LOCUS       NM_001004708             945 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily D member 6
            (OR4D6), mRNA.
ACCESSION   NM_001004708 XM_166900
VERSION     NM_001004708.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Li,B., Kamarck,M.L., Peng,Q., Lim,F.L., Keller,A., Smeets,M.A.M.,
            Mainland,J.D. and Wang,S.
  TITLE     From musk to body odor: Decoding olfaction through genetic
            variation
  JOURNAL   PLoS Genet 18 (2), e1009564 (2022)
   PUBMED   35113854
  REMARK    GeneRIF: From musk to body odor: Decoding olfaction through genetic
            variation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  AUTHORS   McRae,J.F., Jaeger,S.R., Bava,C.M., Beresford,M.K., Hunter,D.,
            Jia,Y., Chheang,S.L., Jin,D., Peng,M., Gamble,J.C., Atkinson,K.R.,
            Axten,L.G., Paisley,A.G., Williams,L., Tooman,L., Pineau,B.,
            Rouse,S.A. and Newcomb,R.D.
  TITLE     Identification of regions associated with variation in sensitivity
            to food-related odors in the human genome
  JOURNAL   Curr Biol 23 (16), 1596-1600 (2013)
   PUBMED   23910658
  REMARK    Erratum:[Curr Biol. 2013 Sep 9;23(17):1718]
REFERENCE   3  (bases 1 to 945)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   4  (bases 1 to 945)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB065803.1.
            
            On Sep 19, 2004 this sequence version replaced XM_166900.3.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000300127.3/ ENSP00000300127.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..945
                     /gene="OR4D6"
                     /gene_synonym="OR11-250"
                     /note="olfactory receptor family 4 subfamily D member 6"
                     /db_xref="GeneID:219983"
                     /db_xref="HGNC:HGNC:15175"
     CDS             1..945
                     /gene="OR4D6"
                     /gene_synonym="OR11-250"
                     /note="olfactory receptor OR11-250"
                     /codon_start=1
                     /product="olfactory receptor 4D6"
                     /protein_id="NP_001004708.1"
                     /db_xref="CCDS:CCDS31562.1"
                     /db_xref="GeneID:219983"
                     /db_xref="HGNC:HGNC:15175"
                     /translation="MDQINHTNVKEFFFLELTRSRELEFFLFVVFFAVYVATVLGNAL
                     IVVTITCESRLHTPMYFLLRNKSVLDIVFSSITVPKFLVDLLSDRKTISYNDCMAQIF
                     FFHFAGGADIFFLSVMAYDRYLAIAKPLHYVTMMRKEVWVALVVASWVSGGLHSIIQV
                     ILMLPFPFCGPNTLDAFYCYVLQVVKLACTDTFALELFMISNNGLVTLLWFLLLLGSY
                     TVILVMLRSHSGEGRNKALSTCTSHMLVVTLHFVPCVYIYCRPFMTLPMDTTISINNT
                     VITPMLNPIIYSLRNQEMKSAMQRLQRRLGPSESRKWG"
     exon            1..945
                     /gene="OR4D6"
                     /gene_synonym="OR11-250"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggaccaga tcaaccacac taatgtgaag gagtttttct tcctggaact tacacgttcc
       61 cgagagctgg agtttttctt gtttgtggtc ttctttgctg tgtatgtagc aacagtcctg
      121 ggaaatgcac tcattgtggt cactattacc tgtgagtccc gcctacacac tcctatgtac
      181 tttctcctgc ggaacaaatc agtcctggac atcgtttttt catctatcac cgtccccaag
      241 ttcctggtgg atcttttatc agacaggaaa accatctcct acaatgactg catggcacag
      301 atctttttct tccactttgc tggtggggca gatatttttt tcctctctgt gatggcctat
      361 gacagatacc ttgcaatcgc caagcccctg cactatgtga ccatgatgag gaaagaggtg
      421 tgggtggcct tggtggtggc ttcttgggtg agtggtggtt tgcattcaat catccaggta
      481 attctgatgc ttccattccc cttctgtggc cccaacacac tggatgcctt ctactgttat
      541 gtgctccagg tggtaaaact ggcctgcact gacacctttg ctttggagct tttcatgatc
      601 tctaacaacg gactggtgac cctgctctgg ttcctcctgc tcctgggctc ctacactgtc
      661 attctggtga tgctgagatc ccactctggg gaggggcgga acaaggccct ctccacgtgc
      721 acgtcccaca tgctggtggt gactcttcac ttcgtgcctt gtgtttacat ctactgccgg
      781 cccttcatga cgctgcccat ggacacaacc atatccatta ataacacggt cattaccccc
      841 atgctgaacc ccatcatcta ttccctgaga aatcaagaga tgaagtcagc catgcagagg
      901 ctgcagagga gacttgggcc ttccgagagc agaaaatggg ggtga
//
