LOCUS       NM_001005270            1063 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 4 subfamily C member 12
            (OR4C12), mRNA.
ACCESSION   NM_001005270 XM_210169
VERSION     NM_001005270.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Miller,S., Rogers,H.A., Lyon,P., Rand,V., Adamowicz-Brice,M.,
            Clifford,S.C., Hayden,J.T., Dyer,S., Pfister,S., Korshunov,A.,
            Brundler,M.A., Lowe,J., Coyle,B. and Grundy,R.G.
  TITLE     Genome-wide molecular characterization of central nervous system
            primitive neuroectodermal tumor and pineoblastoma
  JOURNAL   Neuro Oncol 13 (8), 866-879 (2011)
   PUBMED   21798848
REFERENCE   2  (bases 1 to 1063)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   3  (bases 1 to 1063)
  AUTHORS   Fuchs,T., Malecova,B., Linhart,C., Sharan,R., Khen,M., Herwig,R.,
            Shmulevich,D., Elkon,R., Steinfath,M., O'Brien,J.K., Radelof,U.,
            Lehrach,H., Lancet,D. and Shamir,R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC110057.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Apr 15, 2014 this sequence version replaced NM_001005270.3.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC136850.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000335238.4/ ENSP00000334418.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1063              AC110057.3         86472-87534
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p11.12"
     gene            1..1063
                     /gene="OR4C12"
                     /gene_synonym="OR11-259"
                     /note="olfactory receptor family 4 subfamily C member 12"
                     /db_xref="GeneID:283093"
                     /db_xref="HGNC:HGNC:15168"
     exon            1..1063
                     /gene="OR4C12"
                     /gene_synonym="OR11-259"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..964
                     /gene="OR4C12"
                     /gene_synonym="OR11-259"
                     /note="olfactory receptor OR11-259; seven transmembrane
                     helix receptor"
                     /codon_start=1
                     /product="olfactory receptor 4C12"
                     /protein_id="NP_001005270.3"
                     /db_xref="CCDS:CCDS31496.1"
                     /db_xref="GeneID:283093"
                     /db_xref="HGNC:HGNC:15168"
                     /translation="MEKKKNVTEFILIGLTQNPIMEKVTFVVFLVLYMITLSGNLLIV
                     VTITTSQALSSPMYFFLTHLSLIDTVYSSSSAPKLIVDSFQEKKIISFNGCMAQAYAE
                     HIFGATEIILLTVMACDCYVAICKPLNYTTIMSHSLCILLVAVAWVGGFLHATIQILF
                     TVWLPFCGPNVIGHFMCDLYPLLKLVCIDTHTLGLFVAVNSGFICLLNFLILVVSYVI
                     ILRSLKNNSLEGRCKALSTCISHIIVVVLFFVPCIFVYLRSVTTLPIDKAVAVFYTMV
                     VPMLNPVVYTLRNAEVKSAIRKLWRKKVTSDND"
ORIGIN      
        1 ccttcctgga ggttttatca cccacactac atagatggag aagaaaaaga atgtgactga
       61 attcatttta ataggtctta cacagaaccc cataatggag aaagtcacgt ttgtagtatt
      121 tttggttctt tacatgataa cactttcagg caacctgctc attgtggtta ccattaccac
      181 cagccaggct ctgagctccc ccatgtactt cttcctgacc cacctttctt tgatagacac
      241 agtttattct tcttcttcag ctcctaagtt gattgtggat tcctttcaag agaagaaaat
      301 catctccttt aatgggtgta tggctcaagc ctatgcagaa cacatttttg gtgctactga
      361 gatcatcctg ctgacagtga tggcctgtga ctgctatgtg gccatctgca aacctctgaa
      421 ctacacaacc attatgagcc acagcctgtg cattctcctg gtggcagtgg cctgggtggg
      481 aggatttctt catgcaacta ttcagattct ctttacagta tggctgccct tctgtggccc
      541 caatgtcata ggccacttca tgtgtgactt gtacccattg ttaaaacttg tttgcataga
      601 cactcatacc cttggtctct ttgttgctgt gaacagtggg tttatctgct tattaaactt
      661 ccttatcttg gtggtatcct atgtgatcat cttgagatct ttaaagaaca atagcttgga
      721 ggggaggtgt aaagccctct ccacctgtat ttctcacatc atagtagttg tcttattctt
      781 tgtgccctgt atatttgtgt atctgcgctc agtgaccact ctgcccattg ataaagctgt
      841 tgctgtattt tatactatgg tggtcccaat gttaaatccc gtggtctaca cactcagaaa
      901 tgctgaggta aaaagtgcaa taaggaagct ttggagaaaa aaagtgactt cagataatga
      961 ttaaataaga ccattgagca ctcaacatag aggtaatagg tatttaagct tcttgatttg
     1021 tagatgaata tgtcaactct aacaaggggc tggctaatgc ttg
//
