LOCUS       NM_001005163            1065 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 52 subfamily D member 1
            (OR52D1), mRNA.
ACCESSION   NM_001005163 XM_372359
VERSION     NM_001005163.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1065)
  AUTHORS   Shimada,M., Miyagawa,T., Kawashima,M., Tanaka,S., Honda,Y.,
            Honda,M. and Tokunaga,K.
  TITLE     An approach based on a genome-wide association study reveals
            candidate loci for narcolepsy
  JOURNAL   Hum Genet 128 (4), 433-441 (2010)
   PUBMED   20677014
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   2  (bases 1 to 1065)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   3  (bases 1 to 1065)
  AUTHORS   Bulger,M., Bender,M.A., van Doorninck,J.H., Wertman,B.,
            Farrell,C.M., Felsenfeld,G., Groudine,M. and Hardison,R.
  TITLE     Comparative structural and functional analysis of the olfactory
            receptor genes flanking the human and mouse beta-globin gene
            clusters
  JOURNAL   Proc Natl Acad Sci U S A 97 (26), 14560-14565 (2000)
   PUBMED   11121057
REFERENCE   4  (bases 1 to 1065)
  AUTHORS   Bulger,M., van Doorninck,J.H., Saitoh,N., Telling,A., Farrell,C.,
            Bender,M.A., Felsenfeld,G., Axel,R. and Groudine,M.
  TITLE     Conservation of sequence and structure flanking the mouse and human
            beta-globin loci: the beta-globin genes are embedded within an
            array of odorant receptor genes
  JOURNAL   Proc Natl Acad Sci U S A 96 (9), 5129-5134 (1999)
   PUBMED   10220430
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1999 Jul 6;96(14):8307. von
            Doorninck JH [corrected to van Doorninck JH]]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC087380.3.
            
            On Jan 21, 2010 this sequence version replaced NM_001005163.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC136928.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000322641.5/ ENSP00000326232.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1065              AC087380.3         134429-135493
FEATURES             Location/Qualifiers
     source          1..1065
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..1065
                     /gene="OR52D1"
                     /gene_synonym="OR11-43"
                     /note="olfactory receptor family 52 subfamily D member 1"
                     /db_xref="GeneID:390066"
                     /db_xref="HGNC:HGNC:15212"
     exon            1..1065
                     /gene="OR52D1"
                     /gene_synonym="OR11-43"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..979
                     /gene="OR52D1"
                     /gene_synonym="OR11-43"
                     /note="olfactory receptor OR11-43; HOR 5'Beta14; odorant
                     receptor HOR5'beta14"
                     /codon_start=1
                     /product="olfactory receptor 52D1"
                     /protein_id="NP_001005163.1"
                     /db_xref="CCDS:CCDS31384.1"
                     /db_xref="GeneID:390066"
                     /db_xref="HGNC:HGNC:15212"
                     /translation="MSDSNLSDNHLPDTFFLTGIPGLEAAHFWIAIPFCAMYLVALVG
                     NAALILVIAMDNALHAPMYLFLCLLSLTDLALSSTTVPKMLAILWLHAGEISFGGCLA
                     QMFCVHSIYALESSILLAMAFDRYVAICNPLRYTTILNHAVIGRIGFVGLFRSVAIVS
                     PFIFLLRRLPYCGHRVMTHTYCEHMGIARLACANITVNIVYGLTVALLAMGLDSILIA
                     ISYGFILHAVFHLPSHDAQHKALSTCGSHIGIILVFYIPAFFSFLTHRFGHHEVPKHV
                     HIFLANLYVLVPPVLNPILYGARTKEIRSRLLKLLHLGKTSI"
ORIGIN      
        1 agcccttcat ttgccaggaa gaatgtcaga ttccaacctc agtgataacc atcttccaga
       61 caccttcttc ttaacaggga tcccagggct ggaggctgcc cacttctgga ttgccatccc
      121 tttctgtgcc atgtatcttg tagcactggt tggaaatgct gccctcatcc tggtcattgc
      181 catggacaat gctcttcatg cacctatgta cctcttcctc tgccttctct cactcacaga
      241 cctggctctc agttctacca ctgtgcccaa gatgctggcc attttgtggc tccatgctgg
      301 tgagatttcc tttggtggat gcctggccca gatgttttgt gtccattcta tctatgctct
      361 ggagtcctca attctacttg ccatggcctt tgataggtat gtggctatct gtaacccatt
      421 aaggtacaca accattctca accatgctgt cataggcaga attggctttg ttgggctatt
      481 ccgtagtgtg gctattgtct cccccttcat cttcttgctg aggcgactcc cctactgtgg
      541 tcaccgtgtc atgacacaca catactgtga gcatatgggc attgcccgac tggcctgtgc
      601 caacatcact gtcaatattg tctatgggct aactgtggct ctgctggcca tgggactgga
      661 ttccattctc attgccattt cctatggctt tatcctccat gcagtctttc atcttccatc
      721 tcatgatgcc cagcacaaag ctctgagtac ctgtggctcc cacattggca tcatcctggt
      781 tttctacatc cctgccttct tctccttcct cacccaccgc tttggtcacc acgaagtccc
      841 caagcatgtg cacatctttc tggctaatct ctatgtgctg gtgcctcctg tactcaatcc
      901 tattctctat ggagctagaa ccaaggagat tcggagtcga cttctaaaac tgcttcacct
      961 ggggaagact tcaatatgaa tgctgagcag aagttggaga tttaaaaaaa agtgtaggat
     1021 ggctgtctag atacatttac atggacacac agtgatgatg tgaaa
//
