LOCUS       NM_001004752             960 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 51 subfamily F member 1
            (OR51F1), mRNA.
ACCESSION   NM_001004752 XM_171424
VERSION     NM_001004752.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Band,G., Le,Q.S., Jostins,L., Pirinen,M., Kivinen,K., Jallow,M.,
            Sisay-Joof,F., Bojang,K., Pinder,M., Sirugo,G., Conway,D.J.,
            Nyirongo,V., Kachala,D., Molyneux,M., Taylor,T., Ndila,C.,
            Peshu,N., Marsh,K., Williams,T.N., Alcock,D., Andrews,R.,
            Edkins,S., Gray,E., Hubbart,C., Jeffreys,A., Rowlands,K.,
            Schuldt,K., Clark,T.G., Small,K.S., Teo,Y.Y., Kwiatkowski,D.P.,
            Rockett,K.A., Barrett,J.C. and Spencer,C.C.
  CONSRTM   Malaria Genomic Epidemiology Network
  TITLE     Imputation-based meta-analysis of severe malaria in three African
            populations
  JOURNAL   PLoS Genet 9 (5), e1003509 (2013)
   PUBMED   23717212
  REMARK    Erratum:[PLoS Genet. 2013 Jun;9(6).
            doi:10.1371/annotation/adc2beaf-4bee-4e22-925b-6788d62fe029.
            Malaria Genomic Epidemiological Network [corrected to Malaria
            Genomic Epidemiology Network]]
REFERENCE   2  (bases 1 to 960)
  AUTHORS   Olender,T., Waszak,S.M., Viavant,M., Khen,M., Ben-Asher,E.,
            Reyes,A., Nativ,N., Wysocki,C.J., Ge,D. and Lancet,D.
  TITLE     Personal receptor repertoires: olfaction as a model
  JOURNAL   BMC Genomics 13, 414 (2012)
   PUBMED   22908908
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 960)
  AUTHORS   Menashe,I., Aloni,R. and Lancet,D.
  TITLE     A probabilistic classifier for olfactory receptor pseudogenes
  JOURNAL   BMC Bioinformatics 7, 393 (2006)
   PUBMED   16939646
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 960)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   5  (bases 1 to 960)
  AUTHORS   Gilad,Y. and Lancet,D.
  TITLE     Population differences in the human functional olfactory repertoire
  JOURNAL   Mol Biol Evol 20 (3), 307-314 (2003)
   PUBMED   12644552
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC103710.2.
            
            On Jan 3, 2019 this sequence version replaced NM_001004752.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jun 2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000624103.2/ ENSP00000485387.2
            polymorphic pseudogene :: PMID: 22908908
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-960               AC103710.2         78676-79635
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..960
                     /gene="OR51F1"
                     /gene_synonym="OR11-21; OR51F1P"
                     /note="olfactory receptor family 51 subfamily F member 1"
                     /db_xref="GeneID:256892"
                     /db_xref="HGNC:HGNC:15196"
     CDS             1..960
                     /gene="OR51F1"
                     /gene_synonym="OR11-21; OR51F1P"
                     /note="olfactory receptor, family 51, subfamily F, member
                     1 pseudogene; olfactory receptor OR11-21 pseudogene"
                     /codon_start=1
                     /product="olfactory receptor 51F1"
                     /protein_id="NP_001004752.2"
                     /db_xref="CCDS:CCDS31359.1"
                     /db_xref="GeneID:256892"
                     /db_xref="HGNC:HGNC:15196"
                     /translation="MLQNQDTMEILSNSTSKFPTFLLTGIPGLESAHVWISIPFCCFY
                     AIALSGNSVILFVIITQQSLHEPMYYFLFRLSATDLGLTVSSLSTTLGILWFEAREIS
                     LYSCIVQMFFLHGFTFMESGVLVATAFDRYVAICDPLRYTTILTNSRIIQMGLLMITR
                     AIVLILPLLLLLKPLYFCRMNALSHSYCYHPDVIQLACSDIRANSICGLIDLILTTGI
                     DTPCIVLSYILIIHSVLRIASPEEWHKVFSTCVSHVGAVAFFYIHMLSLSLVYRYGRS
                     APRVVHSVMANVYLLLPPVLNPIIDSVKTKQIRKAMLSLLLTK"
     exon            1..960
                     /gene="OR51F1"
                     /gene_synonym="OR11-21; OR51F1P"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgctgcaaa accaggacac catggaaatc ctaagcaact caacatctaa atttccaacc
       61 ttcttgttga ccggcattcc tggcctagag tctgcccatg tctggatctc cattcctttc
      121 tgttgttttt atgccattgc cctctctggg aacagcgtga tcctgtttgt catcattacc
      181 cagcagagtc tccatgaacc catgtattat ttcctcttca ggctatcagc cactgatctg
      241 ggcttgactg tttcttcatt gtcaacaaca ttaggtatcc tctggtttga ggcacgtgaa
      301 atcagtctat atagctgcat tgtccagatg ttttttcttc atggattcac ttttatggaa
      361 tctggagtgc tggtggctac agcctttgac cgttatgtgg ccatctgtga ccctctgagg
      421 tacactacca ttctcactaa ttccagaatc attcaaatgg gtcttctgat gattacacgt
      481 gctatagtac taatattgcc actacttttg ctccttaagc ctctctattt ctgtagaatg
      541 aatgcccttt ctcactccta ttgttaccat ccagatgtga ttcaattagc atgttcagac
      601 attcgggcaa atagcatctg tggattaatt gatctcatcc tgaccactgg aatagataca
      661 ccatgcattg tcctgtcata tatcttaatt attcactctg tcctcagaat tgcctcccct
      721 gaagaatggc acaaggtctt cagcacctgt gtctcccatg tgggagcagt tgctttcttc
      781 tacatccaca tgctgagcct gtccttggtg tatcgctatg gtcggtcagc ccccagagta
      841 gtccattcag tgatggctaa tgtatacctg cttttacccc ctgtgctcaa ccccatcatc
      901 gacagtgtaa aaacaaaaca aatccgcaag gctatgctca gtctgctgct tacaaaatga
//
