LOCUS       NM_001405760            6591 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 52 subfamily I member 2
            (OR52I2), mRNA.
ACCESSION   NM_001405760
VERSION     NM_001405760.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6591)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 6591)
  AUTHORS   Vanti,W.B., Nguyen,T., Cheng,R., Lynch,K.R., George,S.R. and
            O'Dowd,B.F.
  TITLE     Novel human G-protein-coupled receptors
  JOURNAL   Biochem Biophys Res Commun 305 (1), 67-71 (2003)
   PUBMED   12732197
  REMARK    GeneRIF: This publication uses 'GPR133' as a name for this gene.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC090719.8.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000641896.1/
                                                ENSP00000493402.1
            RefSeq Select criteria           :: based on manual assertion,
                                                conservation, expression,
                                                longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-122               AC090719.8         126972-127093       c
            123-6591            AC090719.8         115496-121964       c
FEATURES             Location/Qualifiers
     source          1..6591
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..6591
                     /gene="OR52I2"
                     /gene_synonym="OR11-12; OR52I1"
                     /note="olfactory receptor family 52 subfamily I member 2"
                     /db_xref="GeneID:143502"
                     /db_xref="HGNC:HGNC:15221"
     exon            1..122
                     /gene="OR52I2"
                     /gene_synonym="OR11-12; OR52I1"
                     /inference="alignment:Splign:2.1.0"
     exon            123..6591
                     /gene="OR52I2"
                     /gene_synonym="OR11-12; OR52I1"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..1116
                     /gene="OR52I2"
                     /gene_synonym="OR11-12; OR52I1"
                     /note="olfactory receptor OR11-12"
                     /codon_start=1
                     /product="olfactory receptor 52I2"
                     /protein_id="NP_001392689.1"
                     /db_xref="GeneID:143502"
                     /db_xref="HGNC:HGNC:15221"
                     /translation="MLGPAYNHTMETPASFLLVGIPGLQSSHLWLAISLSAMYIIALL
                     GNTIIVTAIWMDSTRHEPMYCFLCVLAAVDIVMASSVVPKMVSIFCSGDSSISFSACF
                     TQMFFVHLATAVETGLLLTMAFDRYVAICKPLHYKRILTPQVMLGMSMAITIRAIIAI
                     TPLSWMVSHLPFCGSNVVVHSYCEHIALARLACADPVPSSLYSLIGSSLMVGSDVAFI
                     AASYILILKAVFGLSSKTAQLKALSTCGSHVGVMALYYLPGMASIYAAWLGQDVVPLH
                     TQVLLADLYVIIPATLNPIIYGMRTKQLRERIWSYLMHVLFDHSNLGS"
ORIGIN      
        1 gtcatttttt cctgctcctc ttgaagagtc ctgtacaaat ccctcttctt ctgagtaaaa
       61 gaaatgtaga ctaccaggca tcaacccatc agggaaagtt gaatagagaa gattccaagg
      121 atgaaaaaag tctcacttgt gatgctgggt ccagcttata accacacaat ggaaacccct
      181 gcctccttcc tccttgtggg tatcccagga ctgcaatctt cacatctttg gctggctatc
      241 tcactgagtg ccatgtacat catagccctg ttaggaaaca ccatcatcgt gactgcaatc
      301 tggatggatt ccactcggca tgagcccatg tattgctttc tgtgtgttct ggctgctgtg
      361 gacattgtta tggcctcctc ggtggtaccc aagatggtga gcatcttctg ctcaggagac
      421 agctcaatca gctttagtgc ttgtttcact cagatgtttt ttgtccactt agccacagct
      481 gtggagacgg ggctgctgct gaccatggct tttgaccgct atgtagccat ctgcaagcct
      541 ctacactaca agagaattct cacgcctcaa gtgatgctgg gaatgagtat ggccatcacc
      601 atcagagcta tcatagccat aactccactg agttggatgg tgagtcatct acctttctgt
      661 ggctccaatg tggttgtcca ctcctactgt gagcacatag ctttggccag gttagcatgt
      721 gctgaccccg tgcccagcag tctctacagt ctgattggtt cctctcttat ggtgggctct
      781 gatgtggcct tcattgctgc ctcctatatc ttaattctca aggcagtatt tggtctctcc
      841 tcaaagactg ctcagttgaa agcattaagc acatgtggct cccatgtggg ggttatggct
      901 ttgtactatc tacctgggat ggcatccatc tatgcggcct ggttggggca ggatgtagtg
      961 cccttgcaca cccaagtcct gctagctgac ctgtacgtga tcatcccagc caccttaaat
     1021 cccatcatct atggcatgag gaccaaacaa ctgcgggaga gaatatggag ttatctgatg
     1081 catgtcctct ttgaccattc caacctgggt tcatgaacac aatatctgtt cagatccagc
     1141 caatttcaaa gatgccttag agatctgcag agcttagttt acctggtgct acaggaattc
     1201 taagatgaag gtgtaaagga tatccttgca taacttttca attactagca ggaatgtgaa
     1261 tgaaatgttt ctgattttct gagggctttc tcagtggatt caatcaactt gtatctgaat
     1321 cagagacaag ttttggtaga gaatacacat ttgattgaac ttatgtttcc ctgctcttta
     1381 ggaatgtgct aggttaggct gaggaaggca caaagcctct tcctgctcct gcctcaccaa
     1441 ctcttaaaat gaaagacaac aaagaccgct caccattctc ttcatgaaca gctatgtgtc
     1501 cacttaggat ctggggaact gagagcatgc aactctattt cttagttttt catacttcca
     1561 aatagttatc tacccttcgc cattaaaaag aaaaacacta gaaactttat agcttgtgcc
     1621 tgttgactct tttctgccaa ctttattcct ttccacagat gatgctcagg cagaagacat
     1681 gaactttaaa acatggcccc atgcacccct ctagcctctt gtattttcaa tccctttcaa
     1741 gtcccctgac tctactgcct ctggtttatc ctctatttgg agaatatgtc ccttctcata
     1801 cttttgtgct caggtgcatg ccctatctcc agttgaaaaa ctcatcttcc ttgccctccc
     1861 ctacatcctc tttcccttct ccgttcaaca ggatgctata acagcgtcat gggaaacatc
     1921 taaccagtga aacctggccc gagtccccag gcagaactga ggaaatgtga actcgacttt
     1981 gagatatgaa gtacactgtc agtgtgaata gttctaccat aaagtgaagt gaaatacggt
     2041 tattagaatt tagctcttga ctttctggct tacttgcttt gtgactttta tgagcctcag
     2101 ctttcatcta taagatgttg atgtgatgat ggcagctact tcaggaggtt ttgaaaactg
     2161 actgagataa tctttgaaaa gagcatttgt tatgatgcct ggcacttagt gaactttcac
     2221 aaatcctacc tatcatggtt ttttgtttgt ttgtttgttt tcctttcagg atacacttta
     2281 tactcttagt ctaactttta ggtatcctct gaaaacttga agaaacagac tcttcagcca
     2341 gtaagcatct gcctcctcct gctatctgga aatccccagg ggccagagca caaagataaa
     2401 ccagtctctt gaggagtagc aatgtttggt tgctgggtag aggccaaagg aaggtgggtg
     2461 tccagggaca aggcaggatg attgagtatc cagagggaaa agagggcccc aatgagaagt
     2521 ctttggaaag gacaatatga ctctccattg tttgttcgta tttgattgtg tttgcacttc
     2581 ctgctcctcc gaaggtatcc tgtattaacc cctcttcttt tgcgtgaaag aaatgtggac
     2641 tatgaggcat ggactcattg gagaaagtta aacagagaaa actctcagac tgtgggtaac
     2701 tgacttgggc attagtgttg ggctgatgga gtctgaaggc cagatcaccc cagaatagaa
     2761 aatataagcc tttactcttc ctatacaggg ctgtctaggt gtggtgggta ttactgatac
     2821 caagaatgta tgaaaatgat atttggatag gaaaggtggg agagagaatg ggacatataa
     2881 ttaattgaaa gcagagagga aggggtaggt atgatattgg catggtggag agacagtttt
     2941 atgggactaa gaacagttat gaggaaaaaa acccagtagt agggctgatt gggtgcatgt
     3001 ttggctgaag aggggaagta tccaggtagg aagaaagggt tatcataaac agaaaggctt
     3061 gattcaaatg catatgcctt agttctttta cctttaagac attttcattt tgaattatgt
     3121 attcctcact cttttaatag aaatgaaaca ttctcccata tcttatgatt tgtgaatcat
     3181 gagttgttga aattaaggga cttttctgtg ctagttttaa gtaattggct ctccaggtct
     3241 gcatgtgaat atccccacag tattgaaggc aaaggcaggt gcagggctga aaatagatct
     3301 taggataact taccagagct ttctgaaaac agtaaacatt aacaaccaga gggcactggt
     3361 gtctgtatct taacctcagt agtgcctatg taggtgtgtt catgtgttca cataataaat
     3421 atttatcagg ctatctatct gagatttgtg catttcccat tatattcata gtgttttaaa
     3481 aagttaatga aaaatcaggg agcaggcagt tgtgttaaat gttttggaga tgtcaagtaa
     3541 aacaaaagga aaaagagtta ctggactggc aacagatgct tgatggagat caacgttaat
     3601 cttagccaaa caatgttcag tatcaatagg ctgattgaaa taaatatttg tagaaagaaa
     3661 caactaacca aaccgagtgt cctgttcttt gcaaagactg acaatgtaaa tctccagcaa
     3721 cgctaattga gaagaaacgt aaatggagat taaaaagaaa aacactctca agggcatgaa
     3781 aggtatgccc aattagagct tccagggctg aggcctcagc atcagctgag gctgcctctt
     3841 gaagaaaggt gaatttaaac agggcagcca ggggaggaac attctggatc agaggtgagt
     3901 ggggaagagg ctgtttggat tctcaagctt tatgcagccc tttatgcaat aatgcacaag
     3961 tctgagtttg ttgcatccag aacacatgcg gcaatctcaa gcataccctg attttttctt
     4021 tcactcttca ctaccgttct acttcaaaag ctttcccttg tcttctcatg atctatcact
     4081 gaagatgtct cacccagtag ctacacagca aggtttttat aatctgatta tgatgtggat
     4141 atcactaatt tattcaatct gtgccatgat atagtatttc ttaagctcag ggattttatt
     4201 tttggtttgt ttcatataga tcacagtctg taatcatgtc tccaaaactt gattttttaa
     4261 ataaaactcc tgaggacttt accacagctg ctggtggtac ctaactatgg agcccatcag
     4321 tgctaggctc tgtaggaggt gaactgaagg agcaaatgta tgtcccagga ttaggattga
     4381 gaacctgacg aatgctcacc taatgcttgg ctaagagaga aaatgtgtac cacagcagat
     4441 gggatcaagg cacagaattc cattaatctg atttattcca ctactcagag aggagccaga
     4501 accctgacaa gaggtaaaaa gaggtagctt gagacagtat ccaagggtaa ggatatggta
     4561 acttctcacg atgaaagtcc tttttttcag gagaggcaca ggaagcgata gttaaagcag
     4621 gctggtcttg aggcttggca aatgagcacc tttcatttaa gattgcgtga acacctaaga
     4681 aacagttctt gagcgatata tgactactgt tatgtcaaaa caaatcacac agttgctgtg
     4741 gtgactcatt aggctgagcc cttgagatac aatactaggg tgatgagggt tttaggaagg
     4801 agatcaattg tatttaatat ggtctggtct acacttgaga ttctaagtcc aggtctgaga
     4861 caaaggcata tgcccacgtc ctaaggaaag aaaattatct gagaacaata gaaaaaatat
     4921 ttgaagcact aatttagcct ggaaaaaata tttttcatac ccacctccac tctatcctta
     4981 atctgaattc agtttggcaa gagttgtttt atggcagcag aaatgtgagc tatgcttggc
     5041 tttcttatta gagatgggtt gtaggaaaaa ctaaggaaaa ctttttcaca agtgtgatga
     5101 agaaaaaaaa atagcaacaa agcaaacaaa aaatcctaaa cttgagaatt gacctataat
     5161 ggaacagata gtgggctctt atcatagtcc aatgaggaga aacttgttgt gcacagccac
     5221 tgggtgagac atcttcagtg gcaactcatg ggaggacaag agaaattctt caggcaatgc
     5281 aggatgagct gctttttact ttgtaaatgt ggtcttcaaa tcacatacac ccatttaagg
     5341 atgttatttg gagcaatcta gaagtataga atcaggcagg gaaaaccgtc ttctgtttta
     5401 ctatattata gctatatttt attgaacacc tatgtaccaa gcattacact aagcactttt
     5461 acatagctta tcacttaaat ctcaaaatat ctctgtgaag tattattaac tctaatgggt
     5521 gaagaagttg aggcttggag agttacataa tttgactgat gcaaaatggc tagcaagcga
     5581 tagagtaggg ttttcagtct aggagtatga atctagaacc gatgcttttt gccactttgc
     5641 tatcctgccc tttgatgatg tgggaccaat aacatatttt gagtagggta cacaaaagta
     5701 tgcaggattt gtacgctcta ttctgatgaa atagaatcta ggggttccat gaagaagatt
     5761 aaccaatgtc tccaaaagct aggtgataac atcagaggaa ggagcctccc cttgtaagga
     5821 gtcttctcag atggcaggga aaatgtgcct atgaccaaac accatatgaa tatgaaatca
     5881 tggaaaccaa tcatcctaag gagagagtaa ctaaacagct atcacacagg aatagaatgg
     5941 tagttaatgc tgacttcttt atattcaggt ttccccactt agattgttac atattatatg
     6001 atatggtaac acctgaatga ggcaatggag ggtgaataca tcaataaaca gagatgaaca
     6061 agtggtagag ctcagctgct ggctgtgcac agcagtagct atctttgtct catcaaacgt
     6121 ggccaagtga aacccctaac cttgttttat ccatagttgt cttgttgact atttatgttg
     6181 ggctggatgg acacctggga gtcatagctt aaacccaaaa cttaccacac acgtactaca
     6241 tgatcttggc tagaatattt aatctaagtt atacaaactg tgttgtatgg aatggatgtt
     6301 tgtcttatat tacaaatgga gaaatacact cagattatga atactacact tttaacatag
     6361 tactggcaca tactgtgtta ataataaagt gcttaacttt ctaaaggata aagctttctt
     6421 gtttggaaca tcttggttat caggaagagg gagttagttg tattaaagaa ccataacaac
     6481 ttattgggga gggggggtca tctataaggt aaccctaaga ttttccttgt agtaatttaa
     6541 tctattaact gaaccaaagt gaataggatc cagggtaaat ttagagaagg t
//
