LOCUS       NM_001005166            2244 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 52 subfamily E member 5
            (OR52E5), mRNA.
ACCESSION   NM_001005166 XM_372369
VERSION     NM_001005166.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2244)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131574.4 and AC025016.8.
            
            On Nov 19, 2020 this sequence version replaced NM_001005166.4.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA2148874, SAMEA2149178
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000610445.2/
                                                ENSP00000480583.1
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                AC131574.4         7738-7800           c
            64-145              AC131574.4         5295-5376           c
            146-521             AC131574.4         1-376               c
            522-2244            AC025016.8         2927-4649
FEATURES             Location/Qualifiers
     source          1..2244
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..2244
                     /gene="OR52E5"
                     /gene_synonym="OR11-56"
                     /note="olfactory receptor family 52 subfamily E member 5"
                     /db_xref="GeneID:390082"
                     /db_xref="HGNC:HGNC:15214"
     exon            1..63
                     /gene="OR52E5"
                     /gene_synonym="OR11-56"
                     /inference="alignment:Splign:2.1.0"
     exon            64..145
                     /gene="OR52E5"
                     /gene_synonym="OR11-56"
                     /inference="alignment:Splign:2.1.0"
     exon            146..2244
                     /gene="OR52E5"
                     /gene_synonym="OR11-56"
                     /inference="alignment:Splign:2.1.0"
     CDS             291..1274
                     /gene="OR52E5"
                     /gene_synonym="OR11-56"
                     /note="olfactory receptor OR11-56 pseudogene"
                     /codon_start=1
                     /product="olfactory receptor 52E5"
                     /protein_id="NP_001005166.3"
                     /db_xref="CCDS:CCDS91427.1"
                     /db_xref="GeneID:390082"
                     /db_xref="HGNC:HGNC:15214"
                     /translation="MLHTNNTQFHPSTFLVVGVPGLEDVHVWIGFPFFAVYLTALLGN
                     IIILFVIQTEQSLHQPMFYFLAMLAGTDLGLSTATIPKMLGIFWFNLGEIAFGACITQ
                     MYTIHICTGLESVVLTVTGIDRYIAICNPLRYSMILTNKVIAILGIVIIVRTLVFVTP
                     FTFLILRLPFCGVRIIPHTYCEHMGLAKLACASINVIYGLIAFSVGYIDISVIGFSYV
                     QILRAVFHLPAWDARPKALSTCGSHVCVMLAFYLPALFSFMTHRFGHNIPHYIHILLA
                     NLYVVFPPALNSVIYGVKTKQIREQVLRILNPKSFWHFDPKRIFHNNSVRQ"
ORIGIN      
        1 catacaggtt gcagtctggg gtatccggtc cttcacagac aatttctcag atgcggggca
       61 gagcaggatg atcatcttat tggcatttat ggttgacccc tgcggaagca ttacattgga
      121 ggaaacacaa taactgaaaa accaagtctc ttatgctata ttatggagtt aaagaatgga
      181 ttttctgttt ccccaagaaa tagacaccat gctgtgaaag aagttatggt ttctcactgg
      241 aagcaagaaa actcatgcaa gaaatgtgtc tgtagggaat ggccaccaat atgcttcata
      301 ccaacaatac acagtttcac ccttccacct tcctcgtagt gggggtccca gggctggaag
      361 atgtgcatgt atggattggc ttccccttct ttgcagtgta tctaacagcc cttctaggga
      421 acatcattat cctgtttgtg atacagactg aacagagcct ccaccaaccc atgttttact
      481 tcctagccat gttggccggc actgatctgg gcttgtctac agcaaccatc cccaagatgc
      541 tgggaatttt ctggtttaat cttggagaga ttgcatttgg tgcctgcatc acacagatgt
      601 ataccattca tatatgcact ggcctggagt ctgtggtact gacagtcacg ggcatagatc
      661 gctatattgc catctgcaac cccctgagat atagcatgat ccttaccaac aaggtaatag
      721 ccattctggg catagtcatc attgtcagga ctttggtatt tgtgactcca ttcacatttc
      781 tcatcctgag attgcctttc tgtggtgtcc ggattatccc tcatacctat tgtgaacaca
      841 tgggcttggc aaagttagct tgtgccagta ttaatgttat atatggattg attgccttct
      901 cagtgggata cattgacatt tctgtgattg gattttccta tgtccagatc ctccgagctg
      961 tcttccatct cccagcctgg gatgcccggc ctaaggcact cagcacatgt ggctctcacg
     1021 tctgtgttat gttggctttc tacctgccag ccctcttttc cttcatgaca caccgctttg
     1081 gccacaacat ccctcattac atccacattc ttctggccaa tctgtatgtg gtttttcccc
     1141 ctgctcttaa ctctgttatc tatggggtca aaacaaaaca gatacgagag caggtactta
     1201 ggatactcaa ccctaaaagc ttttggcatt ttgaccccaa gaggatcttc cacaacaatt
     1261 cagttagaca ataatgagat cataacaaaa taaacactgg aaacattttt tttactactt
     1321 ctcttgcatt cccacatgag ccaatagcat tatatcccct acaacgtctc atgatttcag
     1381 tacggtctgt tggaagttat agctcaaaga ttccaaaaca atctctctgt ttcacccatt
     1441 aaaagtgcaa aaagtactca cacttaagcc ccatgatact acaaaatgcc taaagagaaa
     1501 caaaggcttt gtaaaagtta ttgcccagta attgtcttga atagcctttc cacatgaaga
     1561 ttctctgtat ttacatatcc aaagctgaag ttcatgacga ttaaaatgat gtggtatttc
     1621 atcaaaacca ggcaggatac agtggcaaga gaaattaact aggagtcata agatctagat
     1681 ttaaatacag gttatggcct tacctaaaat tttgacctga gcatttcact tagactcttt
     1741 gagttcacaa taacaaattc atactgattt atagcatttt atgagcaggg atattgaagc
     1801 ttaaagtgaa tgttgtgaaa atctgtgcag cttgtaaaac attaaaagat ttggaaacaa
     1861 aatgagtgct tactaaacat aattatagtg taattgttat ttctaatgta tgtagatttc
     1921 atttactaat ccactctagt atacaatccc tggtttgagg tcagctctcc agatccagat
     1981 tatcccaacg catgggcctc ttcatggacc tctcagctct taccttcgtg aaagagactt
     2041 tcagtcagga gactataaag cttgaagagt taacaggttt ctgtcttggg cttaaggact
     2101 cagggaaatc ccatcctcca cagtctttgc tagagtgggt tttagggcag actgtaatag
     2161 tgtggctgct gaaataatat aaagtcattc ttaataaggt atagaagata aataggacaa
     2221 tttatttctt tgggtattct agga
//
