LOCUS       NM_001348223             981 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily C member 5
            (OR4C5), mRNA.
ACCESSION   NM_001348223
VERSION     NM_001348223.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 981)
  AUTHORS   Olender,T., Waszak,S.M., Viavant,M., Khen,M., Ben-Asher,E.,
            Reyes,A., Nativ,N., Wysocki,C.J., Ge,D. and Lancet,D.
  TITLE     Personal receptor repertoires: olfaction as a model
  JOURNAL   BMC Genomics 13, 414 (2012)
   PUBMED   22908908
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 981)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC023080.6.
            
            On Nov 18, 2020 this sequence version replaced NM_001348223.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jan 2017].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments. This gene is a segregating
            pseudogene. This RefSeq represents the protein encoded by the
            reference genome allele, which is predicted to be functional
            according to the Classifier for Olfactory Receptor Pseudogenes.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000319813.3/ ENSP00000321338.3
            polymorphic pseudogene :: PMID: 22908908
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-981               AC023080.6         91486-92466
FEATURES             Location/Qualifiers
     source          1..981
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p11.2"
     gene            1..981
                     /gene="OR4C5"
                     /gene_synonym="OR4C5P; OR4C5Q"
                     /note="olfactory receptor family 4 subfamily C member 5"
                     /db_xref="GeneID:79346"
                     /db_xref="HGNC:HGNC:14702"
     CDS             1..981
                     /gene="OR4C5"
                     /gene_synonym="OR4C5P; OR4C5Q"
                     /note="olfactory receptor, family 4, subfamily C, member 5
                     pseudogene; olfactory receptor OR11-99; seven
                     transmembrane helix receptor"
                     /codon_start=1
                     /product="olfactory receptor 4C5"
                     /protein_id="NP_001335152.1"
                     /db_xref="CCDS:CCDS86201.1"
                     /db_xref="GeneID:79346"
                     /db_xref="HGNC:HGNC:14702"
                     /translation="MYVSNCNPCAIHRKINYPNTKLDFEQVNNITEFILLGLTQNAEA
                     QKLLFAVFTLIYFLTMVDNLIIVVTITTSPALDSPVYFFLSFFSFIDGCSSSTMAPKM
                     IFDLLTEKKTISFSGCMTQLFVEHFFGGVEIILLVVMAYDCYVAICKPLYYLITMNRQ
                     VCGLLVAMAWVGGFLHALIQMLLIVWLPFCGPNVIDHFICDLFPLLKLSCTDTHVFGL
                     FVAANSGLMCMLIFSILITSYVLILCSQRKALSTCAFHITVVVLFFVPCILVYLRPMI
                     TFPIDKAVSVFYTVVTPMLNPLIYTLRNTEVKNAMKQLWSQIIWGNNLCD"
     exon            1..981
                     /gene="OR4C5"
                     /gene_synonym="OR4C5P; OR4C5Q"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtatgtgt caaattgcaa tccttgtgct attcacagaa aaatcaatta tccaaatacc
       61 aaactggatt tcgagcaagt gaacaacata acggaattca tcttgcttgg cctgacacag
      121 aacgcagagg cacagaaact cttgtttgct gtgtttacac tcatctactt tctcaccatg
      181 gtagacaacc taatcattgt ggtgacaatc accaccagcc cagccctgga ctcccccgtg
      241 tatttttttc tgtctttctt ttccttcata gatggctgct cctcttctac catggccccc
      301 aaaatgatat ttgacttact cactgaaaag aaaactattt ccttcagtgg gtgcatgacc
      361 cagctctttg tagaacattt ctttggggga gttgagatca ttctgctcgt ggtgatggcc
      421 tatgactgct atgtggccat ctgcaagccc ctgtactacc tgatcacaat gaacaggcag
      481 gtatgtggcc tcctggtggc catggcatgg gtcgggggat ttcttcacgc tctgattcaa
      541 atgcttttaa tagtctggct gcccttctgt ggccccaatg tcattgacca tttcatctgt
      601 gaccttttcc ctctgctaaa actctcctgc actgacactc acgtctttgg actctttgtt
      661 gccgccaaca gtgggctgat gtgtatgctc attttttcta ttcttattac ctcttacgtc
      721 ctaatcctct gctcacagcg gaaggctctc tctacctgcg ccttccatat cactgtagtc
      781 gtcctattct ttgttccctg tatattggtg taccttcgac ccatgatcac cttccctatt
      841 gataaagctg tgtctgtgtt ttatactgtg gtaacaccca tgttaaaccc tttaatctac
      901 accctcagaa acacagaggt gaaaaatgcc atgaagcagc tctggagcca aataatctgg
      961 ggtaacaatt tgtgtgatta g
//
