LOCUS       NM_001004059            2211 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily S member 2
            (OR4S2), mRNA.
ACCESSION   NM_001004059 XM_166871
VERSION     NM_001004059.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2211)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 2211)
  AUTHORS   Gilad,Y. and Lancet,D.
  TITLE     Population differences in the human functional olfactory repertoire
  JOURNAL   Mol Biol Evol 20 (3), 307-314 (2003)
   PUBMED   12644552
REFERENCE   3  (bases 1 to 2211)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP006437.2.
            
            On Aug 5, 2020 this sequence version replaced NM_001004059.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641692.1/ ENSP00000493389.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-224               AP006437.2         74941-75164
            225-2211            AP006437.2         77482-79468
FEATURES             Location/Qualifiers
     source          1..2211
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q11"
     gene            1..2211
                     /gene="OR4S2"
                     /gene_synonym="OR11-137; OR4S2P; OST725"
                     /note="olfactory receptor family 4 subfamily S member 2"
                     /db_xref="GeneID:219431"
                     /db_xref="HGNC:HGNC:15183"
     exon            1..224
                     /gene="OR4S2"
                     /gene_synonym="OR11-137; OR4S2P; OST725"
                     /inference="alignment:Splign:2.1.0"
     exon            225..2211
                     /gene="OR4S2"
                     /gene_synonym="OR11-137; OR4S2P; OST725"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..1196
                     /gene="OR4S2"
                     /gene_synonym="OR11-137; OR4S2P; OST725"
                     /note="olfactory receptor OR11-137; olfactory receptor,
                     family 4, subfamily S, member 2 pseudogene"
                     /codon_start=1
                     /product="olfactory receptor 4S2"
                     /protein_id="NP_001004059.2"
                     /db_xref="CCDS:CCDS31505.1"
                     /db_xref="GeneID:219431"
                     /db_xref="HGNC:HGNC:15183"
                     /translation="MEKINNVTEFIFWGLSQSPEIEKVCFVVFSFFYIIILLGNLLIM
                     LTVCLSNLFKSPMYFFLSFLSFVDICYSSVTAPKMIVDLLAKDKTISYVGCMLQLFGV
                     HFFGCTEIFILTVMAYDRYVAICKPLHYMTIMNRETCNKMLLGTWVGGFLHSIIQVAL
                     VVQLPFCGPNEIDHYFCDVHPVLKLACTETYIVGVVVTANSGTIALGSFVILLISYSI
                     ILVSLRKQSAEGRRKALSTCGSHIAMVVIFFGPCTFMYMRPDTTFSEDKMVAVFYTII
                     TPMLNPLIYTLRNAEVKNAMKKLWGRNVFLEAKGK"
ORIGIN      
        1 caaagaccct gtgaaatggc aggtatcatt aggtgagaaa accaggaaca acaaagactc
       61 atttctacca gcctttcagt ttggggggtc aggtattttc cggtactaat tattcacaaa
      121 ggaattccct aggcatcact gttactttac cttgggaagc tgcacccaaa ttaactcaag
      181 aagagataga aacataaagt gaactcaagc tctggaaaat actggtaatt taattgtctc
      241 ctaagaactt gacccattcc atggaaaaaa taaacaacgt aactgaattc attttctggg
      301 gtctttctca gagcccagag attgagaaag tttgttttgt ggtgttttct ttcttctaca
      361 taatcattct tctgggaaat ctcctcatca tgctgacagt ttgcctgagc aacctgttta
      421 agtcacccat gtatttcttt ctcagcttct tgtcttttgt ggacatttgt tactcttcag
      481 tcacagctcc caagatgatt gttgacctgt tagcaaagga caaaaccatc tcctatgtgg
      541 ggtgcatgtt gcaactgttt ggagtacatt tctttggttg cactgagatc ttcatcctta
      601 ctgtaatggc ctatgatcgt tatgtggcta tctgtaaacc cctacattat atgaccatca
      661 tgaaccggga gacatgcaat aaaatgttat tagggacgtg ggtaggtggg ttcttacact
      721 ccattatcca agtggctctg gtagtccaac tacccttttg tggacccaat gagatagatc
      781 actacttttg tgatgttcac cctgtgttga aacttgcctg cacagaaaca tacattgttg
      841 gtgttgttgt gacagccaac agtggtacca ttgctctggg gagttttgtt atcttgctaa
      901 tctcctacag catcatccta gtttccctga gaaagcagtc agcagaaggc aggcgcaaag
      961 ccctctccac ctgtggctcc cacattgcca tggtcgttat ctttttcggc ccctgtactt
     1021 ttatgtacat gcgccctgat acgacctttt cagaggataa gatggtggct gtattttaca
     1081 ccattatcac tcccatgtta aatcctctga tttatacact gagaaatgca gaagtaaaga
     1141 atgcaatgaa gaaactgtgg ggcagaaatg ttttcttgga ggctaaaggg aaatagttgg
     1201 acttaataat ttaagctaga tgaccttaaa atttctcagc cttggttaac tcatctgtgc
     1261 aatcaagaca ataacaacct catgggattt ggagtggaaa aatgagacaa taacacattc
     1321 aaaagagtaa ggtattattt ttcattatta tagcattttt atactatttc ataattagat
     1381 aacttcctga aatatctatg acacagaaat attattaaac ttagaatcac aaaagtgcag
     1441 aagagcaatt cctcttggct ttcctttgag gacagatttc tattacccta ccttgctatt
     1501 cactggtttt atcatcatcc ctgaaagcag aaactcacca tatgtataaa gtggaggaaa
     1561 taaattttaa aaaatttaga atttccaaaa gtgtgggaag tgttttcata tttttgggct
     1621 taaattgtga ggtttcgggc agtacagtat cactcatata tttccttcta aataaacaat
     1681 cctctaccct gctgcctagg ctatgtatag agtagtgggg aattgataag gttgtaatgt
     1741 gtgctgactg ctgacatctg gggagcagca agaggaaagg gcctcatagt tcacactgta
     1801 gatttcactt atccttgtgc atgcgtgttt catcactgtc ctccacatta atactgggaa
     1861 ttatttagct cagtctttca aaagaataaa cctccaatct tttgtgaagt aatatagagg
     1921 aattcttacc tgtctgtgta gaaaatggcc tgtggaaata aaataatttt catgtaatac
     1981 aatgtatgtt tcactcctac attctgtaga atcgtatgct acaagcattt agcatctcag
     2041 gagttttgca agtgaactaa cttgctagtt ttctctgtcc ttgctcagat ggctataact
     2101 tcccccacaa tgctaagtta actacttagt aacactgttc tctatttctc aaaaaatgtg
     2161 tgaaaatctt tcaccagctg gtatttcctg tttgcttttt tgtcattgtg g
//
