNC:HGNC:15228"
     exon            1..131
                     /gene="OR52N2"
                     /gene_synonym="OR11-57"
                     /inference="alignment:Splign:2.1.0"
     exon            132..1333
                     /gene="OR52N2"
                     /gene_synonym="OR11-57"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..1151
                     /gene="OR52N2"
                     /gene_synonym="OR11-57"
                     /note="olfactory receptor OR11-57"
                     /codon_start=1
                     /product="olfactory receptor 52N2"
                     /protein_id="NP_001005174.1"
                     /db_xref="CCDS:CCDS31399.1"
                     /db_xref="GeneID:390077"
                     /db_xref="HGNC:HGNC:15228"
                     /translation="MSGDNSSSLTPGFFILNGVPGLEATHIWISLPFCFMYIIAVVGN
                     CGLICLISHEEALHRPMYYFLALLSFTDVTLCTTMVPNMLCIFWFNLKEIDFNACLAQ
                     MFFVHMLTGMESGVLMLMALDRYVAICYPLRYATILTNPVIAKAGLATFLRNVMLIIP
                     FTLLTKRLPYCRGNFIPHTYCDHMSVAKVSCGNFKVNAIYGLMVALLIGVFDICCISV
                     SYTMILQAVMSLSSADARHKAFSTCTSHMCSIVITYVAAFFTFFTHRFVGHNIPNHIH
                     IIVANLYLLLPPTMNPIVYGVKTKQIQEGVIKFLLGDKVSFTYDK"
     regulatory      1285..1290
                     /regulatory_class="polyA_signal_sequence"
                     /gene="OR52N2"
                     /gene_synonym="OR11-57"
                     /note="hexamer: AATAAA"
     polyA_site      1305
                     /gene="OR52N2"
                     /gene_synonym="OR11-57"
                     /note="major polyA site"
ORIGIN      
        1 ggtcaccgcg gtattgcaag cctctcctcc tcgcgttgct gagagtccga gtttattcat
       61 cacaatgggt gggtcccgat ctcccctccc tgagactacc gcaacggggc attggaatgc
      121 gtctcccctg ggcagaaagc aatggctgct aaagagtata aaatgctctc ctcctgtcag
      181 ccatcatgtc tggggacaac agctccagcc tgaccccagg attctttatc ttgaatggcg
      241 ttcctgggct ggaagccaca cacatctgga tctccctgcc attctgcttt atgtacatca
      301 ttgctgtcgt ggggaactgt gggctcatct gcctcatcag ccatgaggag gccctgcacc
      361 ggcccatgta ctacttcctg gccctgctct ccttcactga tgtcaccttg tgcaccacca
      421 tggtacctaa tatgctgtgc atattctggt tcaacctcaa ggagattgac tttaacgcct
      481 gcctggccca gatgtttttt gtccatatgc tgacagggat ggagtctggg gtgctcatgc
      541 tcatggccct ggaccgctat gtggccatct gctacccctt acgctatgcc accatcctta
      601 ccaaccctgt catcgccaag gctggtcttg ccaccttctt gaggaatgtg atgctcatca
      661 tcccattcac tctcctcacc aagcgcctgc cctattgccg ggggaacttc atcccccaca
      721 cctactgtga ccatatgtct gtggccaagg tatcctgtgg caatttcaag gtcaatgcta
      781 tttatggtct gatggttgct ctcctgattg gtgtgtttga tatctgctgt atctctgtat
      841 cttacactat gattttgcag gctgttatga gcctgtcatc agcagatgct cgtcacaaag
      901 ccttcagcac ctgcacatct cacatgtgtt ccattgtgat cacctatgtt gctgcttttt
      961 tcactttttt cactcatcgt tttgtaggac acaatatccc aaaccacata cacatcatcg
     1021 tggccaacct ttatctgcta ctgcctccta ccatgaaccc aattgtttat ggagtcaaga
     1081 ccaagcagat tcaggaaggt gtaattaaat ttttacttgg agacaaggtt agttttacct
     1141 atgacaaatg aaacatagaa tagacatatt gtttcaggtg gtgagaaaat aatggagaca
     1201 aaatttcata aaagatgtga ataaaatggt attaaaatca tgacatgtaa tttacccatg
     1261 taacaaactt gcacgtgtac ctaaaataaa aatagaaata aaaaatcaaa ataaagacat
     1321 aaatttgtaa gtc
//
