LOCUS       NM_001005240            2669 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily F member 17
            (OR4F17), transcript variant 1, mRNA.
ACCESSION   NM_001005240 XM_005259648
VERSION     NM_001005240.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2669)
  AUTHORS   Linardopoulou,E., Mefford,H.C., Nguyen,O., Friedman,C., van den
            Engh,G., Farwell,D.G., Coltrera,M. and Trask,B.J.
  TITLE     Transcriptional activity of multiple copies of a subtelomerically
            located olfactory receptor gene that is polymorphic in number and
            location
  JOURNAL   Hum Mol Genet 10 (21), 2373-2383 (2001)
   PUBMED   11689484
REFERENCE   2  (bases 1 to 2669)
  AUTHORS   Mefford,H.C., Linardopoulou,E., Coil,D., van den Engh,G. and
            Trask,B.J.
  TITLE     Comparative sequencing of a multicopy subtelomeric region
            containing olfactory receptor genes reveals multiple interactions
            between non-homologous chromosomes
  JOURNAL   Hum Mol Genet 10 (21), 2363-2372 (2001)
   PUBMED   11689483
REFERENCE   3  (bases 1 to 2669)
  AUTHORS   Trask,B.J., Friedman,C., Martin-Gallardo,A., Rowen,L., Akinbami,C.,
            Blankenship,J., Collins,C., Giorgi,D., Iadonato,S., Johnson,F.,
            Kuo,W.L., Massa,H., Morrish,T., Naylor,S., Nguyen,O.T.,
            Rouquier,S., Smith,T., Wong,D.J., Youngblom,J. and van den Engh,G.
  TITLE     Members of the olfactory receptor gene family are contained in
            large blocks of DNA duplicated polymorphically near the ends of
            human chromosomes
  JOURNAL   Hum Mol Genet 7 (1), 13-26 (1998)
   PUBMED   9384599
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008977.9.
            
            On Nov 17, 2020 this sequence version replaced NM_001005240.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY972817.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000585993.3/
                                                ENSP00000467301.1
            RefSeq Select criteria           :: based on manual assertion,
                                                conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                AC008977.9         13856-13909
            55-137              AC008977.9         14225-14307
            138-2669            AC008977.9         17377-19908
FEATURES             Location/Qualifiers
     source          1..2669
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.3"
     gene            1..2669
                     /gene="OR4F17"
                     /gene_synonym="OR4F11P; OR4F18; OR4F19; OR4F5"
                     /note="olfactory receptor family 4 subfamily F member 17"
                     /db_xref="GeneID:81099"
                     /db_xref="HGNC:HGNC:15381"
     exon            1..54
                     /gene="OR4F17"
                     /gene_synonym="OR4F11P; OR4F18; OR4F19; OR4F5"
                     /inference="alignment:Splign:2.1.0"
     exon            55..137
                     /gene="OR4F17"
                     /gene_synonym="OR4F11P; OR4F18; OR4F19; OR4F5"
                     /inference="alignment:Splign:2.1.0"
     exon            138..2669
                     /gene="OR4F17"
                     /gene_synonym="OR4F11P; OR4F18; OR4F19; OR4F5"
                     /inference="alignment:Splign:2.1.0"
     CDS             192..1109
                     /gene="OR4F17"
                     /gene_synonym="OR4F11P; OR4F18; OR4F19; OR4F5"
                     /note="isoform 1 is encoded by transcript variant 1;
                     olfactory receptor, family 4, subfamily F, member 11
                     pseudogene; olfactory receptor, family 4, subfamily F,
                     member 19; olfactory receptor 4F17; olfactory receptor
                     4F11; olfactory receptor 4F18; olfactory receptor 4F19"
                     /codon_start=1
                     /product="olfactory receptor 4F17 isoform 1"
                     /protein_id="NP_001005240.1"
                     /db_xref="CCDS:CCDS32854.1"
                     /db_xref="GeneID:81099"
                     /db_xref="HGNC:HGNC:15381"
                     /translation="MVTEFIFLGLSDSQGLQTFLFMLFFVFYGGIVFGNLLIVITVVS
                     DSHLHSPMYFLLANLSLIDLSLSSVTAPKMITDFFSQRKVISFKGCLVQIFLLHFFGG
                     SEMVILIAMGFDRYIAICKPLHYTTIMCGNACVGIMAVAWGIGFLHSVSQLAFAVHLP
                     FCGPNEVDSFYCDLPRVIKLACTDTYRLDIMVIANSGVLTVCSFVLLIISYTIILMTI
                     QHRPLDKSSKALSTLTAHITVVLLFFGPCVFIYAWPFPIKSLDKFLAVFYSVITPLLN
                     PIIYTLRNKDMKTAIRQLRKWDAHSSVKF"
ORIGIN      
        1 tttttatgcc tcattctgtg aaaattgctg tagtctcttc cagttatgaa gaaggtccgg
       61 tgttttctta cccacctcct tccctccttt ttataatacc agtgaaactt ggtttggagc
      121 atttctttca cataaaggta actgcagagg ctatttcctg gaatgaatca acgagtgaaa
      181 cgaataactc tatggtgact gaattcattt ttctgggtct ctctgattct cagggactcc
      241 agaccttcct atttatgttg ttttttgtat tctatggagg aatcgtgttt ggaaaccttc
      301 ttattgtcat aacagtggta tctgactccc accttcactc tcccatgtac ttcctgctag
      361 ccaacctctc actcattgat ctgtctctgt cttcagtcac agcccccaag atgattactg
      421 actttttcag ccagcgcaaa gtcatctctt tcaagggctg ccttgttcag atatttctcc
      481 ttcacttctt tggtgggagt gagatggtga tcctcatagc catgggcttt gacagatata
      541 tagcaatatg caaaccccta cactacacta caattatgtg tggcaacgca tgtgtcggca
      601 ttatggctgt cgcatgggga attggctttc tccattcggt gagccagttg gcctttgccg
      661 tgcacttacc cttctgtggt cccaatgagg tcgatagttt ttattgtgac cttcctaggg
      721 taatcaaact tgcctgtaca gatacctaca ggctagatat tatggtcatt gctaacagtg
      781 gtgtgctcac tgtgtgttct tttgttcttc taatcatctc atacactatc atcctaatga
      841 ccatccagca tcgcccttta gataagtcgt ccaaagctct gtccactttg actgctcaca
      901 ttacagtagt tcttttgttc tttggaccat gtgtctttat ttatgcctgg ccattcccca
      961 tcaagtcatt agataaattc cttgctgtat tttattctgt gatcacccct ctcttgaacc
     1021 caattatata cacactgagg aacaaagaca tgaagacggc aataagacag ctgagaaaat
     1081 gggatgcaca ttctagtgta aagttttaga tcttatataa ctgtgagatt aatctcagat
     1141 aatgacacaa aatatagtga agttggtaag ttatttagta aagctcatga aaattgtgcc
     1201 ctccattccc atataattta ttaattgtct aggaacttcc acatacattg cctcaattta
     1261 tctttcaaca acttgtgtgt tatattttgg aatacagata caaagttatt atgctttcaa
     1321 aatattcttt tgctaattct tagaacaaag aaaggcataa atatattagt atttgtgtac
     1381 atctgttcct tcctgtgtga ccctaagttt agtagaagaa aggagagaaa atatagccta
     1441 gcttataaat ttaaaaaaaa atttatttgg tccattttgt gaaaaacata aaaaaagaac
     1501 tgtcacatct taatttaaaa aatatatgct tagtggtaag gagatatatg tcaactttta
     1561 agaggttgaa aaacaaacgc ctcccattat aagtttatac ttcacctccc accactataa
     1621 caacccagaa tccatgaggg cattatcagg agtgagtgga agagtaagtt tgccaatgtg
     1681 aaatgtgcct tctaggtcct agacatctgt ggtataactg ctcataagca gtagaaagaa
     1741 tttagaggga tccaggctct catcacgttg gcacaaagta tattacttgg atccatctat
     1801 gtcattttcc atggttaatg tttaaaacca caggctttaa agtaaaaaac aaagagctgg
     1861 attcaactct actgactctt attaatcatg attttgggca cattacgtag ctttcatgag
     1921 ctttagtttc tacatttata aacaggagat tatacctatt atgcacggtt attatgaagg
     1981 aaaatgacaa aatagatata aatcaaatag cccacttcga gacatattaa gcatgaataa
     2041 acattagata ctattaaaat cctatatatt aacaaagcca aaagtttcaa actttacttt
     2101 ttcccaacat tcttgtgaaa tatgacacat cccaatctta acagatgctc atttgggata
     2161 ctgtacttgt gagtggaagt gtgtatattt gtgtgcaagt gtgtactcat atacttccac
     2221 cttaccaccc tagaaaggca tgatgaaaat ttaagataga aggaaaatat aaattgaaaa
     2281 aaaaaaacct taacaaatga ttctgacaaa tatcttctct ttccagggag aatcactgag
     2341 ccagaataaa attgaacact aaatattcta agaaaaaagg aatctagttt gtcaaaatgt
     2401 gacttgaatt aatagataag gagagtcaga tgataagagg gtcaaaatta tgtttatctt
     2461 aggaaaagta gaatagaaaa tttataagca gattaaaaac acataataaa agtagtaaat
     2521 aataatgaca gtatctcaaa tcagtgcagg ggggaaaggc ctactaatgt gatggtggga
     2581 taattggata gcaatatggg aaaagatata tttaatttat ttgctacacc aaatgccagg
     2641 acaatctcta agtgaattca agacataac
//
