LOCUS       NM_001004727             912 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily X member 2
            (OR4X2), mRNA.
ACCESSION   NM_001004727 XM_061666
VERSION     NM_001004727.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 912)
  AUTHORS   Olender,T., Waszak,S.M., Viavant,M., Khen,M., Ben-Asher,E.,
            Reyes,A., Nativ,N., Wysocki,C.J., Ge,D. and Lancet,D.
  TITLE     Personal receptor repertoires: olfaction as a model
  JOURNAL   BMC Genomics 13, 414 (2012)
   PUBMED   22908908
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 912)
  AUTHORS   Menashe,I., Aloni,R. and Lancet,D.
  TITLE     A probabilistic classifier for olfactory receptor pseudogenes
  JOURNAL   BMC Bioinformatics 7, 393 (2006)
   PUBMED   16939646
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 912)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   4  (bases 1 to 912)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB065847.1.
            
            On Sep 19, 2004 this sequence version replaced XM_061666.4.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jun 2015].
            
            Sequence Note: This gene is a segregating pseudogene. This RefSeq
            represents the protein encoded by the reference genome allele,
            which is predicted to be non-functional as an olfactory receptor
            according to the Classifier for Olfactory Receptor Pseudogenes.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000624868.2/ ENSP00000485431.1
            polymorphic pseudogene :: PMID: 22908908
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..912
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p11.2"
     gene            1..912
                     /gene="OR4X2"
                     /gene_synonym="OR11-105"
                     /note="olfactory receptor family 4 subfamily X member 2"
                     /db_xref="GeneID:119764"
                     /db_xref="HGNC:HGNC:15184"
     CDS             1..912
                     /gene="OR4X2"
                     /gene_synonym="OR11-105"
                     /note="olfactory receptor OR11-105"
                     /codon_start=1
                     /product="olfactory receptor 4X2"
                     /protein_id="NP_001004727.1"
                     /db_xref="GeneID:119764"
                     /db_xref="HGNC:HGNC:15184"
                     /translation="MTEFIFLVLSPNQEVQRVCFVIFLFLYTAIVLGNFLIVLTVMTS
                     RSLGSPMYFFLSYLSFMEICYSSATAPKLISDLLAERKVISWWGCMAQLFFLHFFGGT
                     EIFLLTVMAYDHYVAICKPLSYTTIMNWQVCTVLVGIAWVGGFMHSFAQILLIFHLLF
                     CGPNVINHYFCDLVPLLKLACSDTFLIGLLIVANGGTLSVISFGVLLASYMVILLHLR
                     TWSSEGWCKALSTCGSHFAVVILFFGPCVFNSLRPSTTLPIDKMVAVFYTVITAILNP
                     VIYSLRNAEMRKAMKRLWIRTLRLNEK"
     exon            1..912
                     /gene="OR4X2"
                     /gene_synonym="OR11-105"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgactgaat tcatttttct ggtactttct cccaaccagg aggtgcagag ggtttgcttt
       61 gtgatatttc tgttcttgta cacagcaatt gtgctgggga atttcctcat tgtgctcact
      121 gtcatgacca gcagaagcct tggttccccc atgtacttct tcctcagcta cctctccttc
      181 atggagatct gctactcctc cgctacagcc cccaaactca tctcagatct gctggctgaa
      241 aggaaagtca tatcttggtg gggctgcatg gcacagcttt tcttcttgca cttctttggt
      301 ggcactgaga ttttcctgct cactgtgatg gcctatgacc actatgtggc catctgcaag
      361 cccctcagct acaccaccat catgaactgg caggtgtgta ctgtccttgt aggaatagca
      421 tgggtgggag gcttcatgca ttcctttgca caaatccttc tcatcttcca cctgctcttc
      481 tgtggcccca atgtgatcaa tcactatttc tgtgacctag ttccccttct caaacttgcc
      541 tgctctgaca ccttcctcat tggtctgctg attgttgcca atggaggcac cctgtctgtg
      601 atcagttttg gggtcctctt agcatcctat atggtcatct tgctccatct gagaacctgg
      661 agctctgaag ggtggtgcaa agccctctcc acctgtgggt cccatttcgc tgtggttatc
      721 ttgttctttg ggccctgcgt cttcaactct ctgaggcctt ctaccactct gcccatagac
      781 aagatggtgg ctgtgttcta cacagtgata accgcgatcc tgaaccctgt catctactct
      841 ctgagaaatg ctgaaatgag gaaggccatg aagaggctgt ggattaggac attgagacta
      901 aatgagaaat ag
//
