LOCUS       NM_001004755            7300 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 51 subfamily L member 1
            (OR51L1), mRNA.
ACCESSION   NM_001004755 XM_061614
VERSION     NM_001004755.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7300)
  AUTHORS   Milton,J.N., Rooks,H., Drasar,E., McCabe,E.L., Baldwin,C.T.,
            Melista,E., Gordeuk,V.R., Nouraie,M., Kato,G.R., Minniti,C.,
            Taylor,J., Campbell,A., Luchtman-Jones,L., Rana,S., Castro,O.,
            Zhang,Y., Thein,S.L., Sebastiani,P., Gladwin,M.T. and
            Steinberg,M.H.
  CONSRTM   Walk-PHAAST Investigators
  TITLE     Genetic determinants of haemolysis in sickle cell anaemia
  JOURNAL   Br J Haematol 161 (2), 270-278 (2013)
   PUBMED   23406172
  REMARK    Erratum:[Br J Haematol. 2014 Aug;166(3):468. Kato, Gregory R
            [corrected to Kata, Gregory J]]
REFERENCE   2  (bases 1 to 7300)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC018375.8, AC113331.6 and KC877390.1.
            
            On Jul 27, 2020 this sequence version replaced NM_001004755.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641819.1/ ENSP00000493015.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-485               AC018375.8         41279-41763         c
            486-587             AC018375.8         39031-39132         c
            588-5444            AC018375.8         32934-37790         c
            5445-6379           AC113331.6         142534-143468       c
            6380-6896           KC877390.1         1-517               c
            6897-7300           AC113331.6         141613-142016       c
FEATURES             Location/Qualifiers
     source          1..7300
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..7300
                     /gene="OR51L1"
                     /gene_synonym="OR11-31"
                     /note="olfactory receptor family 51 subfamily L member 1"
                     /db_xref="GeneID:119682"
                     /db_xref="HGNC:HGNC:14759"
     exon            1..485
                     /gene="OR51L1"
                     /gene_synonym="OR11-31"
                     /inference="alignment:Splign:2.1.0"
     exon            486..587
                     /gene="OR51L1"
                     /gene_synonym="OR11-31"
                     /inference="alignment:Splign:2.1.0"
     exon            588..7300
                     /gene="OR51L1"
                     /gene_synonym="OR11-31"
                     /inference="alignment:Splign:2.1.0"
     CDS             747..1694
                     /gene="OR51L1"
                     /gene_synonym="OR11-31"
                     /note="olfactory receptor OR11-31"
                     /codon_start=1
                     /product="olfactory receptor 51L1"
                     /protein_id="NP_001004755.1"
                     /db_xref="CCDS:CCDS31369.1"
                     /db_xref="GeneID:119682"
                     /db_xref="HGNC:HGNC:14759"
                     /translation="MGDWNNSDAVEPIFILRGFPGLEYVHSWLSILFCLAYLVAFMGN
                     VTILSVIWIESSLHQPMYYFISILAVNDLGMSLSTLPTMLAVLWLDAPEIQASACYAQ
                     LFFIHTFTFLESSVLLAMAFDRFVAICHPLHYPTILTNSVIGKIGLACLLRSLGVVLP
                     TPLLLRHYHYCHGNALSHAFCLHQDVLRLSCTDARTNSIYGLCVVIATLGVDSIFILL
                     SYVLILNTVLDIASREEQLKALNTCVSHICVVLIFFVPVIGVSMVHRFGKHLSPIVHI
                     LMADIYLLLPPVLNPIVYSVRTKQIRLGILHKFVLRRRF"
ORIGIN      
        1 gtcgaaggtt ttcaaaacct gaggttcata gagacttaaa attgtagcat ctttaatcag
       61 tacaggtttg attttcaggt agagatggga agttttctca ggtgagagat aagcccgtaa
      121 gagcagcaac ttaaaccaca gacacacaaa gagaaattag aagaaagaaa cagccaatca
      181 aagggaccgg aaaaaataga ggattacatg ctgaaaagac acaaacttag ataaaaacaa
      241 aatataaaaa aatggcagca ggaaggaggc tagaaaagat agtaaagata atttgacaca
      301 taaaatgaga taaagagaga aaaagccaca gacataggaa cagaaagaaa atatgacttt
      361 aactatagtg aagaaaagtt tagtcagaga aagacaaaat ggaactgtgg atcatttgag
      421 aaatgggcta ctgattgcaa attaactagg catattgatt caattgcctt atatttaaat
      481 ttcaggtcag agactaaggg tccagaagga gggttgaggg aattactgag atgttgctac
      541 agagagatgt tgctgaagtc tatgaggccc agactctaag ggacaagggc cgacaagaga
      601 taccagcttc cttcctctgt gaggttagac gaaagatgta tttttgtcct cattccatta
      661 tttgtactca aaagagataa ctttgaggga tcaggaagga aaacacgaac cattcctcac
      721 tacttgctga attactcaaa gtcactatgg gagactggaa taacagtgat gctgtggagc
      781 ccatatttat cctgaggggt tttcctggac tggagtatgt tcattcttgg ctctccatcc
      841 tcttctgtct tgcatatttg gtagcattta tgggtaatgt taccatcctg tctgtcattt
      901 ggatagaatc ctctctccat cagcccatgt attactttat ttccatctta gcagtgaatg
      961 acctggggat gtccctgtct acacttccca ccatgcttgc tgtgttatgg ttggatgctc
     1021 cagagatcca ggcaagtgct tgctatgctc agctgttctt catccacaca ttcacattcc
     1081 tggagtcctc agtgttgctg gccatggcct ttgaccgttt tgttgctatc tgccatccac
     1141 tgcactaccc caccatcctc accaacagtg taattggcaa aattggtttg gcctgtttgc
     1201 tacgaagctt gggagttgta cttcccacac ctttgctact gagacactat cactactgcc
     1261 atggcaatgc cctctctcac gccttctgtt tgcaccagga tgttctaaga ttatcctgta
     1321 cagatgccag gaccaacagt atttatgggc tttgtgtagt cattgccaca ctaggtgtgg
     1381 attcaatctt catacttctt tcttatgttc tgattcttaa tactgtgctg gatattgcat
     1441 ctcgtgaaga gcagctaaag gcactcaaca catgtgtatc ccatatctgt gtggtgctta
     1501 tcttctttgt gccagttatt ggggtgtcaa tggtccatcg ctttgggaag catctgtctc
     1561 ccatagtcca catcctcatg gcagacatct accttcttct tcccccagtc cttaacccta
     1621 ttgtctatag tgtcagaaca aagcagattc gtctaggaat tctccacaag tttgtcctaa
     1681 ggaggaggtt ttaagtaacc tctgtcctcc aacttttcca ctgaaaatct catggaagct
     1741 gttttagtat atgaaaagta aaatatctgg gtgttgctca tctggttaaa atcctaattc
     1801 tttcacttct tatacatgta atttcagtta atctttaacc aatatgaaac tcaggatttt
     1861 tttggacaaa ttgtgacaac tatggcctta cgttgtcccc aggtcattac aagacttata
     1921 atagaaaatg tatgtgctaa gtcaagtttt ttgaaaacta tacaaaatta ttaatgttat
     1981 taagttgtca ttgttgttaa tgataacagt attttccttc ttaaatgtag ctgtgtttat
     2041 attgtttctc atgttaatta tctaaaactc agaaatcaat ctctatctct tttactagta
     2101 ctgctgcacg tattttgttg ttcatgctac aatgtcataa ctgtttatga aaaatttgag
     2161 tccttagggc aagtttggaa cttgagttcc tgacaggatt ttgacctgct gctgtggcca
     2221 tttgctatgt acaagttcta atctcatcac ttagtgatgt gtcctttctc tcattgctat
     2281 tctagatcta tcagcttcct caatttgcca gcaaatactg agttagatac atgggagtgt
     2341 taccaaatat agtttcagtt gatgccactt gcaaaatcat ataacaagaa tgaaggtggt
     2401 aagaagaatg ttactattcc agagcttagt gatgagaaag ggccagattt gtactgaaag
     2461 gagacacttc agcattctgg gcagaaagca gggttttaat aagagaaatt ttggtatgca
     2521 ggccatgcag aaggcacata gacttgtggg gtctataagg cttgctcacg gatgtttatc
     2581 ttgggtcatc tggtgggtca tccagtagtc tggccagtgg gggagaattt ggtagggtgc
     2641 ttggtttgtt ttaagacttg gtctatggaa cttctttttc tttctttttc ttttgagact
     2701 gagtcttgct ctgtcaccca ggtggaagtg caatggcgtg atctctgctc actgcaacct
     2761 tcgcctccta ggttcaagca attctcctgc cccagcctcc cgaatagctg ggatgacagg
     2821 tctgcgccac catccccagc taatttttgt atttttagta gatgcggggt ttcaccatgt
     2881 tgggcaggct ggactcgaac tcctgacctc aggtgatctg cccactttgg cctcccaaag
     2941 tgctgggatt acaggcgtga gctccctaga ccagctggcc tatggaactt ctaagaaaac
     3001 gtagagtaat ataaggaagt cgtgcttgca ggtggtttgg ccagtggaaa gaaaggaatg
     3061 taaaggtcgt aattgcatta ctaaagagca aaataagagg tgacggaaaa ggggaaaaat
     3121 tgtaaaatat acatatatat tttaaagaaa atggggtact cagttacagg aattgttgaa
     3181 gaaagcctga cagtacatgt ctaaccatct gggcaattgt gttgactctg ttcaatacta
     3241 taggacagga ttttgtgtct taatttgtga atgggttaag agttgtgcac aatctcaacc
     3301 ctcatctttt aataatactt ttacctcttg ttctacatgc ctgtgtggat ctgtagtatt
     3361 gtgtttttaa tcaatttatt tttgataacc cattactttt ttctttttca ctagaatgaa
     3421 ctacagatat gtttttatgg gtgatatttt attatttcat ataaattcac tttcttttca
     3481 gctgtatagc acactttttg aatatggggc catgtctatt accttatcac agcactatac
     3541 agctggtctt ccccaacaat catgagtact cattaaataa ttgaaataac tattatagtt
     3601 attgctgtta gtactgtgga tatataaaca gcaaaatgca taacgttaat gttaaataat
     3661 gaatgtttaa tagtgaagat acatagataa aaggttagta aaattaagtg taatcaatgg
     3721 tattattgga acaggtacct tttataatat tgatatatta ataagtggtc aatttcactt
     3781 gaggatttaa gaatcagtaa tcagagtagt tgacactttc actgtgcatt gtgagtcaaa
     3841 ttcattcttg accagttgaa cacagttgga aataaagtgg cgtaccaaag ctggcacata
     3901 agagacaatt gtgcatatct tgttctgctt ttgtgctctg taatgtcata taggttaatg
     3961 aaattggtta tgatggaagt atttaaacca cagaaattgg taaacattat atatcaggac
     4021 ttgaaatttt ttcttagaga ggaggtggtt aaacacttac caacacatca ctgggaaagg
     4081 tattctagaa agaggaggta acatgaagaa agcaaagagg ttagaaagag tatgtgttag
     4141 caacgttctt cagtctaact taaaacttac ccaaagcatt ttgcatttcc tcccacaaaa
     4201 aaagggctct gacatgggct atgatggaca aagatatgta gtttcagccc catttcaatg
     4261 aaagacttgt agccccagct gctggcagta agtccagtag aaagccttca attttttttt
     4321 ttttaccttt tcaggaattg cctcagctgg agaaatgagc cttgcctggg gtcatccact
     4381 gacacattca atgactaatg tagaaagttg gaaaggtctg gccccttcag cccagtgaat
     4441 ttcactgggc aattttatat ccaggactcc ccgtgatgtt ggacaaggct atcttcaggc
     4501 ctgattcaca ggtcaacttt tccctctgcc caatcctacc cactttcatt ccttttcatt
     4561 taagatgatt atcccaggga ttctcttatt aaacaaactg cacactaaat tttacctcaa
     4621 agtctgcttc ccagagaacc ctgaaatgag aagttctcag aaaacctgtg acgtaaaggt
     4681 gttaggggtg gctaatatcc aagtctcatg acatcaaata tattactggt ggaaggtatt
     4741 caagttacca gtggcaaatc catacgggtc tgcagcaacc tcaatttttg cctcctcaga
     4801 agaaagaaat tgactgaggg gcataaggca gagaaagaga tcaaggcaag tttcgagcag
     4861 gagtggaagt ttatttaaaa atgctttaga agaggaaaaa aggaaagtac gcttggaaga
     4921 gacccaaggg taaattgaag gacaagtgct gtgtttaacc ttaatcctag gaccttatag
     4981 tctggcgcct ttcccgtgat ccttccctta gagtgggcta cccacatgca cagtgccctc
     5041 cttaccctta ggaagtgagc atgcacagtg tgtttaggaa gttgtacacg tgcccatctg
     5101 aggctttctt ccctttctcg gtggtgtgcc ctcagaaggt catactcctt cattttgtct
     5161 cttaatgcac atgtctagaa agttacttcc ttttggcatc tgcattctat tagcagttta
     5221 gtgcaacagg tgtggaccat caggaaatgg cctctccctg gcgcaggctg ccaatttatc
     5281 acttttagag aggcaatgtg ataattgccc aaccattgcc taacattact agtgggtaag
     5341 ctagagccct ttcctgcccc actcatgcct aactacctgt aacatagaaa gataaaataa
     5401 aattctcaag gattcctttt tttcaggcag atgaaacagg atgagaattc aagagcaaat
     5461 atccatggtt tttaaatctc ttaagtttca agcggaagat caaacacagt gtgtaagcct
     5521 ggagaactaa aaataaccta taattcaagt tgacattgtg agatgtatgt atacaaccat
     5581 cttctacaat ctatgtactt tcttaatagt atgtctgatg actagaaatg ttcttaattt
     5641 taattaagtc caacttataa atttgctttt atgtttagtg cttttgtgta tttttaagga
     5701 gatatttgcc tattctgtca ttcaggatcc agtaagaaga caaaaatcac acagtaattt
     5761 gaatagagtt tataaataca aatacttatt aatttcataa ggaaatcaac tttaaagaag
     5821 gtaaagacaa cgctgagtaa taccctagag ctaagagaga atattgaaag aaaaaacaaa
     5881 cttggaaaat ggggaaggta ctccccaagc ccgaggttga aacttcattt gagaatgcat
     5941 agtcttagca tcctggatgc cagaaaaggt cattacattg catgtgttta gaaagacact
     6001 tctgtggggt ataggtgaac caaggctgag agactaagat tccttttcag gactgagtag
     6061 taggaagcac caggtgagct gaggcttgta ggcagggaac tatagttggc attggcaagc
     6121 aaatgataac ccccctttga agtacaggtg ggcagcaaat cacagtttgg actgacaagc
     6181 tggaaacacc cctccagggt ccaaataggt tatttgggaa gccagtccct agagtaactg
     6241 caagactcag taagagtcta gccatatggg tattgttgaa atttgatagg atgagtatta
     6301 ctaaatattt ctcattacac gcctctggta gaagagagag aataatcaaa gagaagtaca
     6361 cacgaacttc tcttacaagt gtccctgcgg caccctctgc tggccaagtt taacatcatg
     6421 aatctgtgaa ggaaaaaatg tccattgagc ccagttccat tgttgcagag taagcaatga
     6481 agtctatatt tgaaactggg acaataaata aataactgac acatttgctg atattatcaa
     6541 tgatgtcctt ctgtgtaatt tttgaaagtt gtaaggcttt ccttttgata tttctaaata
     6601 caacacatgt agaatttatt tttatgaatg atgaggtaag gtcaaggcat attttttgat
     6661 atgaatacat agttcagtca gaactatgta aaagaaaata aaaattgaag gaccccccaa
     6721 acttgtgcag aagtaaagac taagtcctga agctgaatca ttgcaacact ctcttccaca
     6781 tgaataactg ttactaacat tatatatcag ccagactgga aaggtaaatg gcctcaggca
     6841 tctgggaagg gctacccaca gatcattcat aagtaaattc tttgcttgcc tcccataaac
     6901 aaggacacgc tagttgtaaa tttaggtcca caatccaggt ctagctccta aaactccaca
     6961 ccgattatgt cacttacaag tttatcttcc caggtgcaga aaagtcaaga ttcattttct
     7021 tcacctaccc agagacgact acatgattga gtcttccttt actccctttc tcgcttcaga
     7081 cattcacctt atcttacgta aaatgtagat ttactgaaca ctaactgaag tctcaggaat
     7141 gtaactattt cccctactgc ccaacctaca tgcctccccc ttcccccttt taaggaaatg
     7201 gataaataca caatgtcctg aaaacctttg tggaaatagc cacagatgtg tcggtggctt
     7261 ttgtttttcc cagaagtgcc ctaaacctgg cttaataaac
//
