LOCUS       NM_001005501            8681 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily K member 2
            (OR4K2), mRNA.
ACCESSION   NM_001005501
VERSION     NM_001005501.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8681)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8681)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL391156.3.
            
            On Aug 7, 2020 this sequence version replaced NM_001005501.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2148874
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641885.1/ ENSP00000493007.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-993               AL391156.3         55691-56683         c
            994-8681            AL391156.3         47893-55580         c
FEATURES             Location/Qualifiers
     source          1..8681
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q11.2"
     gene            1..8681
                     /gene="OR4K2"
                     /gene_synonym="OR14-15"
                     /note="olfactory receptor family 4 subfamily K member 2"
                     /db_xref="GeneID:390431"
                     /db_xref="HGNC:HGNC:14728"
     exon            1..993
                     /gene="OR4K2"
                     /gene_synonym="OR14-15"
                     /inference="alignment:Splign:2.1.0"
     exon            994..8681
                     /gene="OR4K2"
                     /gene_synonym="OR14-15"
                     /inference="alignment:Splign:2.1.0"
     CDS             1017..1961
                     /gene="OR4K2"
                     /gene_synonym="OR14-15"
                     /note="olfactory receptor OR14-15"
                     /codon_start=1
                     /product="olfactory receptor 4K2"
                     /protein_id="NP_001005501.1"
                     /db_xref="CCDS:CCDS32023.1"
                     /db_xref="GeneID:390431"
                     /db_xref="HGNC:HGNC:14728"
                     /translation="MDVGNKSTMSEFVLLGLSNSWELQMFFFMVFSLLYVATMVGNSL
                     IVITVIVDPHLHSPMYFLLTNLSIIDMSLASFATPKMITDYLTGHKTISFDGCLTQIF
                     FLHLFTGTEIILLMAMSFDRYIAICKPLHYASVISPQVCVALVVASWIMGVMHSMSQV
                     IFALTLPFCGPYEVDSFFCDLPVVFQLACVDTYVLGLFMISTSGIIALSCFIVLFNSY
                     VIVLVTVKHHSSRGSSKALSTCTAHFIVVFLFFGPCIFIYMWPLSSFLTDKILSVFYT
                     IFTPTLNPIIYTLRNQEVKIAMRKLKNRFLNFNKAMPS"
ORIGIN      
        1 gtccctacaa catccatttt atccacagct gatacacaac taatgattca actaggtcat
       61 ttatttatat tttaaattgc cttcgatgct ctgtcagaag cctacttaac actgaataat
      121 ctaaagccct ggttcttcta tagatctgat aagtaaaagt gttttacaaa tgagttctac
      181 tgaaatattt taaatgtttg cccttcccac tcccatttcc taatccctat tccatgaagc
      241 ttaggtcaat acaacagttt acatatgtta acatttacag aagaagaatt caaacagagg
      301 tgaaatgaaa gagactgatc tttgagcact ttcccatgaa aatgttgtta tatatccttt
      361 gtgatataaa attttaaatc atagaattat aaatatttat aaggaacaca gtcatatttt
      421 aattaaaaag aaaggaccaa aagaagttaa atgcctttcc tttgtctgta tgactgtatt
      481 gtaataaatt agtctctctg gatgaatatc agcaaaacta actttctatg tatttctttt
      541 gagtttcaaa caggaaactt tatctgggaa tactttaaca gttcatctct ggaaatttac
      601 aagagctcta caactgtcca tcgaaacttc actataatgt gcttaagagc ccttatatgt
      661 gatataattt ttatatgttt tcatcagtaa ggatatcttt atggacaaat tccaaatgac
      721 taaacatgta tgtgtatgtg tgtttcacac attgtcagca taaagtaagt tcttactgtt
      781 atcgttagac ttacacagat gaatagatgg acaaataggt aggtatgtct gttcagaatg
      841 atattatctt ggttggattg ccattagtat cagaaaagaa agtgttcttt tcaataccta
      901 tgatttaagg aacattttgc tataagctct aatatttcat aatttccatt caaaacaata
      961 taccaaatga gaaggatgga aagaatagtc aaggcttctg cctatgaatc aagacaatgg
     1021 atgtgggcaa taagtctacc atgtctgaat ttgttttgct ggggctctct aattcctggg
     1081 aactacagat gtttttcttt atggtgtttt cattgcttta tgtggcaaca atggtgggta
     1141 acagcctcat agtcatcaca gttatagtgg accctcacct acactctcct atgtatttcc
     1201 tgcttaccaa tctttcaatc attgatatgt ctcttgcttc tttcgccacc ccaaagatga
     1261 ttacagatta cctaacaggt cacaaaacca tctcttttga tggctgcctt acccagatat
     1321 tctttctcca ccttttcact ggaactgaga tcatcttact catggccatg tcctttgata
     1381 ggtatattgc aatatgcaag cccctgcact atgcttctgt cattagtccc caggtgtgtg
     1441 ttgctctcgt ggtggcttcc tggattatgg gagttatgca ttcaatgagt caggtcatat
     1501 ttgccctcac gttaccattc tgtggtccct atgaggtaga cagctttttc tgtgaccttc
     1561 ctgtggtgtt ccagttggct tgtgtggata cttatgttct gggcctcttt atgatctcaa
     1621 caagtggcat aattgcgttg tcctgtttta ttgttttatt taattcatat gttattgtcc
     1681 tggttactgt gaagcatcat tcttccagag gatcatctaa ggccctttct acttgtacag
     1741 ctcatttcat tgttgtcttc ttgttctttg ggccatgcat cttcatctac atgtggccac
     1801 taagcagctt tctcacagac aagattctgt ctgtgtttta taccatcttt actcccactc
     1861 tgaacccaat aatctatact ttgaggaatc aagaagtaaa gatagccatg aggaaactga
     1921 aaaataggtt tctaaatttt aataaggcaa tgccttcata gtttttgtga cacagaacat
     1981 tagacacaat gctgtgttag gcttttcttt ctagagggtt cttaccaaat tgtaattgcc
     2041 aagaatttgt gagggctcaa gttcagtgca ttttgaaact attctcatga atgtgaatgt
     2101 gttcaaaata catttgaaat ttcagaaaag caagttaaaa gaaataaaga ctataaaaat
     2161 gtcaggagtg acagttccag ttaggacatt caatatcaat aatcaattta ttggaaaaga
     2221 ggaccaagga atgaggagaa gaaatataga ttaaagcaga actaggagat aatgacaatt
     2281 acccacagtg agcaactgag tcacttagtg agatgctcct aaagtatgac aagctagcaa
     2341 gattcctata atccttagga actccatact gctgtaggat cttagcctct gacagagaag
     2401 caatgatttt ccacatacgt tcccaagcca ctcctactta acatttaaac caatttgtga
     2461 tctcttctat taaagaaaac tctagatata ttttatttcg aatgttaatg acgtccataa
     2521 aattgccgta agtgtagcaa tctttaccaa ccacttttag ttcatcatca aagcaataca
     2581 gtcatgatat ttctttctga taatgcggaa tgagtaggga ggctggagaa ttctgcaaat
     2641 cagaaaatat gaaatgagtt gcagatcagt acactttgtt ttgtgcagac acgatggttg
     2701 cttagttcct aagaagttaa aactagaatt gagagacaca gtttataaca gttgaattta
     2761 tggggagtcc atgctttcat tttaaagtgt tatattgctt tccattttgg ttattttttt
     2821 cttgaaatat ttggatgtaa aaataatgaa tctgcattta gtaatacatt gtcaatgtaa
     2881 taagtatgtt tttgtacaca aataggtttt attactgtta taaataaatc tggtaggttc
     2941 aatattagct ttaatgtata caaagtatta ctaccacctg ctggtactaa ctggaattgc
     3001 aagtattgaa agaggaaaaa taattgtgta taccctactt tgcaaatcat ctttaaatga
     3061 tggcaaacat tcatgagtta actcttattt agaattttct aaatgatatt gataaaatat
     3121 agtgtcttat atatgatcca acatgtatcc acaaagggaa agatatgttg caaccacagt
     3181 atttgataat atcaagttgt tattttctgg tatgattgag taaatggaga aaacaaatga
     3241 aatgcattaa ttatcattta tgaaagataa ttaaaacaga aaatccttag atgttcatat
     3301 taaaccaagt tataaaagga atttattttt tcttcatcag tttgtgtttt atttcttcat
     3361 taatgtacta agcaaataag gaaaaaactt acagcttgaa agtctgtgat actgtgttta
     3421 aagcctgagc agttttgaaa ttattagata ataacgtcta cagtattaac ataaaataaa
     3481 acatgcttct gtaagcacaa gattagcata attctatttt aaatagggat acaaataggc
     3541 caatttaggt tttgagtgtg aactttctct tggttgcagt tatatgtaca aatatgttca
     3601 tattcaagga cttcgtttat gtagaatgtt ttagctggtg cttaaaaatg ctagaaataa
     3661 ttcttttact tgacatattt ctttgtccag ggaatatttt caaaactgtg ctgctttttg
     3721 caatataaaa ctgtggaatc ttttggaaga gacgctattg attttctgtg cttttgtgga
     3781 gaattctaaa actcaagaac atttgccaaa ataccctcaa aggtgtagct gatcagcaga
     3841 caactctata aggcaagtca ataatgagat taagtagttg gattgatagt aaaattctgt
     3901 ggctgataat aaaaaggatt acagaaagcc tttggagggc ttacatatat aaatggaact
     3961 atcacatttc tcggtggctt agtgtgagga gtcaatattc atggtacctc tgcatgttat
     4021 ataaacactt aaaaatctta gttaggactt taggactcat ggtggttggt tttatcgata
     4081 tatctcttag acaagatgct gacactcttt caccaaggat aactgcagtg acatggccat
     4141 ggactcgtta agcaatagta aggatggtgc cagctgccac cagagtttcc agagacagag
     4201 ataatgttct gcagagaata caagataagc aggcaagtat aattttaagt gatctgcact
     4261 atctgcaata acacaactga gggagttctg gagcatttat aagaagagtg tgttgacaag
     4321 caacttcatc ttcctctacg tgtttaggaa gctgtgaagc ttgacaacaa ttgaatgcag
     4381 atggaaaaac tgttaaaaat caggtataga taaaaacaga taaagtgtaa attttaatat
     4441 gtgaaggaac tggatatatg taatagcaat aaaaactaca aattatgttt gtttctaaaa
     4501 atgcttaaga aaacttttag aatactatat ggtataatga tggtggattt accataaagc
     4561 ttgtaaagct taggttttat aactcctcct ttgcatggat ttcctcgaag gccctagaat
     4621 ggaaactaac aaccttttat tagttatttc gatttttttt tcctgaaaca ggtgtcctca
     4681 aactgtataa gctttaagcc tagcttgtcc aacccatgac ctgcaggttg catgcggctc
     4741 aggagatggc tttaaattca gcccaacaca aattcataag ctttcttgaa acattataag
     4801 attttcttgt gatttttttg taaagctcat cagctatctt tagtatcagt gtattttatg
     4861 tgtggcccaa cacaattctt cttccaatgt ggcccagaga agccaaaact ttggacaccc
     4921 ctgcattaaa aggctctgca gaatctgaag tctaatgtgt agttttaaaa gtcttagact
     4981 ctggtatctt tttttttttt aaacagtgtt taatactact tctactacta gtggtgtaaa
     5041 cttaagctaa gtacttaata cctcttagcc tcagtttcta catatgttaa aggagataat
     5101 agtggtctct acaccacaga gttatttgag gcataaaaga agcaaataat atgaagcata
     5161 tggttgtcaa taaatgttag tcattgtatc attctgggtg ataacctctg gatatctttg
     5221 tttatgggac ttgatagtct cttgagctaa cacttgactt gtttaattta aaaggtaaat
     5281 tttcatttat atgttttaaa tattcatgtc tgtatatgtg tgtcagtatt aatttgaaaa
     5341 attaaaagta acttccacta gaaaattaca ctggttctta cattaattaa agcttctgga
     5401 aacttgtttt tctgtctgtt cacaactgtc attaatcaag agaagtatca agttgttgct
     5461 taatcattat gctattgctt ctttacaatg aataaatatt aaattggttt attgatttta
     5521 ggatgaattc acattacaat tgttgtcaga ataagaatga tgtttgactc atattattaa
     5581 ggtgaagaga taggcagatg gatagattag tagatagatg aagttttgta ttatatgagc
     5641 tgtcttatgt gaagtatttt tctgcattga taagggttta ggataatgtg atcactggat
     5701 tatgctgcta tatagaagtt cttggtaaaa tgctgttatt tgtgcatatc cagactcctt
     5761 atgaaagtat tttcaaattt aaaaaactac cagtgaatct attctctaca tgtgagtttt
     5821 taaacaactc agttatagca aaatttgttg agagagttgg agtaatcctc ctatttccct
     5881 attctttccc tgatattatt ttgcatgatt tttggatgta tatgtcaatt gaaaaacggg
     5941 gagaagaaaa cagccaggga aatctaattc atgtgaactt cttgcatgta ctctcagatg
     6001 ccaatgaaat ccgctaagca acttgatagt tttttggttt ataagtttct gttgtgcttt
     6061 gttgtttgga attattttta atgctcttgg ttacaccatg aggtaaatat gcacaaatta
     6121 ttctggagcg tgtaggacca acactcaaat gagactggaa atgtgactgg gatcattgat
     6181 tcatgtattc tgtctctatt gttgctaata taactcaatt gacatgttat tttttctctt
     6241 tgatttttgt aaaacaaaca aataaattcc aatatctagt atgcactaaa atactatagt
     6301 ttcattttta ttttttactc tgataattta cactgccaat ataaggagat gaatacctat
     6361 tttttaaatt aaaaaatgtt ctcgggctgg aggctccagg tttttttccc ccattagcct
     6421 ttttatgact actaaatgca agaccactgt taattcgcct tttttctttg tgttttaact
     6481 gtactaggaa tctgaagcca tcaacaaaag ccagattttt ctccctttgc tcacttgcca
     6541 cctgttaaag aaaatttaaa ggagagattt ttttttttag tttgagacta gaaatagcaa
     6601 tttaattagt aatttgtttt tatataataa tatatttata tcaatttttt cttcttgttt
     6661 gagtgtactt atattggttg tcctacagtt aagaaaacgg aaaccattgg gtaaattaag
     6721 cagatttaat acaatgtatt aaatgcttgt gaataattca aagacttaca ggaacatgca
     6781 ttggaggctg caactggagc tattgtgttc cagagcacat taccccagta atgtgatgta
     6841 agggcaaaag gcaaaaagcc ttggtgtcat tgccactcct tcatcaccct cagcactctt
     6901 gaaggtggtg aatagtcact ggacacaggt atggctgcca cagttgcttt ccctcacatc
     6961 tcatcatcat cttgctcacc agcggcaatt atatcagtag atccctctgc ctcacttgtg
     7021 ctttctaaag ctcatttggt gcatctaatt ggtggaatct attttgcaca gagaaacttg
     7081 gcttcaaaaa tcaatttgta gatttcaaga ttcttatgca acagaaaaca tgctaataga
     7141 gggtggattg gagggagact ccgtcaatca atcaatatcc attactttaa tttttttatt
     7201 ataacctttt tattgcagtg taaaagcaag gtaaagaaaa atacacaaac atgtttagct
     7261 taatgaaata ttacaaggca aacaccatta taatcacatt tcaagtcaca aaatagaact
     7321 tcgccagcca cccctgaagt cctcaagttt gttcatctcg atgacaactc tctcctccaa
     7381 aattaaccat taccctgact taataaatta tttgcatttc ttttcagttt catgaataca
     7441 tatatactca aatatacatc catacacact caaacttggc ctcaccaact ttgtttcctt
     7501 ttcttgtagc ctacaagtct cactatcact atctcttcaa tttctgtata atttatcttt
     7561 ctttttcttt tttttttctt tttttttttt ttttgagacg gagtcttgct ctgtcgccca
     7621 ggctggagtg cagtagcgtg atctccgctc attgcaaact ctgccttccg gattcacgcc
     7681 attctcctgc ctcagcctcc tgagtagctg ggactacagg cgcccgccac cacgcccagc
     7741 taattttttg tatttttagt agagaagggg ttataattta tcttttgaaa aacctgagtt
     7801 atttaccatc tagggtctcc cagagtctga aatatgctga ttgcatgctc atggtacagt
     7861 tcaacatgga cttctgtcac tgcattttct gcaaattgcc tatccagcag cttaatcata
     7921 tttagtttga tactttttgc aagacaaatg acagatgatg ttatattttt tcatccaaaa
     7981 gatcttgatg tcttgcttta tctctttggg aatgatagtg ctgttgttgc tgtagtagtt
     8041 gatatctcta accatttttg ttggctgaag cttattctct actatattcc tcaggaagtc
     8101 ttcttgaaga ccctattctc tgaattctgg cgtgttggca agtttctttg aaacatttat
     8161 gtactgtaat ttcattggct attcctttat tttcttgatt atcttaaatt gaaataatga
     8221 ctctctttgt aagcactttg tctggagtct gcaaagcctg tatttttctt cactcaccct
     8281 agcataccat ataattagaa gtttggaact gatcttttaa tttttggagg gaggtattaa
     8341 taatccttct gatatttata ttagtagtta aataattaaa tagtagttaa agtaattaaa
     8401 taggactcta ttgcactcaa gagattttaa aacgtttaaa tttctaaatt tcctttaagt
     8461 atattaaaat gtacctaaat aaaattgttc ttcaagagta acatgtaatt gaatcatcaa
     8521 catctttata taacttttcc aattttttaa agaaagatac ctctcttgca gctcaattgc
     8581 tttttaaata aaataaattt gaatccctgt ttgtacctgg agaccgtttt gatctgccct
     8641 cctcacctca catttcacac atggagaaaa aaagtctgca c
//
