LOCUS       NM_001405963            2165 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily Q member 3
            (OR4Q3), transcript variant 2, mRNA.
ACCESSION   NM_001405963
VERSION     NM_001405963.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2165)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 2165)
  AUTHORS   Rouquier,S., Blancher,A. and Giorgi,D.
  TITLE     The olfactory receptor gene repertoire in primates and mouse:
            evidence for reduction of the functional fraction in primates
  JOURNAL   Proc Natl Acad Sci U S A 97 (6), 2870-2874 (2000)
   PUBMED   10706615
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL512310.4 and KF455839.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000642117.2/ ENSP00000492928.2
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-101               AL512310.4         53648-53748         c
            102-1716            AL512310.4         48299-49913         c
            1717-2034           KF455839.1         1-318
            2035-2165           AL512310.4         47850-47980         c
FEATURES             Location/Qualifiers
     source          1..2165
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q11.2"
     gene            1..2165
                     /gene="OR4Q3"
                     /gene_synonym="C14orf13; c14_5008; HSA6; OR14-3; OR4Q4"
                     /note="olfactory receptor family 4 subfamily Q member 3"
                     /db_xref="GeneID:441669"
                     /db_xref="HGNC:HGNC:15426"
     exon            1..101
                     /gene="OR4Q3"
                     /gene_synonym="C14orf13; c14_5008; HSA6; OR14-3; OR4Q4"
                     /inference="alignment:Splign:2.1.0"
     CDS             100..1065
                     /gene="OR4Q3"
                     /gene_synonym="C14orf13; c14_5008; HSA6; OR14-3; OR4Q4"
                     /note="isoform 2 is encoded by transcript variant 2;
                     olfactory receptor OR14-3; olfactory receptor 4Q3;
                     olfactory receptor, family 4, subfamily Q, member 4;
                     olfactory receptor 4Q4"
                     /codon_start=1
                     /product="olfactory receptor 4Q3 isoform 2"
                     /protein_id="NP_001392892.1"
                     /db_xref="GeneID:441669"
                     /db_xref="HGNC:HGNC:15426"
                     /translation="MSLDILGLMKKEQDSNVTEFVLLGLSSSWELQLFLFLLFLFFYI
                     AIVLGNLLIVVTVQAHAHLLQSPMYYFLGHLSFIDLCLSCVTVPKMLGDFLQQGKSIS
                     FSGCLAQIYFLHFLGASEMFLLTVMAYDRYVAICNPLRYLTVMNPQLCLWLVLACWCG
                     GFIHSIMQVILVIQLPFCGPNELDNFYCDVPQVIKLACMDTYVVEVLVIANSGLLSLV
                     CFLVLLFSYAIILITLRTHFCQGQNKVFSTCASHLTVVSLIFVPCVFIYLRPFCSFSV
                     DKIFSLFYTVITPMLNPLIYTLRNTDMKTAMKKLRIKPCGIPLPC"
     exon            102..2165
                     /gene="OR4Q3"
                     /gene_synonym="C14orf13; c14_5008; HSA6; OR14-3; OR4Q4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccattttg ctggcctgag gctgaagaga gggttgatag gatgaatggc aggataaaat
       61 cttccttcct tgaaaccaca tagcttctga caagcaaaga tgtcacttga tattcttggc
      121 ttgatgaaaa aagaacaaga ttctaatgtg acagaatttg ttcttctggg cctatcatct
      181 tcttgggagc tgcagctatt tctcttctta ctatttttgt ttttttacat tgctattgtc
      241 ctgggaaacc tcttgatagt ggtaacagtg caagcccatg ctcacctgct ccaatctcct
      301 atgtattatt ttttaggtca tctctctttc attgacctat gcctgagctg tgttactgtg
      361 ccaaagatgt taggggattt cctacagcag ggcaagagca tctctttttc aggatgcctg
      421 gcccagatct acttcctcca ctttctagga gccagtgaga tgtttttgct gacagtcatg
      481 gcctatgaca ggtatgttgc catctgtaac cctttgcgct accttacagt catgaacccc
      541 cagctatgcc tttggttggt tcttgcctgc tggtgtgggg gttttatcca ctctatcatg
      601 caggtcatac tagtcatcca gctgcctttc tgtgggccca atgaactgga caacttctac
      661 tgtgatgtcc cacaagtcat caagctggcc tgcatggaca cctatgtggt agaggtgctg
      721 gtgatagcca acagtggtct gctgtctctt gtctgcttct tggtcttact attctcttat
      781 gctatcatcc tgatcaccct gagaacacac ttctgccagg gccagaacaa ggtcttctct
      841 acctgtgctt ctcacctgac agtggtcagc ctgatcttcg tgccatgcgt attcatctat
      901 ttgaggcctt tctgcagctt ctctgtggat aagatattct ccttgtttta cacagtgatt
      961 acacctatgt tgaaccccct catctacaca ctcagaaata ctgatatgaa gacagctatg
     1021 aagaagctga ggataaaacc atgtggcatt ccattgcctt gttaaggaat gagcagaaga
     1081 ggtgatttga aaaacacact ctttcttgga agactcttaa ctcatcttgt acatgggtaa
     1141 aaaccacttt gatgacgttg gtataaaaga ggagatagca taaagattat aatggatcac
     1201 tcttgattac aatttaaaag cataggtggc actctagaaa gccacctatg ccttttgacc
     1261 ataatcaaga gaactcagga actcagtaga atttactggc cacaaacgat aacaagcatt
     1321 aattgaaaga tcaacttttc tatctttatg tctctaagta ctgttcattt attcaatttt
     1381 ttccactttt taatctattc aaatgaaaga agatatatct ctttttgtgt tcagttcctc
     1441 cagcatttaa tgattcctag tgttaggaag ttccttctga tgtctcatca gatccttttc
     1501 tgaagtagtg tgaatttctt tgttctgtta taacaaagcc tgagaacagt aacaaccacc
     1561 tatgtgtagt atttacctca gaactgtgtt ccacagtgtc ccaagtttta gaaatgtagt
     1621 caggcatcag tctaatgaac atatgctctt aacaaagttt atgcgtgaga gaaaggaagt
     1681 ccaggagtgc aggggtgatg gaagctgtta gtattctgtt gtagaggctt ctcaagaaga
     1741 ggtacctagt ttcacactga gtttttcttt gattggaatt acagtggggg tgaatagata
     1801 agctggctct tcaactgacc ataatgttta agagttttaa cctctaaagg aacagaggaa
     1861 gaaatgaact gtgattgaaa gcactcattt ttgagatgct cacagttatt acctctgagt
     1921 ctcaaacatg ctttgaggaa taaatttact taacttcatt tttgagaatg aactcagagt
     1981 taagtgactt gcccatgacc acttagaaga aatgcaatca atcaagaaag ctctttgtaa
     2041 tcccagcact ttgggaggcc agggcaggca gatcatctga agtcaggagt ttgagaccag
     2101 cttgagcaat atggagaaac cccgtctcta ctaaaaatac aaaattagcc ggacgtggtg
     2161 ttgca
//
