LOCUS       NM_001004063            1339 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily K member 1
            (OR4K1), mRNA.
ACCESSION   NM_001004063
VERSION     NM_001004063.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1339)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 1339)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL391156.3 and AL359218.4.
            
            On Aug 3, 2020 this sequence version replaced NM_001004063.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641172.1/ ENSP00000493193.1
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-229               AL391156.3         680-908             c
            230-1339            AL359218.4         151272-152381       c
FEATURES             Location/Qualifiers
     source          1..1339
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q11.2"
     gene            1..1339
                     /gene="OR4K1"
                     /gene_synonym="OR14-19"
                     /note="olfactory receptor family 4 subfamily K member 1"
                     /db_xref="GeneID:79544"
                     /db_xref="HGNC:HGNC:14726"
     exon            1..229
                     /gene="OR4K1"
                     /gene_synonym="OR14-19"
                     /inference="alignment:Splign:2.1.0"
     exon            230..1339
                     /gene="OR4K1"
                     /gene_synonym="OR14-19"
                     /inference="alignment:Splign:2.1.0"
     CDS             249..1184
                     /gene="OR4K1"
                     /gene_synonym="OR14-19"
                     /note="olfactory receptor OR14-19"
                     /codon_start=1
                     /product="olfactory receptor 4K1"
                     /protein_id="NP_001004063.2"
                     /db_xref="CCDS:CCDS32025.1"
                     /db_xref="GeneID:79544"
                     /db_xref="HGNC:HGNC:14726"
                     /translation="MAHTNESMVSEFVLLGLSNSWGLQLFFFAIFSIVYVTSVLGNVL
                     IIVIISFDSHLNSPMYFLLSNLSFIDICQSNFATPKMLVDFFIERKTISFEGCMAQIF
                     VLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMNRRLCVIFVSISWAVGVLHSVSHL
                     AFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYEMEIMTLTNSGLISLSCFLALIISY
                     TIILIGVRCRSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLPVDKFLSVFYT
                     VCTPLLNPIIYSLRNEDVKAAMWKLRNRHVNSWKN"
ORIGIN      
        1 aggtgatcag agccctcact acatcaggac aggacctgag gacctgagag gcttccttcc
       61 atacggcata gtgtagggaa ccaagttaaa atgcatcaag ttaagattat attacaaata
      121 ttttcagtat gaagactcat agcagaaagt gggaaatgga aacaaaccag aggacaccaa
      181 actgggaaaa taaggaagaa gtgaaagact tggacaactt tttcaaagtg taactgaata
      241 ttggatacat ggctcacaca aatgaatcga tggtgtctga gtttgtactt ttgggactct
      301 ctaattcctg gggacttcaa cttttctttt ttgccatctt ctctatagtc tatgtgacat
      361 cagtgctagg caatgtctta attattgtca ttatttcttt tgactcccat ttgaactctc
      421 ctatgtactt cttgctcagt aatctttctt tcattgatat ctgtcagtct aactttgcca
      481 cccccaagat gcttgtagac ttttttattg agcgcaagac tatctccttt gagggttgca
      541 tggcccagat attcgttctt cacagttttg ttgggagtga gatgatgttg cttgtagcta
      601 tggcatatga cagatttata gccatatgta agcctctgca ctacagtaca attatgaacc
      661 ggaggctctg tgtaattttt gtgtctattt cctgggcggt gggcgttctt cattctgtga
      721 gccacttggc ttttacagtg gacctgccat tctgtggtcc caatgaggtg gatagcttct
      781 tttgtgacct tcccttggtg atagagctgg cttgcatgga tacatatgaa atggaaatta
      841 tgaccctaac gaacagtggc ctgatatcat tgagctgttt cctggcttta attatttcct
      901 acaccatcat tttgatcggt gtccgatgca ggtcctccag tgggtcatct aaggctcttt
      961 ctacattaac tgcccacatc acagtggtca ttcttttctt cgggccttgc atttatttct
     1021 atatatggcc ttttagcaga cttcctgtgg acaaatttct ttctgtgttc tacactgttt
     1081 gtactccctt gttgaacccc atcatctact ctctgaggaa tgaagatgtt aaagcagcca
     1141 tgtggaagct gagaaaccgt catgtgaact cctggaaaaa ctagggatca ttacgaagga
     1201 gcataatcct gaattagaat gaagaccctc cagtgtatca tagtgtcatg ccaaccatct
     1261 ttgccagaca tatgggttat tgagttacag aattggcttt ttgttttaag tgcaagggaa
     1321 ttgcatcaag tcagtctct
//
