LOCUS       NM_001001912            2855 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily E member 2
            (OR4E2), mRNA.
ACCESSION   NM_001001912
VERSION     NM_001001912.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2855)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (bases 1 to 2855)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
REFERENCE   3  (bases 1 to 2855)
  AUTHORS   Boysen,C., Simon,M.I. and Hood,L.
  TITLE     Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with
            bacterial artificial chromosome clones
  JOURNAL   Genome Res 7 (4), 330-338 (1997)
   PUBMED   9110172
REFERENCE   4  (bases 1 to 2855)
  AUTHORS   Koop,B.F., Rowen,L., Wang,K., Kuo,C.L., Seto,D., Lenstra,J.A.,
            Howard,S., Shan,W., Deshpande,P. and Hood,L.
  TITLE     The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region:
            organization, sequence, and evolution of 97.6 kb of DNA
  JOURNAL   Genomics 19 (3), 478-493 (1994)
   PUBMED   8188290
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC243972.3.
            
            On Aug 4, 2020 this sequence version replaced NM_001001912.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641524.1/ ENSP00000493386.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               AC243972.3         113838-113942       c
            106-193             AC243972.3         111188-111275       c
            194-287             AC243972.3         107031-107124       c
            288-2855            AC243972.3         100135-102702       c
FEATURES             Location/Qualifiers
     source          1..2855
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q11.2"
     gene            1..2855
                     /gene="OR4E2"
                     /gene_synonym="OR14-42"
                     /note="olfactory receptor family 4 subfamily E member 2"
                     /db_xref="GeneID:26686"
                     /db_xref="HGNC:HGNC:8297"
     exon            1..105
                     /gene="OR4E2"
                     /gene_synonym="OR14-42"
                     /inference="alignment:Splign:2.1.0"
     exon            106..193
                     /gene="OR4E2"
                     /gene_synonym="OR14-42"
                     /inference="alignment:Splign:2.1.0"
     exon            194..287
                     /gene="OR4E2"
                     /gene_synonym="OR14-42"
                     /inference="alignment:Splign:2.1.0"
     exon            288..2855
                     /gene="OR4E2"
                     /gene_synonym="OR14-42"
                     /inference="alignment:Splign:2.1.0"
     CDS             296..1237
                     /gene="OR4E2"
                     /gene_synonym="OR14-42"
                     /note="olfactory receptor OR14-42"
                     /codon_start=1
                     /product="olfactory receptor 4E2"
                     /protein_id="NP_001001912.2"
                     /db_xref="CCDS:CCDS41916.1"
                     /db_xref="GeneID:26686"
                     /db_xref="HGNC:HGNC:8297"
                     /translation="MDSLNQTRVTEFVFLGLTDNRVLEMLFFMAFSAIYMLTLSGNIL
                     IIIATVFTPSLHTPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCITQLF
                     FLHLFACAEIFLLIIMAYDRYVAICTPLHYPNVMNMRVCIQLVFALWLGGTVHSLGQT
                     FLTIRLPYCGPNIIDSYFCDVPLVIKLACTDTYLTGILIVTNSGTISLSCFLAVVTSY
                     MVILVSLRKHSAEGRRKALSTCSAHFMVVALFFGPCIFIYTRPDTSFSIDKVVSVFYT
                     VVTPLLNPFIYTLRNEEVKSAMKQLRQRQVFFTKSYT"
ORIGIN      
        1 aatttaccct gtgcagaatt ttgagtttca tgattttata tcctaggctt ctataatagg
       61 gtatcagagg cgaatggaat cattagagga gatacagagt agatgaaaca attatgagaa
      121 aagtgaatga aataacatta tagtaacttt ataacaatta gctaaagcat ccctgcacaa
      181 ctggagaaaa ctgatggcat ctcgctgtgc tgcctaggca gaccttgaac ttctggactt
      241 aagcgataga tcctccacct cagcctcttg agtatttggg actacagctc attgaatgga
      301 cagtctaaac caaacaagag tgactgaatt tgtcttcttg ggactcactg ataaccgggt
      361 gctggaaatg ctgtttttca tggcattctc agccatttat atgctaacgc tttcggggaa
      421 cattctcatc atcattgcca cagtctttac tccaagtctc cataccccca tgtatttctt
      481 cctgagcaat ctgtccttta ttgacatctg ccactcatct gtcactgtgc ctaagatgtt
      541 ggagggtttg cttttagaaa gaaagaccat ttcctttgac aactgcatca cacagctctt
      601 cttcctacat ctctttgcct gtgccgagat ctttctgctg atcattatgg cgtatgatcg
      661 ttacgtggct atctgcactc cactccacta ccccaatgtg atgaacatga gagtctgtat
      721 acagcttgtc tttgctctct ggttgggggg tactgttcac tcactagggc agaccttctt
      781 gactattcgt ctaccttact gtggccccaa cattattgac agctacttct gtgatgtgcc
      841 tcttgttatc aagctggcct gcacagatac atacctcaca ggaatactga ttgtgaccaa
      901 tagtggaacc atctccctct cctgtttctt ggccgtggtc acctcctata tggtcatcct
      961 ggtttctctt cgaaaacact cagctgaagg gcgccggaaa gccctgtcta cctgctcggc
     1021 ccacttcatg gtggttgccc tcttctttgg gccatgtatc ttcatctata ctcggccaga
     1081 caccagcttc tccattgaca aggtggtgtc tgtcttctac acagtggtca cccctttgct
     1141 gaatcccttc atttacacct tgaggaatga ggaggtaaaa agtgccatga agcagctcag
     1201 gcagagacaa gtttttttca cgaaatcata tacataatgg gcactgggat tgcagacata
     1261 attgcagcca catccttaat gaaagagcaa aagtaaagag tcaaaatcaa cttatataac
     1321 ttggtaaatt aggtaaaatg gcatagagca ggtcagattt ctgctcatta aagataagaa
     1381 cttattctgt tcattaaaga taagaactta ttaactatta tttaaataaa gcaaaagatc
     1441 atagtggaag ttataaggaa aaataacgtg ggaaagttta aagacagctt ttgatttcat
     1501 cagtaaaaga atacaatttg gggaactcag ttcagtctca gtttcaggag caggtagagt
     1561 gagaattgac tctcttgatt tatactgttc tgtgggctat tgcctctggg aagctataca
     1621 tcactcctgt gatttataca ttatagtagt ttcaatcttg ttttccaata tattttcaag
     1681 tgtataaata agcctttact tatttatatt gaattaaact tttgttgctt ttgaatgtaa
     1741 ttctctcatg tctagatcta ttttgtactt tttttttgag acaggaattt tttgtactat
     1801 tcctgcaact tcctgtaagt ctgaaattat tgtcaaaata aaaagttaaa acaaaacaaa
     1861 actatacacc cacaagaata gtaaaaatta aaaaggtaga aaataccaag tggttttttt
     1921 tttttttttc ctaattactc tgtcgcccag gctggagtgc agtggcgcca tcttagctca
     1981 ctgcaacttc cacctccagg tttaagtgat tctcctgcct cagcctcctg aatagctggg
     2041 actataggtg catgccatca tgcctggcta atttttatat gtttagtaga gatgaggttt
     2101 taccacgttg gccaggctgg tctcaaaact cctgagttca agccacctgc ccctctcagc
     2161 taatcattaa ctactatcac tcattgggct gaagtatatc agtttattgt ggaatgggca
     2221 agtccatatg aagagggatc catgacaaat ttcttaggta atgatgatga tattctgtga
     2281 ctgaaataag taggattagc tgtaaatgaa gatcctatag atggtcagag agctaccata
     2341 caatatcaac tttaatggag ctgatggaat gaaatgaaat atggttaata ataaaaatat
     2401 taagtataaa tatgtttctt tgcttattct gaaaaaaatt tataattgat tggggtcttt
     2461 gtcactattt tccacatggt ctgtcaactt atagaaataa tacttgagta ttctggagaa
     2521 ctggagagca gacaacatag ccatccacac attacagaca tacacaatac agagtgagtg
     2581 acccactaac tctaactaaa gagtaataca tgattacctt ttagtaatca aaaggacaaa
     2641 gaatcagaag cagtctattc attaaactga gagatgctca tgaaaatatc taaatatcat
     2701 tacttcaagt tgacaaacaa gggtagaaaa tggtcagtcc cctataattc tcatataaaa
     2761 cttgagtcat agtaagagtt ttagatatct atgatgaaat gaagtccaga tatcactact
     2821 atgtacatgt taaaaactta gaaaaatgat ctaat
//
