LOCUS       NM_001004725             930 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily S member 1
            (OR4S1), mRNA.
ACCESSION   NM_001004725 XM_171490
VERSION     NM_001004725.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Manning,A.K., Hivert,M.F., Scott,R.A., Grimsby,J.L.,
            Bouatia-Naji,N., Chen,H., Rybin,D., Liu,C.T., Bielak,L.F.,
            Prokopenko,I., Amin,N., Barnes,D., Cadby,G., Hottenga,J.J.,
            Ingelsson,E., Jackson,A.U., Johnson,T., Kanoni,S., Ladenvall,C.,
            Lagou,V., Lahti,J., Lecoeur,C., Liu,Y., Martinez-Larrad,M.T.,
            Montasser,M.E., Navarro,P., Perry,J.R., Rasmussen-Torvik,L.J.,
            Salo,P., Sattar,N., Shungin,D., Strawbridge,R.J., Tanaka,T., van
            Duijn,C.M., An,P., de Andrade,M., Andrews,J.S., Aspelund,T.,
            Atalay,M., Aulchenko,Y., Balkau,B., Bandinelli,S., Beckmann,J.S.,
            Beilby,J.P., Bellis,C., Bergman,R.N., Blangero,J., Boban,M.,
            Boehnke,M., Boerwinkle,E., Bonnycastle,L.L., Boomsma,D.I.,
            Borecki,I.B., Bottcher,Y., Bouchard,C., Brunner,E., Budimir,D.,
            Campbell,H., Carlson,O., Chines,P.S., Clarke,R., Collins,F.S.,
            Corbaton-Anchuelo,A., Couper,D., de Faire,U., Dedoussis,G.V.,
            Deloukas,P., Dimitriou,M., Egan,J.M., Eiriksdottir,G., Erdos,M.R.,
            Eriksson,J.G., Eury,E., Ferrucci,L., Ford,I., Forouhi,N.G.,
            Fox,C.S., Franzosi,M.G., Franks,P.W., Frayling,T.M., Froguel,P.,
            Galan,P., de Geus,E., Gigante,B., Glazer,N.L., Goel,A., Groop,L.,
            Gudnason,V., Hallmans,G., Hamsten,A., Hansson,O., Harris,T.B.,
            Hayward,C., Heath,S., Hercberg,S., Hicks,A.A., Hingorani,A.,
            Hofman,A., Hui,J., Hung,J., Jarvelin,M.R., Jhun,M.A., Johnson,P.C.,
            Jukema,J.W., Jula,A., Kao,W.H., Kaprio,J., Kardia,S.L.,
            Keinanen-Kiukaanniemi,S., Kivimaki,M., Kolcic,I., Kovacs,P.,
            Kumari,M., Kuusisto,J., Kyvik,K.O., Laakso,M., Lakka,T.,
            Lannfelt,L., Lathrop,G.M., Launer,L.J., Leander,K., Li,G., Lind,L.,
            Lindstrom,J., Lobbens,S., Loos,R.J., Luan,J., Lyssenko,V., Magi,R.,
            Magnusson,P.K., Marmot,M., Meneton,P., Mohlke,K.L., Mooser,V.,
            Morken,M.A., Miljkovic,I., Narisu,N., O'Connell,J., Ong,K.K.,
            Oostra,B.A., Palmer,L.J., Palotie,A., Pankow,J.S., Peden,J.F.,
            Pedersen,N.L., Pehlic,M., Peltonen,L., Penninx,B., Pericic,M.,
            Perola,M., Perusse,L., Peyser,P.A., Polasek,O., Pramstaller,P.P.,
            Province,M.A., Raikkonen,K., Rauramaa,R., Rehnberg,E., Rice,K.,
            Rotter,J.I., Rudan,I., Ruokonen,A., Saaristo,T., Sabater-Lleal,M.,
            Salomaa,V., Savage,D.B., Saxena,R., Schwarz,P., Seedorf,U.,
            Sennblad,B., Serrano-Rios,M., Shuldiner,A.R., Sijbrands,E.J.,
            Siscovick,D.S., Smit,J.H., Small,K.S., Smith,N.L., Smith,A.V.,
            Stancakova,A., Stirrups,K., Stumvoll,M., Sun,Y.V., Swift,A.J.,
            Tonjes,A., Tuomilehto,J., Trompet,S., Uitterlinden,A.G.,
            Uusitupa,M., Vikstrom,M., Vitart,V., Vohl,M.C., Voight,B.F.,
            Vollenweider,P., Waeber,G., Waterworth,D.M., Watkins,H.,
            Wheeler,E., Widen,E., Wild,S.H., Willems,S.M., Willemsen,G.,
            Wilson,J.F., Witteman,J.C., Wright,A.F., Yaghootkar,H.,
            Zelenika,D., Zemunik,T., Zgaga,L., Wareham,N.J., McCarthy,M.I.,
            Barroso,I., Watanabe,R.M., Florez,J.C., Dupuis,J., Meigs,J.B. and
            Langenberg,C.
  CONSRTM   DIAbetes Genetics Replication And Meta-analysis (DIAGRAM)
            Consortium; Multiple Tissue Human Expression Resource (MUTHER)
            Consortium
  TITLE     A genome-wide approach accounting for body mass index identifies
            genetic variants influencing fasting glycemic traits and insulin
            resistance
  JOURNAL   Nat Genet 44 (6), 659-669 (2012)
   PUBMED   22581228
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 930)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC023080.6.
            
            On Sep 19, 2004 this sequence version replaced XM_171490.4.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000319988.1/ ENSP00000321447.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-930               AC023080.6         150799-151728       c
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p11.2"
     gene            1..930
                     /gene="OR4S1"
                     /gene_synonym="OR11-100"
                     /note="olfactory receptor family 4 subfamily S member 1"
                     /db_xref="GeneID:256148"
                     /db_xref="HGNC:HGNC:14705"
     CDS             1..930
                     /gene="OR4S1"
                     /gene_synonym="OR11-100"
                     /note="olfactory receptor OR11-100"
                     /codon_start=1
                     /product="olfactory receptor 4S1"
                     /protein_id="NP_001004725.1"
                     /db_xref="CCDS:CCDS31488.1"
                     /db_xref="GeneID:256148"
                     /db_xref="HGNC:HGNC:14705"
                     /translation="MGAKNNVTEFVLFGLFESREMQHTCFVVFFLFHVLTVLGNLLVI
                     ITINARKTLKSPMYFFLSQLSFADICYPSTTIPKMIADTFVEHKIISFNGCMTQLFSA
                     HFFGGTEIFLLTAMAYDRYVAICRPLHYTAIMDCRKCGLLAGASWLAGFLHSILQTLL
                     TVQLPFCGPNEIDNFFCDVHPLLKLACADTYMVGLIVVANSGMISLASFFILIISYVI
                     ILLNLRSQSSEDRRKAVSTCGSHVITVLLVLMPPMFMYIRPSTTLAADKLIILFNIVM
                     PPLLNPLIYTLRNNDVKNAMRKLFRVKRSLGEK"
     exon            1..930
                     /gene="OR4S1"
                     /gene_synonym="OR11-100"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgggtgcca agaacaatgt gactgagttt gttttatttg gcctttttga gagcagagag
       61 atgcagcata catgctttgt ggtattcttc ctctttcatg tgctcactgt cctggggaac
      121 cttctggtca tcatcaccat caatgctaga aagaccctga agtctcccat gtatttcttc
      181 ctgagccagt tgtcttttgc tgacatatgt tatccatcca ctaccatacc caagatgatt
      241 gctgacactt ttgtggagca taagatcatc tccttcaatg gctgcatgac ccagctcttt
      301 tctgcccact tctttggtgg cactgagatc ttcctcctta cagccatggc ctatgaccgc
      361 tatgtggcca tctgtaggcc cctgcactac acagccatca tggattgccg gaagtgtggc
      421 ctgctagcgg gggcctcctg gttagctggc ttcctgcatt ccatcctgca gaccctcctc
      481 acggttcagc tgcctttttg tgggcccaat gagatagaca acttcttctg tgatgttcat
      541 cccctgctca agttggcctg tgcagacacc tacatggtag gtctcatcgt ggtggccaac
      601 agcggtatga tttctttagc atcctttttt atccttatca tttcctatgt tatcatctta
      661 ctgaacctaa gaagccagtc atctgaggac cggcgtaagg ctgtctccac atgtggctca
      721 cacgtaatca ctgtcctttt ggttctcatg ccccccatgt tcatgtacat tcgtccctcc
      781 accaccctgg ctgctgacaa acttatcatc ctctttaaca ttgtgatgcc acctttgctg
      841 aaccctttga tctatacact aaggaacaac gatgtgaaaa atgccatgag gaagctgttt
      901 agggtcaaga ggagcttagg ggagaagtga
//
