LOCUS       NM_001004707            1551 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily D member 2
            (OR4D2), mRNA.
ACCESSION   NM_001004707 XM_064177
VERSION     NM_001004707.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1551)
  AUTHORS   Barnes,I.H.A., Ibarra-Soria,X., Fitzgerald,S., Gonzalez,J.M.,
            Davidson,C., Hardy,M.P., Manthravadi,D., Van Gerven,L.,
            Jorissen,M., Zeng,Z., Khan,M., Mombaerts,P., Harrow,J., Logan,D.W.
            and Frankish,A.
  TITLE     Expert curation of the human and mouse olfactory receptor gene
            repertoires identifies conserved coding regions split across two
            exons
  JOURNAL   BMC Genomics 21 (1), 196 (2020)
   PUBMED   32126975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1551)
  AUTHORS   Zody,M.C., Garber,M., Adams,D.J., Sharpe,T., Harrow,J.,
            Lupski,J.R., Nicholson,C., Searle,S.M., Wilming,L., Young,S.K.,
            Abouelleil,A., Allen,N.R., Bi,W., Bloom,T., Borowsky,M.L.,
            Bugalter,B.E., Butler,J., Chang,J.L., Chen,C.K., Cook,A., Corum,B.,
            Cuomo,C.A., de Jong,P.J., DeCaprio,D., Dewar,K., FitzGerald,M.,
            Gilbert,J., Gibson,R., Gnerre,S., Goldstein,S., Grafham,D.V.,
            Grocock,R., Hafez,N., Hagopian,D.S., Hart,E., Norman,C.H.,
            Humphray,S., Jaffe,D.B., Jones,M., Kamal,M., Khodiyar,V.K.,
            LaButti,K., Laird,G., Lehoczky,J., Liu,X., Lokyitsang,T.,
            Loveland,J., Lui,A., Macdonald,P., Major,J.E., Matthews,L.,
            Mauceli,E., McCarroll,S.A., Mihalev,A.H., Mudge,J., Nguyen,C.,
            Nicol,R., O'Leary,S.B., Osoegawa,K., Schwartz,D.C., Shaw-Smith,C.,
            Stankiewicz,P., Steward,C., Swarbreck,D., Venkataraman,V.,
            Whittaker,C.A., Yang,X., Zimmer,A.R., Bradley,A., Hubbard,T.,
            Birren,B.W., Rogers,J., Lander,E.S. and Nusbaum,C.
  TITLE     DNA sequence of human chromosome 17 and analysis of rearrangement
            in the human lineage
  JOURNAL   Nature 440 (7087), 1045-1049 (2006)
   PUBMED   16625196
REFERENCE   3  (bases 1 to 1551)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   4  (bases 1 to 1551)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC005962.1.
            
            On Aug 6, 2020 this sequence version replaced NM_001004707.3.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000545221.2/ ENSP00000441354.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                AC005962.1         88604-88675
            73-1551             AC005962.1         91260-92738
FEATURES             Location/Qualifiers
     source          1..1551
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q22"
     gene            1..1551
                     /gene="OR4D2"
                     /gene_synonym="BC2009; OR17-24"
                     /note="olfactory receptor family 4 subfamily D member 2"
                     /db_xref="GeneID:124538"
                     /db_xref="HGNC:HGNC:8294"
     exon            1..72
                     /gene="OR4D2"
                     /gene_synonym="BC2009; OR17-24"
                     /inference="alignment:Splign:2.1.0"
     exon            73..1551
                     /gene="OR4D2"
                     /gene_synonym="BC2009; OR17-24"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..1014
                     /gene="OR4D2"
                     /gene_synonym="BC2009; OR17-24"
                     /note="olfactory receptor OR17-24; G-protein coupled
                     membrane protein; B-lymphocyte membrane protein BC2009"
                     /codon_start=1
                     /product="olfactory receptor 4D2"
                     /protein_id="NP_001004707.1"
                     /db_xref="CCDS:CCDS32688.1"
                     /db_xref="GeneID:124538"
                     /db_xref="HGNC:HGNC:8294"
                     /translation="METGNLTWVSDFVFLGLSQTRELQRFLFLMFLFVYITTVMGNIL
                     IIITVTSDSQLHTPMYFLLRNLAVLDLCFSSVTAPKMLVDLLSEKKTISYQGCMGQIF
                     FFHFLGGAMVFFLSVMAFDRLIAISRPLRYVTVMNTQLWVGLVVATWVGGFVHSIVQL
                     ALMLPLPFCGPNILDNFYCDVPQVLRLACTDTSLLEFLKISNSGLLDVVWFFLLLMSY
                     LFILVMLRSHPGEARRKAASTCTTHIIVVSMIFVPSIYLYARPFTPFPMDKLVSIGHT
                     VMTPMLNPMIYTLRNQDMQAAVRRLGRHRLV"
ORIGIN      
        1 ggaaaacaac aaagcacaga attcgcccta tgagacttag agggaggatg ctcacagcaa
       61 aggacatcaa cggtgtatgg agaaaacacc atggaaacag ggaacctcac gtgggtatca
      121 gactttgtct tcctggggct ctcgcagact cgggagctcc agcgtttcct gtttctaatg
      181 ttcctgtttg tctacatcac cactgttatg ggaaacatcc ttatcatcat cacagtgacc
      241 tctgattccc agctccacac acccatgtac tttctgctcc gaaacctggc tgtcctagac
      301 ctctgtttct cttcagtcac tgctcccaaa atgctagtgg acctcctctc tgagaagaaa
      361 accatctctt accagggctg catgggtcag atcttcttct tccacttttt gggaggtgcc
      421 atggtcttct tcctctcagt gatggccttt gaccgcctca ttgccatctc ccggcccctc
      481 cgctatgtca ccgtcatgaa cactcagctc tgggtggggc tggtggtagc cacctgggtg
      541 ggaggctttg tccactctat tgtccagctg gctctgatgc tcccactgcc cttctgtggc
      601 cccaacattt tggataactt ctactgtgat gttccccaag tactgagact tgcctgcact
      661 gacacctcac tgctggagtt cctcaagatc tccaacagtg ggctgctgga tgtcgtctgg
      721 ttcttcctcc tcctgatgtc ctacttattc atcctggtga tgctgaggtc acatccaggg
      781 gaggcaagaa ggaaggcagc ttccacctgc accacccaca tcatcgtggt ttccatgatc
      841 ttcgttccaa gcatttacct ctatgcccgg cccttcactc cattccctat ggacaagctt
      901 gtgtccatcg gccacacagt catgaccccc atgctcaacc ccatgatcta taccctgagg
      961 aaccaggaca tgcaggcagc agtgagaaga ttagggagac accggctggt ttgagagtga
     1021 caatggtagg tttcttctct ttggctttgt tttccctttg tgaagtggag agggagctac
     1081 tacctttgct ctcttcatag tgtgttgagg ttcatcatag cagggaatga attttgaaac
     1141 taagcaactt cgtgttttag gaaaaaagaa agtatcctct ttggtggtta aggtttgtga
     1201 taaagagttt taacacactc gcaacaatga gaattgttca catggcccct gaaaaccaca
     1261 ccttcctttt caccttcttg gtggacagtt tcctgttgac agcatttccc ctgtgcgaac
     1321 atttctattt tccgtatttt gagctctctt cccaatattt ccttttggtg tgagtctggg
     1381 ttgttgggaa cagcacagaa tttggagtct taagctctaa attagaggcc ctgacccatc
     1441 attgaccaaa ctgatgactt cgagtaagcc acccagcttt tcttggcctc atgatttctc
     1501 cctcaccaat ttgcttaaat tagtatgtgc ccctaaaata ttctatgttt g
//
