LOCUS       NM_001005160            3973 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 52 subfamily A member 5
            (OR52A5), mRNA.
ACCESSION   NM_001005160 XM_372352
VERSION     NM_001005160.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3973)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 3973)
  AUTHORS   Bulger,M., Bender,M.A., van Doorninck,J.H., Wertman,B.,
            Farrell,C.M., Felsenfeld,G., Groudine,M. and Hardison,R.
  TITLE     Comparative structural and functional analysis of the olfactory
            receptor genes flanking the human and mouse beta-globin gene
            clusters
  JOURNAL   Proc Natl Acad Sci U S A 97 (26), 14560-14565 (2000)
   PUBMED   11121057
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129505.8.
            
            On Jul 27, 2020 this sequence version replaced NM_001005160.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000307388.2/ ENSP00000303469.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                AC129505.8         11911-11956         c
            47-3973             AC129505.8         2376-6302           c
FEATURES             Location/Qualifiers
     source          1..3973
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..3973
                     /gene="OR52A5"
                     /gene_synonym="OR11-33"
                     /note="olfactory receptor family 52 subfamily A member 5"
                     /db_xref="GeneID:390054"
                     /db_xref="HGNC:HGNC:19580"
     exon            1..46
                     /gene="OR52A5"
                     /gene_synonym="OR11-33"
                     /inference="alignment:Splign:2.1.0"
     exon            47..3973
                     /gene="OR52A5"
                     /gene_synonym="OR11-33"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..1057
                     /gene="OR52A5"
                     /gene_synonym="OR11-33"
                     /note="olfactory receptor OR11-33; odorant receptor
                     HOR3'beta5"
                     /codon_start=1
                     /product="olfactory receptor 52A5"
                     /protein_id="NP_001005160.1"
                     /db_xref="CCDS:CCDS31373.1"
                     /db_xref="GeneID:390054"
                     /db_xref="HGNC:HGNC:19580"
                     /translation="MPTFNGSVFMPSAFILIGIPGLESVQCWIGIPFSAMYLIGVIGN
                     SLILVIIKYENSLHIPMYIFLAMLAATDIALNTCILPKMLGIFWFHLPEISFDACLFQ
                     MWLIHSFQAIESGILLAMALDRYVAICIPLRHATIFSQQFLTHIGLGVTLRAAILIIP
                     SLGLIKCCLKHYRTTVISHSYCEHMAIVKLATEDIRVNKIYGLFVAFAILGFDIIFIT
                     LSYVQIFITVFQLPQKEARFKAFNTCIAHICVFLQFYLLAFFSFFTHRFGSHIPPYIH
                     ILLSNLYLLVPPFLNPIVYGVKTKQIRDHIVKVFFFKKVT"
ORIGIN      
        1 gagttctcct ctatggcttc tacttataag tccattgata tccctggctc aacagagaat
       61 agaagatgaa acagcaaatc taccacttga ttctgatgaa caaatcatgc cgacattcaa
      121 tggctcagtc ttcatgccct ctgcgtttat actaattggg attcctggtc tggagtcagt
      181 gcagtgttgg attgggattc ctttctctgc catgtatctt attggtgtga ttggaaattc
      241 cctaatttta gttataatca aatatgaaaa cagcctccat atacccatgt acattttttt
      301 ggccatgttg gcagccacag acattgcact taacacctgc attcttccca aaatgttagg
      361 catcttctgg tttcatttgc cagagatttc ttttgatgcc tgtctttttc aaatgtggct
      421 tattcactca ttccaggcaa ttgaatcggg tatccttctg gcaatggccc tggatcgcta
      481 tgtggccatc tgtatcccct tgagacatgc caccatcttt tcccagcagt tcttaactca
      541 tattggactt ggggtgacac tcagggctgc cattcttata ataccttcct tagggctcat
      601 caaatgctgt ctgaaacact atcgaactac agtcatctct cactcttact gtgagcacat
      661 ggccatcgtg aagctggcta ctgaagatat ccgagtcaac aagatatatg gcctatttgt
      721 tgcctttgca atcctagggt ttgacataat atttataacc ttgtcctatg tccaaatttt
      781 tatcactgtc tttcagctgc cccagaagga ggcacgattc aaggccttta atacatgcat
      841 tgcccacatt tgtgtcttcc tacagttcta ccttcttgcc ttcttctctt tcttcacaca
      901 caggtttggt tcacacatac caccatatat tcatatcctc ttgtcaaatc tttacctgtt
      961 agtcccacct tttctcaacc ctattgtcta tggagtgaag accaagcaaa ttcgtgacca
     1021 tattgtgaaa gtgtttttct tcaaaaaagt aacttgatcg ttagtgactc ctatagagat
     1081 ttagggttgg ttctaagtaa aaacctaaat ataatgaaag tcacagatca atattctcaa
     1141 actactagct caacacatac ctgtaattct agctatgtct cactttttag tatttgcttt
     1201 gaatctatat tttgataaat ttggaatcat ttatctgtgt cttatttact ttatctgaaa
     1261 tacttatcaa tataaaaata atatgaaatc agtaataccg atatctacaa cataaaactt
     1321 atgtaatgca accaatgact ataaacacta aggaatttac acaggagaga atgcaaaaaa
     1381 aattgaaaaa tattaaacat attcacaaat atcattttca ggaaaataaa atcagtgatc
     1441 tgggcttaca tatcaaatat ccttctagaa ccacacaatt ttattgattt ttacctaact
     1501 tgagttttac tcaaatttgg aagtttaagt tctaaaattg aacatacaaa ttctgttacc
     1561 cactgaaagc atcttgagta cagaaactat cttatttacc ctttatcagg aaaacagtgg
     1621 acaatgcctg agaattctta gaatctaagt aaaaatgaca ttgaataatg aacagagtaa
     1681 acattttctt tgtgtcaatt aatggtattc aaaagccaca aatttggagg ctctaagtaa
     1741 tatgcaatct taccatacag aaaaccatgc tagagatttt attccaatat tatcagggta
     1801 aaagaaaggt gaagacttga aataatcatt atgcaaacct gaaataatat attagctaaa
     1861 cacagaactg gcatataaga aaccacctcc tgaataagga ctttagtcaa gacttagaac
     1921 caaacaaatt tttttttcct taagaatcaa gttgacagag tcatctgaat cactaatttt
     1981 gaaaagatgc atggtcaaag aaagaaataa tatggtaaaa cgttctgatg taaaaaatca
     2041 tatcattcaa gaggcagaca tagatacata caattttggg gaaaaatctt gtcaataatg
     2101 tagaaatgac tttgagtcat aattttttta ataaagttta tgtaaacatt atatttagaa
     2161 agaatcaaaa atacatgaca aaagataaaa caacatgtta gttgataggc agacatatta
     2221 aaaattgttg aattagataa gcaaaactta ataatgaaat aaccatttta attctggatt
     2281 agagcattaa atatttcagt ggttgtgcca ttaataacgc agaatgaata attaatgagg
     2341 agtcattctc ccaaaagaaa aaaaaatcat aaatatatga attctttcag aaaagttagt
     2401 atacatgaag gataaagaat gaagataata agtaagtgat actcctaaat aagaaaccaa
     2461 aacaaacaat atgatgataa ctacagatta atcatgagtg aatgaaaaaa ctgtatttca
     2521 aagtatctgg tataaaaatg caccaaatta tataaatgaa aatagacaaa acacccatat
     2581 tggaaaaaaa tcaacagaaa ataaaaattt caacataggt ctatcagaaa aaaacacatt
     2641 acatatccta aaagacatat ttttttttca ttctctggag tatgagggaa gacaaacaac
     2701 aaagatctta aaaatgcaca ttatctaatg gaaaaaaatt aaatgaaaaa tttgtgtcat
     2761 aattagactg tgggttggca tttcaagcca tttaaacctg taattaataa aaagaacaat
     2821 tacagtgcat aataatatta ctagtttctg aaacaatgtt gtccctgtcc agtgttctct
     2881 gctaaagaaa ccccagctga agcaatttcc acatggagta cagcacctgg tccagctgat
     2941 ttcagctagg tcccagtcag cacacagatc tgtttgactt cttggttgct ttttggtctt
     3001 ctttacaggt caaatttgtt ccatgctgaa gatctgggtt catattacct ttttttaagg
     3061 tataaaaaaa gacctggcct caaaatgagg ttgtacacgt agtttctgag agtctgctcc
     3121 attgctcttc aattgagggc tctggctaat tggatgcaga atccgagata aaggacagcc
     3181 acctacagca gctagagggc tgagatatga gtcagactga tatgccctga ctatgatgca
     3241 atgaacatct taaaaagaga aatttattcc aagaataaat tgtttgaggg ctcgaaggga
     3301 ttgccttaag ttaaagatgg ataaataggt atcctagcta ggaatcaaaa aggtctgagt
     3361 ttctccatta cccttccttt aacattctac atactcctgg gcatgttatt tcctcttctc
     3421 tacaatgggg ctaacaatac gagcctcaga gacttgtgag gaatatgtga gaaaaggctc
     3481 accaagcatg tagcacagat ccaggctaaa acacacctta aacatgtagg ccaaggtgta
     3541 catactctga gaattaagat gcagagaaaa atgatttcag gattaagtgc aaagagacgg
     3601 aaatgaatgg agcagagtgc cgggatagct gtgtggctga tgatcctcta gctggagcta
     3661 ggtcagtgtc tttgggcaga gctgtgtgta acattctcag aagcatgctg agacaacaga
     3721 ataccttggt gatctttatt caattgttta tttttactga gatggaattc acatgccata
     3781 atatttgcaa ttttaaagta tgcaatttga tgatttttag tgtattataa aggctgtgca
     3841 accatcatca ctacctaatt gaaaatactt tcgtcatcct aaaaaaaaat ctatatacat
     3901 tagtagtcac atcccattac ttctgctccc cccatctcca gtcttagcaa ctgctaatct
     3961 cttttctgtt tca
//
