LOCUS       NM_001004750             939 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 51 subfamily B member 6
            (OR51B6), mRNA.
ACCESSION   NM_001004750 XM_372353
VERSION     NM_001004750.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 939)
  AUTHORS   Solovieff,N., Milton,J.N., Hartley,S.W., Sherva,R., Sebastiani,P.,
            Dworkis,D.A., Klings,E.S., Farrer,L.A., Garrett,M.E.,
            Ashley-Koch,A., Telen,M.J., Fucharoen,S., Ha,S.Y., Li,C.K.,
            Chui,D.H., Baldwin,C.T. and Steinberg,M.H.
  TITLE     Fetal hemoglobin in sickle cell anemia: genome-wide association
            studies suggest a regulatory region in the 5' olfactory receptor
            gene cluster
  JOURNAL   Blood 115 (9), 1815-1822 (2010)
   PUBMED   20018918
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   2  (bases 1 to 939)
  AUTHORS   Bulger,M., Bender,M.A., van Doorninck,J.H., Wertman,B.,
            Farrell,C.M., Felsenfeld,G., Groudine,M. and Hardison,R.
  TITLE     Comparative structural and functional analysis of the olfactory
            receptor genes flanking the human and mouse beta-globin gene
            clusters
  JOURNAL   Proc Natl Acad Sci U S A 97 (26), 14560-14565 (2000)
   PUBMED   11121057
REFERENCE   3  (bases 1 to 939)
  AUTHORS   Bulger,M., van Doorninck,J.H., Saitoh,N., Telling,A., Farrell,C.,
            Bender,M.A., Felsenfeld,G., Axel,R. and Groudine,M.
  TITLE     Conservation of sequence and structure flanking the mouse and human
            beta-globin loci: the beta-globin genes are embedded within an
            array of odorant receptor genes
  JOURNAL   Proc Natl Acad Sci U S A 96 (9), 5129-5134 (1999)
   PUBMED   10220430
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1999 Jul 6;96(14):8307. von
            Doorninck JH [corrected to van Doorninck JH]]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC104389.8.
            
            On Sep 22, 2004 this sequence version replaced XM_372353.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000380219.1/ ENSP00000369568.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-939               AC104389.8         153848-154786
FEATURES             Location/Qualifiers
     source          1..939
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..939
                     /gene="OR51B6"
                     /gene_synonym="HOR5'Beta6"
                     /note="olfactory receptor family 51 subfamily B member 6"
                     /db_xref="GeneID:390058"
                     /db_xref="HGNC:HGNC:19600"
     CDS             1..939
                     /gene="OR51B6"
                     /gene_synonym="HOR5'Beta6"
                     /note="olfactory receptor 51B5; odorant receptor
                     HOR5'beta6"
                     /codon_start=1
                     /product="olfactory receptor 51B6"
                     /protein_id="NP_001004750.1"
                     /db_xref="CCDS:CCDS31379.1"
                     /db_xref="GeneID:390058"
                     /db_xref="HGNC:HGNC:19600"
                     /translation="MGLNKSASTFQLTGFPGMEKAHHWIFIPLLAAYISILLGNGTLL
                     FLIRNDHNLHEPMYYFLAMLAATDLGVTLTTMPTVLGVLWLDHREIGHGACFSQAYFI
                     HTLSVMESGVLLAMAYDCFITIRSPLRYTSILTNTQVMKIGVRVLTRAGLSIMPIVVR
                     LHWFPYCRSHVLSHAFCLHQDVIKLACADITFNRLYPVVVLFAMVLLDFLIIFFSYIL
                     ILKTVMGIGSGGERAKALNTCVSHICCILVFYVTVVCLTFIHRFGKHVPHVVHITMSY
                     IHFLFPPFMNPFIYSIKTKQIQSGILRLFSLPHSRA"
     exon            1..939
                     /gene="OR51B6"
                     /gene_synonym="HOR5'Beta6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggggctca ataagtctgc ttccaccttc cagcttactg gcttcccagg catggagaag
       61 gcacatcact ggatattcat cccattattg gcagcctaca tctccatact tcttggcaat
      121 ggcactcttc tctttctcat caggaatgat cataacctcc atgagcccat gtactatttc
      181 ttagctatgt tggcagctac agacctcgga gtgacattga ccacaatgcc cacagtgcta
      241 ggtgttctgt ggttagatca cagggagatt ggccatggag cctgcttctc tcaggcctat
      301 tttatccata ctctttctgt catggagtca ggtgtcttgc ttgccatggc ttatgactgt
      361 ttcattacca tccgcagccc cttaagatat acctctatcc tgaccaacac ccaggtaatg
      421 aagattggtg tgcgggtatt gacaagggct ggtctgtcca ttatgccaat agttgttcgc
      481 ctacactggt ttccctactg tcgatcccat gtactctccc atgctttctg tctacaccaa
      541 gatgtcatca agctagcctg tgctgacatc accttcaacc gtctctatcc agttgtagtt
      601 ttatttgcaa tggtcttgtt ggactttctc atcatctttt tctcctacat tttgattctc
      661 aagactgtca tgggcattgg ttctggagga gaaagggcca aggccctcaa cacatgtgtc
      721 tctcatatct gctgcatcct ggtcttctat gtcactgtag tttgtctgac atttattcat
      781 aggtttggaa agcatgttcc tcatgtcgtt cacatcacaa tgagctacat ccacttcctt
      841 ttcccacctt ttatgaaccc atttatctat agcattaaaa ctaagcagat tcagagtggc
      901 atacttcgtt tattctctct gcctcactct agagcatga
//
