LOCUS       NM_001005167             970 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 52 subfamily E member 6
            (OR52E6), mRNA.
ACCESSION   NM_001005167 XM_372366
VERSION     NM_001005167.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 970)
  AUTHORS   Shimada,M., Miyagawa,T., Kawashima,M., Tanaka,S., Honda,Y.,
            Honda,M. and Tokunaga,K.
  TITLE     An approach based on a genome-wide association study reveals
            candidate loci for narcolepsy
  JOURNAL   Hum Genet 128 (4), 433-441 (2010)
   PUBMED   20677014
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   2  (bases 1 to 970)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   3  (bases 1 to 970)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC131574.4.
            
            On May 17, 2019 this sequence version replaced NM_001005167.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000329322.5/ ENSP00000328878.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-970               AC131574.4         59111-60080
FEATURES             Location/Qualifiers
     source          1..970
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..970
                     /gene="OR52E6"
                     /gene_synonym="OR11-58"
                     /note="olfactory receptor family 52 subfamily E member 6"
                     /db_xref="GeneID:390078"
                     /db_xref="HGNC:HGNC:15215"
     exon            1..970
                     /gene="OR52E6"
                     /gene_synonym="OR11-58"
                     /inference="alignment:Splign:2.1.0"
     CDS             1..942
                     /gene="OR52E6"
                     /gene_synonym="OR11-58"
                     /note="olfactory receptor OR11-58"
                     /codon_start=1
                     /product="olfactory receptor 52E6"
                     /protein_id="NP_001005167.1"
                     /db_xref="CCDS:CCDS53597.1"
                     /db_xref="GeneID:390078"
                     /db_xref="HGNC:HGNC:15215"
                     /translation="MPIANDTQFHTSSFLLLGIPGLEDVHIWIGFPFFSVYLIALLGN
                     AAIFFVIQTEQSLHEPMYYCLAMLDSIDLSLSTATIPKMLGIFWFNIKEISFGGYLSQ
                     MFFIHFFTVMESIVLVAMAFDRYIAICKPLWYTMILTSKIISLIAGIAVLRSLYMVIP
                     LVFLLLRLPFCGHRIIPHTYCEHMGIARLACASIKVNIMFGLGSISLLLLDVLLIILS
                     HIRILYAVFCLPSWEARLKALNTCGSHIGVILAFSTPAFFSFFTHCFGHDIPQYIHIF
                     LANLYVVVPPTLNPVIYGVRTKHIRETVLRIFFKTDH"
ORIGIN      
        1 atgcctatag ctaacgacac ccagttccat acttcttcat tcctactgct gggtatccca
       61 gggctagaag atgtgcacat ctggattgga ttcccttttt tctctgtgta tcttattgca
      121 ctcctgggaa atgctgctat cttctttgtg atccaaactg agcagagtct ccatgagccc
      181 atgtactact gcctggccat gttggattcc attgacctga gcttgtctac ggccaccatt
      241 cccaaaatgc tgggcatctt ctggttcaat atcaaggaaa tatcttttgg aggctacctt
      301 tctcagatgt tcttcatcca tttcttcact gtcatggaga gcatcgtatt ggtggccatg
      361 gcctttgacc gctacattgc catttgcaaa cctctttggt acaccatgat cctcaccagc
      421 aaaatcatca gcctcattgc aggcattgct gtcctgagga gcttgtacat ggtcattcca
      481 ctggtgtttc tcctcttaag gttgcccttc tgtggacatc gtatcatccc tcatacttac
      541 tgtgagcaca tgggcattgc ccgtctggcc tgtgccagca tcaaagtcaa cattatgttt
      601 ggtcttggca gtatttctct cttgttattg gatgtgctcc ttattattct ctcccatatc
      661 aggatcctct atgctgtctt ctgcctgccc tcctgggaag ctcgactcaa agctctcaac
      721 acctgtggct ctcacattgg tgttatctta gccttttcta caccagcatt tttctctttc
      781 tttacacact gctttggcca tgatattccc caatatatcc acattttctt ggctaatcta
      841 tatgtggttg ttcctcccac cctcaatcct gtaatctatg gggtcagaac caaacatatt
      901 agggagacag tgctgaggat tttcttcaag acagatcact aaccagttgg agtttggagg
      961 gtctctctta
//
